Boussioutas Laboratory: Gastrointestinal Cancer
My research team investigates translational aspects of gastrointestinal oncology. My research disciplines span population health and epidemiology of gastric and colorectal cancer, integrative genomic analysis of gastric and oesophageal cancer, cell biology of invasion and metastasis with respect to the tumour microenvironment, early detection and biomarkers of gastric cancer and genetic aspects of gastrointestinal malignancies.
My team is currently engaged in a number of research areas mainly in understanding cellular and molecular aspects of upper gastrointestinal cancers like gastric cancer and oesophageal adenocarcinoma. Particular areas of research include: (a) Understanding premalignant stages of disease (intestinal metaplasia) and how they progress to cancer to allow prevention strategies; (b) Tumour microenvironment and how this influences outcomes of disease in gastric cancer; (c) Biomarkers and precision medicine to be able to discover biomarkers for screening and early detection of cancer.
I also have an interest in screening and prevention of colorectal cancer particularly in high risk populations like those patients with hereditary predisposition to colorectal cancer.
- Natasha Di Costanzo, Research Assistant
- Dr Rita Busuttil, Postdoctoral Fellow
- Minyu Wang, PhD Student
- Yu-Kuan Huang, PhD student
- Athanasios Koulis, PhD student
- Elise Cannan, Scholarly Selective Student
- Dr Adam Bass, The Cancer Genome Atlas, NCI/NIH, USA
- Prof Matthias Ernst, Olivia Newton John Cancer Research Institute, Melbourne, Australia
- Prof Patrick Tan, National University of Singapore, Singapore
- Prof Rebecca Fitzgerald, Cambridge University, Cambridge, UK
- Prof Mark Jenkins, University of Melbourne, Melbourne, Australia
- Prof Jon Emery, University of Melbourne, Melbourne Australia
- 2015-2016NHMRC Project Grant (APP1087683) Molecular epidemiology of gastric cancers
- 2013-2017Centre for Research Excellence (APP1042021) Centre for Research Excellence for reducing the burden of colorectal câncer by optimising screening: evidence to clinical practice
- 2013-2017NHMRC Project Grant PP1046425: A randomised phase III Trial of preoperative chemoradiotherapy VS preoperative chemotherapy for resectable gastric cancer
- 2013-2015NHMRC Project Grant (APP1065303) Colorectal Cancer screening: uptake and outcomes
- 2012-2015NHMRC Project Grant APP1030980: Establishment of a biomarker to test molecular risk of Gastric Cancer
This research project is available to PhD students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
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