Single Event Multilevel Surgery in Bilateral Spastic Cerebral Palsy: A Multi-centre, Long-term, Follow-up Study

Project Details

Single Event Multilevel Surgery (SEMLS) is considered the standard of care for orthopaedic surgical intervention in children with bilateral spastic cerebral palsy (BSCP). The efficacy of SEMLS is supported by one randomized clinical trial and many cohort studies. However, the majority of studies have limited numbers and short term follow up. The purpose of this study was to investigate the efficacy and safety of SEMLS and to determine if improvements are maintained in the long term.

This study is a large, multi-centre, retrospective, cohort study of children and youth with BSCP with short and long term follow up after SEMLS. Data was collected prospectively, using standardized gait laboratory protocols and analyzed retrospectively, using a summary statistic of gait, the Gait Profile Score (GPS).

Collaborators

  • NH&MRC CP-CRE, Chief Investigators: Professor Dinah Reddihough, Professor H.Kerr Graham, Professor Christine Imms, Professor Nadia Badawi, Associate Professor Michael Coory, Professor Eve Blair, Professor Rob Carter.
  • Canadian Institutes of Health Research: Professor Unni Narayanan, Dr Darcy Fehlings, Professor H. Kerr Graham, Dr R Hamdy, Dr Kishore Mulpuri.

Funding

The Hugh Williamson Foundation has provided funding for the Melbourne component of this study.

Research Opportunities

This research project is available to PhD, Masters, Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Outcomes

The study has been completed and a paper is under review.

Research Group

Hugh Williamson Gait Laboratory/Orthopaedic Department



Faculty Research Themes

Child Health

School Research Themes

Child Health in Medicine, Musculoskeletal



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Paediatrics