Buchanan laboratory: Oncogenomics (colorectal cancer)
Research Program Leader : Dr Daniel BuchananThe Oncogenomics Group research includes the identification and investigation of clinically and biologically relevant subtypes of colorectal cancer (CRC), including both familial and non-familial CRC, that can be identified through genetic, epigenetic, somatic and histopathological characterisation of CRC tumours and their pre-malignant lesions (polyps).
Hollande laboratory: Molecular mechanisms of tumour progression
Research Program Leader : Associate Professor Fred Hollande
The main focus of our work is to characterise signalling pathways that specify the role of tumour-initiating cells in cancer progression towards the metastatic stage, and to determine the respective contributions of intrinsic programs and of extrinsic/micro-environmental cues in the control of these signalling events.
Southey laboratory: Genetic epidemiology laboratory
Research Program Leader : Professor Melissa Southey
Our research programs are focused on characterising the genetic and epigenetic factors responsible for cancer predisposition and progression, including familial aggregation of cancers.