Infectious Diseases Group

Research Overview

Under the campus partnership, our research is embedded in MCRI.  Full research profile may be found at https://www.mcri.edu.au/research/themes/infection-and-immunity/infectious-diseases-microbiology or https://www.mcri.edu.au/users/professor-nigel-curtis

The research of the Infectious Diseases Group focuses on improving the diagnosis, treatment and prevention of infectious diseases in children. It comprises both clinical and laboratory-based research studies. The clinical research aspect includes randomised controlled trials, observational studies and systematic reviews of best practice. Our laboratory research encompasses basic and applied medical microbiology, as well as immunological studies to explore the mechanisms by which pathogens cause disease and their interaction with the host immune response.

We have a particular interest in infections that are important to child health worldwide such as tuberculosis and other respiratory infections, diarrhoeal illnesses and neonatal sepsis. A major focus of our research involves improving the diagnosis of childhood tuberculosis by identifying and validating novel cytokine biomarkers. Another key focus of our current work is the investigation of the heterologous effects of BCG vaccination. Our team is investigating the hypothesis that the immunomodulatory effects of BCG influence the development of infant immunity to enhance protection against infections and reduce susceptibility to allergic disease. In a large randomised controlled trial, the Melbourne Infant Study: BCG for Allergy and Infection Reduction (MIS BAIR), we are closely following over 1200 infants over the first five years of life with embedded clinical and immunological studies.

Collaborators

International Collaborations:

  • Radboud University Nijmegen Medical Centre, The Netherlands
  • University of British Columbia, Canada
  • Peruvian University Cayetano Heredia, Lima, Peru
  • University of Oxford

Funding

  • National Health and Medical Research Council
  • John Burge Trust

Research Publications

1. Corticosteroids and infliximab impair the performance of interferon-γ release assays used for diagnosis of latent tuberculosis.

Edwards A, Gao Y, Allan RN, Ball D, de Graaf H, Coelho T, Clifford V, Curtis N, Williams A, Faust SN, Mansour S, Marshall B, Elkington P, Tebruegge M.

Thorax. 2017 Feb 3. pii: thoraxjnl-2016-209397. doi: 10.1136/thoraxjnl-2016-209397. [Epub ahead of print]

PMID: 28159773

Similar articles Select item 28137805

2. Antimicrobial Effects of Antipyretics.

Zimmermann P, Curtis N.

Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02268-16. doi: 10.1128/AAC.02268-16. [Epub ahead of print]

PMID: 28137805

Similar articles Select item 28114153

3. Mycobacterium gordonae Skin Infection in an Immunocompetent Child.

Freyne B, Curtis N.

Pediatr Infect Dis J. 2017 Jan 19. doi: 10.1097/INF.0000000000001549. [Epub ahead of print]

PMID: 28114153

Similar articles Select item 28094311

4. Evidence of Microvascular Changes in the Retina following Kawasaki Disease.

Chen KY, Burgner DP, Wong TY, Saw SM, Quek SC, Pang AY, Leo SW, Wong IB, Zannino D, Curtis N, Cheung M, Cheung CY, Lim TC.

Sci Rep. 2017 Jan 17;7:40513. doi: 10.1038/srep40513.

PMID: 28094311 Free PMC Article

Similar articles Select item 28033242

5. Brachial Plexus Palsy in Young Infants Harboring Osteomyelitis of the Humerus - Case Report and Review of the Literature.

Zimmermann P, Curtis N.

Pediatr Infect Dis J. 2016 Dec 28. doi: 10.1097/INF.0000000000001520. [Epub ahead of print]

PMID: 28033242

Similar articles Select item 27872104

6. Potential role for BCG in treatment of autoimmune diseases.

Curtis N.

BMJ. 2016 Nov 21;355:i6091. doi: 10.1136/bmj.i6091. No abstract available.

PMID: 27872104

Similar articles Select item 27506394

7. A personalised approach is needed for the management of non-tuberculous mycobacterial cervicofacial lymphadenitis.

Zimmermann P, Tebruegge M, Curtis N, Ritz N.

J Infect. 2016 Oct;73(4):391-2. doi: 10.1016/j.jinf.2016.07.017. No abstract available.

PMID: 27506394

Similar articles Select item 27416010

8. Interferon-gamma Release Assays Should Not Replace Tuberculin Skin Tests in Screening Programs for Children.

Tebruegge M, Clifford V, Curtis N.

Pediatr Infect Dis J. 2016 Aug;35(8):929. doi: 10.1097/INF.0000000000001195. No abstract available.

PMID: 27416010

Similar articles Select item 27396518

9. Comparable CD4 and CD8 T cell responses and cytokine release after at-birth and delayed BCG immunisation in infants born in Australia.

Ritz N, Casalaz D, Donath S, Tebruegge M, Dutta B, Connell TG, Robins-Browne R, Britton WJ, Hanekom WA, Curtis N.

Vaccine. 2016 Jul 29;34(35):4132-9. doi: 10.1016/j.vaccine.2016.06.077.

PMID: 27396518

Similar articles Select item 27339109

10. Preface.Curtis N, Pollard AJ, Finn A, Ramilo O, Dobson S, Warris A, van Rossum A.

J Infect. 2016 Jul 5;72 Suppl:1. doi: 10.1016/j.jinf.2016.06.003. No abstract available.

PMID: 27339109

Similar articles Select item 27321363

11. Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines.

McMullan BJ, Andresen D, Blyth CC, Avent ML, Bowen AC, Britton PN, Clark JE, Cooper CM, Curtis N, Goeman E, Hazelton B, Haeusler GM, Khatami A, Newcombe JP, Osowicki J, Palasanthiran P, Starr M, Lai T, Nourse C, Francis JR, Isaacs D, Bryant PA; ANZPID-ASAP group..

Lancet Infect Dis. 2016 Aug;16(8):e139-52. doi: 10.1016/S1473-3099(16)30024-X. Review.

PMID: 27321363

Similar articles Select item 27312004

12. QUESTION 1: Teething issues: can doxycycline be safely used in young children?

Boast A, Curtis N, Gwee A.

Arch Dis Child. 2016 Aug;101(8):772-4. doi: 10.1136/archdischild-2016-310964. No abstract available.

PMID: 27312004

Similar articles Select item 27263075

13.Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome - A challenging diagnosis not to be missed.

Zimmermann P, Curtis N.

J Infect. 2016 Jul 5;72 Suppl:S106-14. doi: 10.1016/j.jinf.2016.04.030.

PMID: 27263075

Similar articles Select item 27157064

14.Harnessing the beneficial heterologous effects of vaccination.

Goodridge HS, Ahmed SS, Curtis N, Kollmann TR, Levy O, Netea MG, Pollard AJ, van Crevel R, Wilson CB.

Nat Rev Immunol. 2016 Jun;16(6):392-400. doi: 10.1038/nri.2016.43. Review.

PMID: 27157064 Free PMC Article

Similar articles Select item 27117838

15.Toxic shock syndrome in Australian children.

Chen KY, Cheung M, Burgner DP, Curtis N.

Arch Dis Child. 2016 Aug;101(8):736-40. doi: 10.1136/archdischild-2015-310121.

PMID: 27117838

Similar articles Select item 27016867

16.Interrupted BCG vaccination is a major threat to global child health.

Marais BJ, Seddon JA, Detjen AK, van der Werf MJ, Grzemska M, Hesseling AC, Curtis N, Graham SM; WHO Child TB Subgroup..

Lancet Respir Med. 2016 Apr;4(4):251-3. doi: 10.1016/S2213-2600(16)00099-0. No abstract available.

PMID: 27016867

Similar articles Select item 27009030

17.Voriconazole dosing and therapeutic drug monitoring in children: experience from a paediatric tertiary care centre.

Boast A, Curtis N, Cranswick N, Gwee A.

J Antimicrob Chemother. 2016 Jul;71(7):2031-6. doi: 10.1093/jac/dkw056.

PMID: 27009030

Similar articles Select item 26880292

18.Kawasaki disease and cardiovascular risk: a comprehensive review of subclinical vascular changes in the longer term.

Chen KY, Curtis N, Dahdah N, Kowalski R, Cheung M, Burgner DP.

Acta Paediatr. 2016 Jul;105(7):752-61. doi: 10.1111/apa.13367. Review.

PMID: 26880292

Similar articles Select item 26812154

19.Nontuberculous Mycobacterial Disease in Children - Epidemiology, Diagnosis & Management at a Tertiary Center.

Tebruegge M, Pantazidou A, MacGregor D, Gonis G, Leslie D, Sedda L, Ritz N, Connell T, Curtis N.

PLoS One. 2016 Jan 26;11(1):e0147513. doi: 10.1371/journal.pone.0147513.

PMID: 26812154 Free PMC Article

Similar articles Select item 26792903

20.QUESTION 1: Are household contacts of patients with invasive group A streptococcal disease at higher risk of secondary infection?

Carr JP, Curtis N, Smeesters PR, Steer A.

Arch Dis Child. 2016 Feb;101(2):198-201. doi: 10.1136/archdischild-2015-309788. Review. No abstract available.

PMID: 26792903

Similar articles Select item 26674499

21.VITALITY trial: protocol for a randomised controlled trial to establish the role of postnatal vitamin D supplementation in infant immune health.

Allen KJ, Panjari M, Koplin JJ, Ponsonby AL, Vuillermin P, Gurrin LC, Greaves R, Carvalho N, Dalziel K, Tang ML, Lee KJ, Wake M, Curtis N, Dharmage SC.

BMJ Open. 2015 Dec 16;5(12):e009377. doi: 10.1136/bmjopen-2015-009377.

PMID: 26674499 Free PMC Article

Similar articles Select item 26515270

22.Interferon gamma release assays for monitoring the response to treatment for tuberculosis: A systematic review.

Clifford V, He Y, Zufferey C, Connell T, Curtis N.

Tuberculosis (Edinb). 2015 Dec;95(6):639-50. doi: 10.1016/j.tube.2015.07.002. Review.

PMID: 26515270

Similar articles Select item 26408788

23.Question 1: Co-trimoxazole dosing dilemma: what is the right dose?

Boast A, Osowicki J, Cole T, Curtis N, Gwee A.

Arch Dis Child. 2015 Nov;100(11):1089-93. doi: 10.1136/archdischild-2015-309100. Review. No abstract available.

PMID: 26408788

Similar articles

Select item 26350382

24.Sharps injuries in the community: lower risk than in healthcare settings.

Osowicki J, Curtis N.

BMJ. 2015 Sep 8;351:h4766. doi: 10.1136/bmj.h4766. No abstract available.

PMID: 26350382

Similar articles Select item 26322512

25.Monitoring Central Venous Catheter Resistance to Predict Imminent Occlusion: A Prospective Pilot Study.

Wolf J, Tang L, Rubnitz JE, Brennan RC, Shook DR, Stokes DC, Monagle P, Curtis N, Worth LJ, Allison K, Sun Y, Flynn PM.

PLoS One. 2015 Aug 31;10(8):e0135904. doi: 10.1371/journal.pone.0135904.

PMID: 26322512 Free PMC Article

Similar articles Select item 26303111

26.Effective CSF concentrations achieved with continuous-infusion flucloxacillin in a child.

Boast A, Carr J, Curtis N, Daley AJ, Gwee A.

Eur J Clin Pharmacol. 2015 Dec;71(12):1535-7. doi: 10.1007/s00228-015-1928-6. No abstract available.

PMID: 26303111

Similar articles Select item 26271898

27.Serum IP-10 in the diagnosis of latent and active tuberculosis.

Clifford V, Tebruegge M, Zufferey C, Germano S, Denholm J, Street A, McBryde E, Eisen D, Curtis N.

J Infect. 2015 Dec;71(6):696-8. doi: 10.1016/j.jinf.2015.08.001. No abstract available.

PMID: 26271898

Similar articles Select item 26270790

28.Streptococcal Serology: Secrets for the Specialist.

Steer AC, Smeesters PR, Curtis N.

Pediatr Infect Dis J. 2015 Nov;34(11):1250-2. doi: 10.1097/INF.0000000000000881. Review. No abstract available.

PMID: 26270790

Similar articles Select item 26107342

29.Diagnostic Tests for Childhood Tuberculosis: Past Imperfect, Present Tense and Future Perfect?

Tebruegge M, Ritz N, Curtis N, Shingadia D.

Pediatr Infect Dis J. 2015 Sep;34(9):1014-9. doi: 10.1097/INF.0000000000000796. Review. No abstract available.

PMID: 26107342

Similar articles Select item 26068678

30.BCG for the prevention of food allergy - exploring a new use for an old vaccine.

Kiraly N, Allen KJ, Curtis N.

Med J Aust. 2015 Jun 15;202(11):565-6. No abstract available.

PMID: 26068678

Similar articles Select item 26030187

31.Mycobacteria-Specific Cytokine Responses Detect Tuberculosis Infection and Distinguish Latent from Active Tuberculosis.

Tebruegge M, Dutta B, Donath S, Ritz N, Forbes B, Camacho-Badilla K, Clifford V, Zufferey C, Robins-Browne R, Hanekom W, Graham SM, Connell T, Curtis N.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):485-99. doi: 10.1164/rccm.201501-0059OC.

PMID: 26030187

Similar articles Select item 25973938

32.Posaconazole: promising but problematic in practice in pediatric patients.

Gwee A, Cranswick N, Curtis N.

Pediatr Infect Dis J. 2015 Jun;34(6):604-6. doi: 10.1097/INF.0000000000000635. Review.

PMID: 25973938

Similar articles Select item 25961896

33.Australia-wide Point Prevalence Survey of Antimicrobial Prescribing in Neonatal Units: How Much and How Good?

Osowicki J, Gwee A, Noronha J, Britton PN, Isaacs D, Lai TB, Nourse C, Avent M, Moriarty P, Francis JR, Blyth CC, Cooper CM, Bryant PA; ANZPID-ASAP group (Australian and New Zealand Paediatric Infectious Diseases-Australasian Stewardship of Antimicrobials in Paediatrics)..

Pediatr Infect Dis J. 2015 Aug;34(8):e185-90. doi: 10.1097/INF.0000000000000719.

PMID: 25961896

Similar articles Select item 25921753

34.Limitations of current tuberculosis screening tests in immunosuppressed patients.

Clifford V, Tebruegge M, Curtis N.

BMJ. 2015 Apr 28;350:h2226. doi: 10.1136/bmj.h2226. No abstract available.

PMID: 25921753

Similar articles Select item 25837441

35.The impact of anti-tuberculous antibiotics and corticosteroids on cytokine production in QuantiFERON-TB Gold In Tube assays.

Clifford V, Zufferey C, Germano S, Ryan N, Leslie D, Street A, Denholm J, Tebruegge M, Curtis N.

Tuberculosis (Edinb). 2015 May;95(3):343-9. doi: 10.1016/j.tube.2015.02.039.

PMID: 25837441

Similar articles Select item 25797612

36.Cytokines for monitoring anti-tuberculous therapy: A systematic review.

Clifford V, Zufferey C, Street A, Denholm J, Tebruegge M, Curtis N.

Tuberculosis (Edinb). 2015 May;95(3):217-28. doi: 10.1016/j.tube.2015.01.003. Review.

PMID: 25797612

Similar articles Select item 25770252

37.BCG-associated heterologous immunity, a historical perspective: intervention studies in animal models of infectious diseases.

Freyne B, Marchant A, Curtis N.

Trans R Soc Trop Med Hyg. 2015 Apr;109(4):287. doi: 10.1093/trstmh/trv021. No abstract available.

PMID: 25770252

Similar articles Select item 25760572

38.A cautionary tale about treatment of neonatal enteroviral disease.

Bryant PA, Curtis N.

Pediatr Infect Dis J. 2015 Apr;34(4):460. doi: 10.1097/INF.0000000000000588. No abstract available.

PMID: 25760572

Similar articles

Select item 25727993

39.The management of non-tuberculous cervicofacial lymphadenitis in children: A systematic review and meta-analysis.

Zimmermann P, Tebruegge M, Curtis N, Ritz N.

J Infect. 2015 Jul;71(1):9-18. doi: 10.1016/j.jinf.2015.02.010. Review.

PMID: 25727993

Similar articles Select item 25669475

40.Antimicrobial stewardship resources and activities for children in tertiary hospitals in Australasia: a comprehensive survey.

Bryant PA; Australasian Stewardship of Antimicrobials in Paediatrics group..

Med J Aust. 2015 Feb 16;202(3):134-8.

PMID: 25669475

Similar articles Select item 25573109

41.BCG-associated heterologous immunity, a historical perspective: intervention studies in animal models of infectious diseases.

Freyne B, Marchant A, Curtis N.

Trans R Soc Trop Med Hyg. 2015 Jan;109(1):52-61. doi: 10.1093/trstmh/tru197. Review. Erratum in: Trans R Soc Trop Med Hyg. 2015 Apr;109(4):287.

PMID: 25573109

Similar articles Select item 25573108

42.BCG-associated heterologous immunity, a historical perspective: experimental models and immunological mechanisms.

Freyne B, Marchant A, Curtis N.

Trans R Soc Trop Med Hyg. 2015 Jan;109(1):46-51. doi: 10.1093/trstmh/tru196. Review.

PMID: 25573108

Similar articles Select item 25560708

43.ASO titer or not? When to use streptococcal serology: a guide for clinicians.

Parks T, Smeesters PR, Curtis N, Steer AC.

Eur J Clin Microbiol Infect Dis. 2015 May;34(5):845-9. doi: 10.1007/s10096-014-2303-8. Review.

PMID: 25560708

Similar articles Select item 25395586

44.Toxic shock syndrome: under-recognised and under-treated?

Curtis N.

Arch Dis Child. 2014 Dec;99(12):1062-4. doi: 10.1136/archdischild-2014-306601. No abstract available.

PMID: 25395586

Similar articles Select item 25389253

45.Hospital-wide rollout of antimicrobial stewardship: a stepped-wedge randomized trial.

Freyne B, Carr J, Osowicki J, Steer A, Curtis N, Bryant PA.

Clin Infect Dis. 2015 Feb 15;60(4):666. doi: 10.1093/cid/ciu899. No abstract available.

PMID: 25389253

Similar articles Select item 25361191

46.Minimizing nephrotoxicity using continuous infusion of deoxycholate amphotericin B.

Gwee A, Cranswick N, Connell TG, Curtis N.

Pediatr Infect Dis J. 2014 Oct;33(10):1098. doi: 10.1097/INF.0000000000000380. No abstract available.

PMID: 25361191

Similar articles Select item 25344543

47.Reply to Banderet-Uglioni et al.

Carapetis JR, Jacoby P, Carville K, Ang SJ, Curtis N, Andrews R.

Clin Infect Dis. 2015 Jan 15;60(2):323-4. doi: 10.1093/cid/ciu829. No abstract available.

PMID: 25344543

Similar articles Select item 25301755

48.Hot topics in infection and immunity in children.

Curtis N, Pollard AJ, Finn A.

J Infect. 2014 Nov;69 Suppl 1:S1. doi: 10.1016/j.jinf.2014.09.009. No abstract available.

PMID: 25301755

Similar articles Select item 25207918

49.Novel concepts in the epidemiology, diagnosis and prevention of childhood tuberculosis.

Ritz N, Curtis N.

Swiss Med Wkly. 2014 Sep 10;144:w14000. doi: 10.4414/smw.2014.14000. Review.

PMID: 25207918 Free Article

Similar articles Select item 25165072

50.Question 2: A pointed question: is a child at risk following a community-acquired needlestick injury?

Osowicki J, Curtis N.

Arch Dis Child. 2014 Dec;99(12):1172-5. doi: 10.1136/archdischild-2014-306929. Review. No abstract available.

PMID: 25165072

Similar articles Select item 25138103

51.Orange alert.

Osowicki J, Curtis N.

Arch Dis Child. 2014 Oct;99(10):964. doi: 10.1136/archdischild-2014-307052. No abstract available.

PMID: 25138103

Similar articles Select item 24953486

52.Wash your hands after playing with that dragon!

Wolf J, Curtis N.

J Paediatr Child Health. 2014 Dec;50(12):1023-4. doi: 10.1111/jpc.12633. No abstract available.

PMID: 24953486

Similar articles Select item 24897091

53.Causes of fever in outpatient Tanzanian children.

Osowicki J, Curtis N.

N Engl J Med. 2014 Jun 5;370(23):2242-3. doi: 10.1056/NEJMc1403839#SA2. No abstract available.

PMID: 24897091

Similar articles

Select item 24891428

54.Pristinamycin: old drug, new tricks?

Cooper EC, Curtis N, Cranswick N, Gwee A.

J Antimicrob Chemother. 2014 Sep;69(9):2319-25. doi: 10.1093/jac/dku167. Review.

PMID: 24891428

Similar articles Select item 24799598

55.A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development.

Sanderson-Smith M, De Oliveira DM, Guglielmini J, McMillan DJ, Vu T, Holien JK, Henningham A, Steer AC, Bessen DE, Dale JB, Curtis N, Beall BW, Walker MJ, Parker MW, Carapetis JR, Van Melderen L, Sriprakash KS, Smeesters PR; M Protein Study Group..

J Infect Dis. 2014 Oct 15;210(8):1325-38. doi: 10.1093/infdis/jiu260.

PMID: 24799598

Similar articles Select item 24785239

56.Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections.

Carapetis JR, Jacoby P, Carville K, Ang SJ, Curtis N, Andrews R.

Clin Infect Dis. 2014 Aug 1;59(3):358-65. doi: 10.1093/cid/ciu304.

PMID: 24785239

Similar articles Select item 24704706

57. Question 2: which infants with congenital cytomegalovirus infection benefit from antiviral therapy?

Gwee A, Curtis N, Garland SM, Connell TG, Daley AJ.

Arch Dis Child. 2014 Jun;99(6):597-601. doi: 10.1136/archdischild-2014-306082. Review. No abstract available.

PMID: 24704706

Similar articles Select item 24528424

58.Infants born in Australia to mothers from countries with a high prevalence of tuberculosis: to BCG or not to BCG? In reply.

Gwee A, Rodrigo R, Casalaz D, Ritz N, Curtis N.

Med J Aust. 2014 Feb 17;200(3):149-50. No abstract available.

PMID: 24528424

Similar articles Select item 24478089

59.Susceptibility to acute rheumatic fever based on differential expression of genes involved in cytotoxicity, chemotaxis, and apoptosis.

Bryant PA, Smyth GK, Gooding T, Oshlack A, Harrington Z, Currie B, Carapetis JR, Robins-Browne R, Curtis N.

Infect Immun. 2014 Feb;82(2):753-61. doi: 10.1128/IAI.01152-13.

PMID: 24478089 Free PMC Article

Similar articles Select item 24420614

60.Does neonatal BCG vaccination prevent allergic disease in later life?

Freyne B, Curtis N.

Arch Dis Child. 2014 Feb;99(2):182-4. doi: 10.1136/archdischild-2013-305655. Review. No abstract available.

PMID: 24420614

Similar articles Select item 24403544

61.Long-term persistence of immunity and B-cell memory following Haemophilus influenzae type B conjugate vaccination in early childhood and response to booster.

Perrett KP, John TM, Jin C, Kibwana E, Yu LM, Curtis N, Pollard AJ.

Clin Infect Dis. 2014 Apr;58(7):949-59. doi: 10.1093/cid/ciu001.

PMID: 24403544

Similar articles Select item 24378952

62.Neonatal vancomycin continuous infusion: still a confusion?

Gwee A, Cranswick N, Metz D, Coghlan B, Daley AJ, Bryant PA, Curtis N.

Pediatr Infect Dis J. 2014 Jun;33(6):600-5. doi: 10.1097/INF.0000000000000243. Review.

PMID: 24378952

Similar articles Select item 24378949

63.Formal infectious diseases consultations at a tertiary pediatric hospital: a 14-year review.

Gwee A, Carapetis JR, Buttery J, Starr M, Connell TG, Steer A, Bryant PA, Curtis N.

Pediatr Infect Dis J. 2014 Apr;33(4):411-3. doi: 10.1097/INF.0000000000000113.

PMID: 24378949

Similar articles Select item 24346602

64.Ganciclovir for the treatment of congenital cytomegalovirus: what are the side effects?

Gwee A, Curtis N, Connell TG, Garland S, Daley AJ.

Pediatr Infect Dis J. 2014 Jan;33(1):115. doi: 10.1097/INF.0000000000000032. No abstract available.

PMID: 24346602

Similar articles Select item 24252791

65.Bullous herpes zoster.

Wong KJ, Osowicki J, Seaby E, Curtis N, Gwee A.

J Pediatr. 2014 Mar;164(3):667. doi: 10.1016/j.jpeds.2013.10.026. No abstract available.

PMID: 24252791

Similar articles Select item 24210845

66.Streptococcal superantigens: categorization and clinical associations.

Commons RJ, Smeesters PR, Proft T, Fraser JD, Robins-Browne R, Curtis N.

Trends Mol Med. 2014 Jan;20(1):48-62. doi: 10.1016/j.molmed.2013.10.004. Review.

PMID: 24210845

Similar articles Select item 24139189

67.Ureaplasma--Are you sitting comfortably?

Gwee A, Curtis N.

J Infect. 2014 Jan;68 Suppl 1:S19-23. doi: 10.1016/j.jinf.2013.09.027. Review.

PMID: 24139189

Similar articles Select item 24098583

68.The contribution of non-conventional T cells and NK cells in the mycobacterial-specific IFNγ response in Bacille Calmette-Guérin (BCG)-immunized infants.

Zufferey C, Germano S, Dutta B, Ritz N, Curtis N.

PLoS One. 2013 Oct 3;8(10):e77334. doi: 10.1371/journal.pone.0077334.

PMID: 24098583 Free PMC Article

Similar articles Select item 24091192

69.Hot topics in infection and immunity in children--Papers from the 10th annual IIC meeting, Oxford, UK, 2012. Preface.

Curtis N, Pollard AJ, Finn A.

J Infect. 2014 Jan;68 Suppl 1:S1. doi: 10.1016/j.jinf.2013.09.008. No abstract available.

PMID: 24091192

Similar articles Select item 24067554

70.Sleep and infection: no snooze, you lose?

Bryant PA, Curtis N.

Pediatr Infect Dis J. 2013 Oct;32(10):1135-7. doi: 10.1097/INF.0b013e3182a4d610. Review. No abstract available.

PMID: 24067554

Similar articles Select item 24023612

71.Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility.

Chang CJ, Kuo HC, Chang JS, Lee JK, Tsai FJ, Khor CC, Chang LC, Chen SP, Ko TM, Liu YM, Chen YJ, Hong YM, Jang GY, Hibberd ML, Kuijpers T, Burgner D, Levin M, Burns JC, Davila S; International Kawasaki Disease Genetics Consortium.; Korean Kawasaki Disease Genetics Consortium.; Taiwan Kawasaki Disease Genetics Consortium., Chen YT, Chen CH, Wu JY, Lee YC.

PLoS One. 2013 Aug 30;8(8):e72037. doi: 10.1371/journal.pone.0072037.

PMID: 24023612 Free PMC Article

Similar articles Select item 24008747

72.Ureaplasma meningitis and subdural collections in a neonate.

Gwee A, Chinnappan M, Starr M, Curtis N, Pellicano A, Bryant P.

Pediatr Infect Dis J. 2013 Sep;32(9):1043-4. doi: 10.1097/INF.0b013e31829ae285. No abstract available.

PMID: 24008747

Similar articles Select item 23992183

73.Infants born in Australia to mothers from countries with a high prevalence of tuberculosis: to BCG or not to BCG?

Gwee A, Rodrigo R, Casalaz D, Ritz N, Curtis N.

Med J Aust. 2013 Sep 2;199(5):324-6. No abstract available.

PMID: 23992183

Similar articles Select item 23856714

74.Central line-associated bloodstream infection in children: an update on treatment.

Wolf J, Curtis N, Worth LJ, Flynn PM.

Pediatr Infect Dis J. 2013 Aug;32(8):905-10. doi: 10.1097/INF.0b013e3182996b6e. Review. No abstract available.

PMID: 23856714

Similar articles Select item 23838774

75.Antibiotic-resistant Gram-negative bacteremia in pediatric oncology patients--risk factors and outcomes.

Haeusler GM, Mechinaud F, Daley AJ, Starr M, Shann F, Connell TG, Bryant PA, Donath S, Curtis N.

Pediatr Infect Dis J. 2013 Jul;32(7):723-6. doi: 10.1097/INF.0b013e31828aebc8.

PMID: 23838774

Similar articles Select item 23838740

76.The antibiotic resistance and prescribing in European Children project: a neonatal and pediatric antimicrobial web-based point prevalence survey in 73 hospitals worldwide.

Versporten A, Sharland M, Bielicki J, Drapier N, Vankerckhoven V, Goossens H; ARPEC Project Group Members..

Pediatr Infect Dis J. 2013 Jun;32(6):e242-53. doi: 10.1097/INF.0b013e318286c612.

PMID: 23838740

Similar articles Select item 23661667

77.Question 1: what are the options for treating latent TB infection in children?

Gwee A, Coghlan B, Curtis N.

Arch Dis Child. 2013 Jun;98(6):468-74. doi: 10.1136/archdischild-2013-303876. Review. No abstract available.

PMID: 23661667

Similar articles Select item 23654054

78.Non-typhoidal Salmonella in children: microbiology, epidemiology and treatment.

Haeusler GM, Curtis N.

Adv Exp Med Biol. 2013;764:13-26. Review.

PMID: 23654054

Similar articles Select item 23647873

79.An update on Kawasaki disease II: clinical features, diagnosis, treatment and outcomes.

Yim D, Curtis N, Cheung M, Burgner D.

J Paediatr Child Health. 2013 Aug;49(8):614-23. doi: 10.1111/jpc.12221. Review.

PMID: 23647873

Similar articles Select item 23606714

80.To x-ray or not to x-ray? Screening asymptomatic children for pulmonary TB: a retrospective audit.

Gwee A, Pantazidou A, Ritz N, Tebruegge M, Connell TG, Cain T, Curtis N.

Arch Dis Child. 2013 Jun;98(6):401-4. doi: 10.1136/archdischild-2013-303672.

PMID: 23606714

Similar articles Select item 23583897

81.Non-specific effect of Bacille Calmette-Guérin vaccine on the immune response to routine immunisations.

Ritz N, Mui M, Balloch A, Curtis N.

Vaccine. 2013 Jun 26;31(30):3098-103. doi: 10.1016/j.vaccine.2013.03.059.

PMID: 23583897

Similar articles Select item 23572484

82.Heterologous ("nonspecific") and sex-differential effects of vaccines: epidemiology, clinical trials, and emerging immunologic mechanisms.

Flanagan KL, van Crevel R, Curtis N, Shann F, Levy O; Optimmunize Network..

Clin Infect Dis. 2013 Jul;57(2):283-9. doi: 10.1093/cid/cit209. Review.

PMID: 23572484 Free PMC Article

Similar articles Select item 23560706

83.Update on Kawasaki disease: epidemiology, aetiology and pathogenesis.

Yim D, Curtis N, Cheung M, Burgner D.

J Paediatr Child Health. 2013 Sep;49(9):704-8. doi: 10.1111/jpc.12172. Review.

PMID: 23560706

Similar articles Select item 23540883

84.Reply: Bacille Calmette-Guérin vaccine: innate immunity and nonspecific effects.

Ritz N, Casalaz D, Hanekom WA, Britton WJ, Dutta B, Donath S, Connell TG, Tebruegge M, Robins-Browne R, Curtis N.

Am J Respir Crit Care Med. 2013 Apr 1;187(7):779-80. No abstract available.

PMID: 23540883

Similar articles Select item 23492399

85.Prednisolone added to intravenous immunoglobulin treatment improves outcome in children with severe Kawasaki disease.

Curtis N.

Arch Dis Child Educ Pract Ed. 2013 Apr;98(2):77-8. doi: 10.1136/archdischild-2012-303413. No abstract available.

PMID: 23492399

Similar articles Select item 23438133

86.Central venous access device-related infections in patients with haemophilia.

Yeoh ZH, Furmedge J, Ekert J, Crameri J, Curtis N, Barnes C.

J Paediatr Child Health. 2013 Mar;49(3):242-5. doi: 10.1111/jpc.12112.

PMID: 23438133

Similar articles Select item 23075192

87.Tuberculosis in children.

Tebruegge M, Connell T, Curtis N.

N Engl J Med. 2012 Oct 18;367(16):1568; author reply 1569. doi: 10.1056/NEJMc1210173#SA2. No abstract available.

PMID: 23075192

Similar articles Select item 23019290

88.Interferon-γ release assays for the diagnosis of tuberculosis in children.

Tebruegge M, Connell TG, Ritz N, Curtis N.

Arch Dis Child. 2013 Mar;98(3):239-40. doi: 10.1136/archdischild-2012-302798. No abstract available.

PMID: 23019290

Similar articles Select item 22939686

89.Hip to the heart.

Haeusler GM, Goeman E, Cheung M, Creati M, Curtis N.

Lancet. 2012 Sep 1;380(9844):858. doi: 10.1016/S0140-6736(12)60573-X. No abstract available.

PMID: 22939686

Similar articles

Select item 22926211

90.A national prospective surveillance study of acute rheumatic fever in Australian children.

Noonan S, Zurynski YA, Currie BJ, McDonald M, Wheaton G, Nissen M, Curtis N, Isaacs D, Richmond P, Ramsay JM, Elliott EJ, Carapetis JR.

Pediatr Infect Dis J. 2013 Jan;32(1):e26-32. doi: 10.1097/INF.0b013e31826faeb3.

PMID: 22926211

Similar articles Select item 22911535

91.Ethanol lock therapy in pediatric hematology and oncology.

Wolf J, Shenep JL, Clifford V, Curtis N, Flynn PM.

Pediatr Blood Cancer. 2013 Jan;60(1):18-25. doi: 10.1002/pbc.24249. Review.

PMID: 22911535

Similar articles Select item 22855707

92.B cell memory to a serogroup C meningococcal conjugate vaccine in childhood and response to booster: little association with serum IgG antibody.

Perrett KP, Jin C, Clutterbuck E, John TM, Winter AP, Kibwana E, Yu LM, Curtis N, Pollard AJ.

J Immunol. 2012 Sep 1;189(5):2673-81. doi: 10.4049/jimmunol.1200451.

PMID: 22855707 Free Article

Similar articles Select item 22829867

93.A comparative analysis of polyfunctional T cells and secreted cytokines induced by Bacille Calmette-Guérin immunisation in children and adults.

Ritz N, Strach M, Yau C, Dutta B, Tebruegge M, Connell TG, Hanekom WA, Britton WJ, Robins-Browne R, Curtis N.

PLoS One. 2012;7(7):e37535. doi: 10.1371/journal.pone.0037535.

PMID: 22829867 Free PMC Article

Similar articles Select item 22686614

94.Invasive group a streptococcal disease: epidemiology, pathogenesis and management.

Steer AC, Lamagni T, Curtis N, Carapetis JR.

Drugs. 2012 Jun 18;72(9):1213-27. doi: 10.2165/11634180-000000000-00000. Review.

PMID: 22686614

Similar articles Select item 22592487

95.Adenovirus: an overview for pediatric infectious diseases specialists.

Tebruegge M, Curtis N.

Pediatr Infect Dis J. 2012 Jun;31(6):626-7. doi: 10.1097/INF.0b013e318250b066. Review. No abstract available.

PMID: 22592487

Similar articles Select item 22327874

96.The role of Panton-Valentine leukocidin in Staphylococcus aureus musculoskeletal infections in children.

Ritz N, Curtis N.

Pediatr Infect Dis J. 2012 May;31(5):514-8. doi: 10.1097/INF.0b013e31824f18cb. Review.

PMID: 22327874

Similar articles Select item 22241920

97.Question 1. Do febrile convulsions cause CSF pleocytosis?

Haeusler GM, Tebruegge M, Curtis N.

Arch Dis Child. 2012 Feb;97(2):172-5. doi: 10.1136/archdischild-2011-301223. Review. No abstract available.

PMID: 22241920

Similar articles

Select item 22155145

98.To TST or not to TST: is tuberculin skin testing necessary before BCG immunisation in children?

Ritz N, Tebruegge M, Camacho-Badilla K, Haeusler GM, Connell TG, Curtis N.

Vaccine. 2012 Feb 14;30(8):1434-6. doi: 10.1016/j.vaccine.2011.11.099. Review.

PMID: 22155145

Similar articles Select item 22125046

99.Mycobacterium marinum infection.

Tebruegge M, Curtis N.

Adv Exp Med Biol. 2011;719:201-10. doi: 10.1007/978-1-4614-0204-6_17. Review. No abstract available.

PMID: 22125046

Similar articles Select item 22096488

100.The age-related risk of co-existing meningitis in children with urinary tract infection.

Tebruegge M, Pantazidou A, Clifford V, Gonis G, Ritz N, Connell T, Curtis N.

PLoS One. 2011;6(11):e26576. doi: 10.1371/journal.pone.0026576.

PMID: 22096488 Free PMC Article

Similar articles Select item 22071384

101.The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial.

Ritz N, Dutta B, Donath S, Casalaz D, Connell TG, Tebruegge M, Robins-Browne R, Hanekom WA, Britton WJ, Curtis N.

Am J Respir Crit Care Med. 2012 Jan 15;185(2):213-22. doi: 10.1164/rccm.201104-0714OC.

PMID: 22071384

Similar articles Select item 21905000

102.Disruption of vascular homeostasis in patients with Kawasaki disease: involvement of vascular endothelial growth factor and angiopoietins.

Breunis WB, Davila S, Shimizu C, Oharaseki T, Takahashi K, van Houdt M, Khor CC, Wright VJ, Levin M, Burns JC, Burgner D, Hibberd ML, Kuijpers TW; International Kawasaki Disease Genetics Consortium..

Arthritis Rheum. 2012 Jan;64(1):306-15. doi: 10.1002/art.33316.

PMID: 21905000 Free Article

Similar articles Select item 21903602

103.Kawasaki disease as a cause of encephalitis.

Burgner D, Curtis N.

Arch Dis Child. 2011 Oct;96(10):988-9. doi: 10.1136/archdischild-2011-300613. No abstract available.

PMID: 21903602

Similar articles Select item 21655321

104.Technical variability is greater than biological variability in a microarray experiment but both are outweighed by changes induced by stimulation.

Bryant PA, Smyth GK, Robins-Browne R, Curtis N.

PLoS One. 2011;6(5):e19556. doi: 10.1371/journal.pone.0019556.

PMID: 21655321 Free PMC Article

Similar articles Select item 21575296

105.Absence of interferon-gamma release assay conversion following tuberculin skin testing.

Ritz N, Yau C, Connell TG, Tebruegge M, Leslie D, Curtis N.

Int J Tuberc Lung Dis. 2011 Jun;15(6):767-9. doi: 10.5588/ijtld.10.0339.

PMID: 21575296

Similar articles Select item 21571869

106.Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease.

Khor CC, Davila S, Shimizu C, Sheng S, Matsubara T, Suzuki Y, Newburger JW, Baker A, Burgner D, Breunis W, Kuijpers T, Wright VJ, Levin M, Hibberd ML, Burns JC; US and International Kawasaki Disease Genetics Consortia..

J Med Genet. 2011 Jul;48(7):467-72. doi: 10.1136/jmg.2010.086611.

PMID: 21571869

Similar articles Select item 21562337

107.Question 1. How common is co-existing meningitis in infants with urinary tract infection?

Tebruegge M, Pantazidou A, Curtis N.

Arch Dis Child. 2011 Jun;96(6):602-6. doi: 10.1136/adc.2011.215277. Review. No abstract available.

PMID: 21562337

Similar articles Select item 21491177

108.Tuberculous dactylitis--an easily missed diagnosis.

Ritz N, Connell TG, Tebruegge M, Johnstone BR, Curtis N.

Eur J Clin Microbiol Infect Dis. 2011 Nov;30(11):1303-10. doi: 10.1007/s10096-011-1239-5. Review.

PMID: 21491177

Similar articles Select item 21407040

109.Oral ivermectin for the treatment of pediculosis capitis.

Tebruegge M, Pantazidou A, Curtis N.

Pediatr Infect Dis J. 2011 Apr;30(4):362-3. doi: 10.1097/INF.0b013e31820ea00c. No abstract available.

PMID: 21407040

Similar articles Select item 21120734

110.A practical approach to eosinophilia in a child arriving or returning from the tropics.

Bryant P, Curtis N.

Adv Exp Med Biol. 2011;697:289-99. doi: 10.1007/978-1-4419-7185-2_20. Review. No abstract available.

PMID: 21120734

Similar articles Select item 20980248

111.The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children.

Connell TG, Tebruegge M, Ritz N, Bryant P, Curtis N.

Thorax. 2011 Mar;66(3):263-4; author reply 265. doi: 10.1136/thx.2010.143396. No abstract available.

PMID: 20980248

Similar articles Select item 20796180

112.Perception, attitudes and knowledge regarding the 2009 swine-origin influenza A (H1N1) virus pandemic among health-care workers in Australia.

Tebruegge M, Pantazidou A, Ritz N, Connell T, Bryant P, Donath S, Curtis N.

J Paediatr Child Health. 2010 Nov;46(11):673-9. doi: 10.1111/j.1440-1754.2010.01820.x.

PMID: 20796180

Similar articles Select item 20688849

113.What's bugging you? An update on the treatment of head lice infestation.

Tebruegge M, Pantazidou A, Curtis N.

Arch Dis Child Educ Pract Ed. 2011 Feb;96(1):2-8. doi: 10.1136/adc.2009.178038. Review.

PMID: 20688849

Similar articles Select item 20679608

114.Lessons learned from an unusual presentation of CD3+, CD56- T-cell large granular lymphocyte leukemia.

Lee RJ, Ritz N, Chan AC, Berzins SP, Came N, Curtis N, Lim A, Harrison SJ.

J Clin Oncol. 2010 Oct 1;28(28):e498-502. doi: 10.1200/JCO.2010.29.1898. No abstract available.

PMID: 20679608

Similar articles Select item 20595171

115.Discordance between TSTs and IFN-gamma release assays: the role of NTM and the relevance of mycobacterial sensitins.

Tebruegge M, Connell T, Ritz N, Bryant PA, Curtis N.

Eur Respir J. 2010 Jul;36(1):214-5; author reply 215-6. doi: 10.1183/09031936.00025510. No abstract available.

PMID: 20595171 Free Article

Similar articles Select item 20546101

116.Antibiotic susceptibility patterns of Staphylococcus aureus isolates from Australian children.

Wolf J, Daley AJ, Tilse MH, Nimmo GR, Bell S, Howell AJ, Keil AD, Lawrence A, Curtis N.

J Paediatr Child Health. 2010 Jul;46(7-8):404-11. doi: 10.1111/j.1440-1754.2010.01751.x.

PMID: 20546101

Similar articles Select item 20541959

117.Mycobacterium marinum infection following kayaking injury.

Tebruegge M, Connell T, Ritz N, Orchard D, Curtis N.

Int J Infect Dis. 2010 Sep;14 Suppl 3:e305-6. doi: 10.1016/j.ijid.2010.02.2246. No abstract available.

PMID: 20541959 Free Article

Similar articles Select item 20507549

118.Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children.

Connell TG, Davies MA, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Beatty D, Nicol MP, Curtis N, Eley B.

BMC Infect Dis. 2010 May 27;10:138. doi: 10.1186/1471-2334-10-138.

PMID: 20507549 Free PMC Article

Similar articles Select item 20459323

119.Antibody persistence after serogroup C meningococcal conjugate immunization of United Kingdom primary-school children in 1999-2000 and response to a booster: a phase 4 clinical trial.

Perrett KP, Winter AP, Kibwana E, Jin C, John TM, Yu LM, Borrow R, Curtis N, Pollard AJ.

Clin Infect Dis. 2010 Jun 15;50(12):1601-10. doi: 10.1086/652765.

PMID: 20459323

Similar articles Select item 20458257

120.Clinical and microbiologic features associated with novel swine-origin influenza A pandemic 2009 (H1N1) virus in children: a prospective cohort study.

Bryant PA, Tebruegge M, Papadakis G, Clarke C, Barnett P, Daley AJ, South M, Curtis N.

Pediatr Infect Dis J. 2010 Aug;29(8):694-8. doi: 10.1097/INF.0b013e3181de4b9c.

PMID: 20458257

Similar articles Select item 20204763

121.Adenovirus infection in the immunocompromised host.

Tebruegge M, Curtis N.

Adv Exp Med Biol. 2010;659:153-74. doi: 10.1007/978-1-4419-0981-7_13. Review. No abstract available.

PMID: 20204763

Similar articles

Select item 20194265

122.Picture of the month. Sinusitis complicated by epidural abscess.

Tebruegge M, Curtis N, Wallace D, Starr M, Bryant P.

Arch Pediatr Adolesc Med. 2010 Mar;164(3):289-91. doi: 10.1001/archpediatrics.2010.2-a. No abstract available.

PMID: 20194265

Similar articles Select item 20190616

123.Indeterminate interferon-gamma release assay results in children.

Connell TG, Tebruegge M, Ritz N, Bryant PA, Leslie D, Curtis N.

Pediatr Infect Dis J. 2010 Mar;29(3):285-6. doi: 10.1097/INF.0b013e3181c4822f. No abstract available.

PMID: 20190616

Similar articles Select item 20040690

124.Question 3: can pneumonia caused by penicillin-resistant Streptococcus pneumoniae be treated with penicillin?

Clifford V, Tebruegge M, Vandeleur M, Curtis N.

Arch Dis Child. 2010 Jan;95(1):73-7. doi: 10.1136/adc.2009.171611. Review. No abstract available.

PMID: 20040690

Similar articles

Select item 19910840

125.Ureaplasma: pathogen or passenger in neonatal meningitis?

Clifford V, Tebruegge M, Everest N, Curtis N.

Pediatr Infect Dis J. 2010 Jan;29(1):60-4. doi: 10.1097/INF.0b013e3181b21016.

PMID: 19910840

Similar articles Select item 19786433

126.Estimating blood loss: comparative study of the accuracy of parents and health care professionals.

Tebruegge M, Misra I, Pantazidou A, Padhye A, Maity S, Dwarakanathan B, Donath S, Curtis N, Nerminathan V.

Pediatrics. 2009 Oct;124(4):e729-36. doi: 10.1542/peds.2009-0592.

PMID: 19786433

Similar articles Select item 19687714

127.Monkey bites in travelers: should we think of herpes B virus?

Ritz N, Curtis N, Buttery J, Babl FE.

Pediatr Emerg Care. 2009 Aug;25(8):529-31. doi: 10.1097/PEC.0b013e3181b0a45c.

PMID: 19687714

Similar articles Select item 19654063

128.Too much of a good thing: management of BCG vaccine overdose.

Ritz N, Tebruegge M, Streeton J, Curtis N.

Vaccine. 2009 Sep 18;27(41):5562-4. doi: 10.1016/j.vaccine.2009.07.043.

PMID: 19654063

Similar articles Select item 19633530

129.Interferon-gamma release assays for the diagnosis of tuberculosis.

Connell T, Tebruegge M, Ritz N, Curtis N.

Pediatr Infect Dis J. 2009 Aug;28(8):758-9. doi: 10.1097/INF.0b013e3181b00dbf. No abstract available.

PMID: 19633530

Similar articles Select item 19542068

130.Towards evidence based medicine for paediatricians. How effective is varicella-zoster immunoglobulin (VZIG) in preventing chickenpox in neonates following perinatal exposure?

Tebruegge M, Pantazidou A, Curtis N.

Arch Dis Child. 2009 Jul;94(7):559-61. doi: 10.1136/adc.2008.154542. Review. No abstract available.

PMID: 19542068

Similar articles Select item 19540166

131.Mapping the global use of different BCG vaccine strains.

Ritz N, Curtis N.

Tuberculosis (Edinb). 2009 Jul;89(4):248-51. doi: 10.1016/j.tube.2009.03.002.

PMID: 19540166

Similar articles Select item 19515707

132.A 2 year old girl with fever, cough, and tachypnoea.

Tebruegge M, Ritz N, Connell T, Curtis N.

BMJ. 2009 Jun 10;338:b1210. doi: 10.1136/bmj.b1210. No abstract available.

PMID: 19515707

Similar articles Select item 19401934

133.Bacterial tracheitis: a multi-centre perspective.

Tebruegge M, Pantazidou A, Thorburn K, Riordan A, Round J, De Munter C, Walters S, Curtis N.

Scand J Infect Dis. 2009;41(8):548-57. doi: 10.1080/00365540902913478. Review.

PMID: 19401934

Similar articles Select item 19303380

134.Enterovirus infections in neonates.

Tebruegge M, Curtis N.

Semin Fetal Neonatal Med. 2009 Aug;14(4):222-7. doi: 10.1016/j.siny.2009.02.002. Review.

PMID: 19303380

Similar articles Select item 19287300

135.Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay.

Davies MA, Connell T, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Eley B, Beatty D, Curtis N, Nicol MP.

AIDS. 2009 May 15;23(8):961-9. doi: 10.1097/QAD.0b013e32832956ad.

PMID: 19287300 Free PMC Article

Similar articles Select item 19212463

136.Detection of gene expression in an individual cell type within a cell mixture using microarray analysis.

Bryant PA, Smyth GK, Robins-Browne R, Curtis N.

PLoS One. 2009;4(2):e4427. doi: 10.1371/journal.pone.0004427.

PMID: 19212463 Free PMC Article

Similar articles Select item 19204317

137.Some of the people, some of the time: susceptibility to acute rheumatic fever.

Bryant PA, Robins-Browne R, Carapetis JR, Curtis N.

Circulation. 2009 Feb 10;119(5):742-53. doi: 10.1161/CIRCULATIONAHA.108.792135. Review.

PMID: 19204317 Free Article

Similar articles Select item 19132087

138.A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease.

Burgner D, Davila S, Breunis WB, Ng SB, Li Y, Bonnard C, Ling L, Wright VJ, Thalamuthu A, Odam M, Shimizu C, Burns JC, Levin M, Kuijpers TW, Hibberd ML; International Kawasaki Disease Genetics Consortium..

PLoS Genet. 2009 Jan;5(1):e1000319. doi: 10.1371/journal.pgen.1000319.

PMID: 19132087 Free PMC Article

Similar articles Select item 19106777

139.Necrotizing epiglottitis in an infant: an unusual first presentation of human immunodeficiency virus infection.

Tebruegge M, Connell T, Kong K, Marks M, Curtis N.

Pediatr Infect Dis J. 2009 Feb;28(2):164-6. doi: 10.1097/INF.0b013e318187a869.

PMID: 19106777

Similar articles Select item 18955515

140.Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics.

Ritz N, Tebruegge M, Connell TG, Sievers A, Robins-Browne R, Curtis N.

Antimicrob Agents Chemother. 2009 Jan;53(1):316-8. doi: 10.1128/AAC.01302-08.

PMID: 18955515 Free PMC Article

Similar articles Select item 18833024

141.Human immunodeficiency virus-infected boy with Stevens-Johnson syndrome caused by nevirapine.

Tebruegge M, Ritz N, Connell T, Curtis N.

Pediatr Infect Dis J. 2008 Nov;27(11):1041-2. doi: 10.1097/INF.0b013e318185fb3a. No abstract available.

PMID: 18833024

Similar articles Select item 18809552

142.Superantigen genes in group A streptococcal isolates and their relationship with emm types.

Commons R, Rogers S, Gooding T, Danchin M, Carapetis J, Robins-Browne R, Curtis N.

J Med Microbiol. 2008 Oct;57(Pt 10):1238-46. doi: 10.1099/jmm.0.2008/001156-0.

PMID: 18809552

Similar articles Select item 18804139

143.To BCG or not to BCG? Preventing travel-associated tuberculosis in children.

Ritz N, Connell TG, Curtis N.

Vaccine. 2008 Nov 5;26(47):5905-10. doi: 10.1016/j.vaccine.2008.08.061. Review.

PMID: 18804139

Similar articles Select item 18625686

144.Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis.

Tebruegge M, Curtis N.

Clin Microbiol Rev. 2008 Jul;21(3):519-37. doi: 10.1128/CMR.00009-08. Review.

PMID: 18625686 Free PMC Article

Similar articles Select item 18616602

145.Influence of BCG vaccine strain on the immune response and protection against tuberculosis.

Ritz N, Hanekom WA, Robins-Browne R, Britton WJ, Curtis N.

FEMS Microbiol Rev. 2008 Aug;32(5):821-41. doi: 10.1111/j.1574-6976.2008.00118.x. Review.

PMID: 18616602 Free Article

Similar articles Select item 18612425

146.A three-way comparison of tuberculin skin testing, QuantiFERON-TB gold and T-SPOT.TB in children.

Connell TG, Ritz N, Paxton GA, Buttery JP, Curtis N, Ranganathan SC.

PLoS One. 2008 Jul 9;3(7):e2624. doi: 10.1371/journal.pone.0002624.

PMID: 18612425 Free PMC Article

Similar articles Select item 23495659

147.Diagnosis and treatment of invasive group A streptococcal infections.

Steer AC, Curtis N, Carapetis JR.

Expert Opin Med Diagn. 2008 Mar;2(3):289-301. doi: 10.1517/17530059.2.3.289.

PMID: 23495659

Similar articles Select item 18193665

148.What the paediatrician needs to know when pandemic influenza arrives in clinical practice.

Ritz N, Curtis N.

Adv Exp Med Biol. 2008;609:164-84. doi: 10.1007/978-0-387-73960-1_13. Review. No abstract available.

PMID: 18193665

Similar articles Select item 18162951

149.Brain abscess secondary to dental braces.

Wolf J, Curtis N.

Pediatr Infect Dis J. 2008 Jan;27(1):84-5.

PMID: 18162951

Similar articles Select item 17974731

150.Burden of acute sore throat and group A streptococcal pharyngitis in school-aged children and their families in Australia.

Danchin MH, Rogers S, Kelpie L, Selvaraj G, Curtis N, Carlin JB, Nolan TM, Carapetis JR.

Pediatrics. 2007 Nov;120(5):950-7.

PMID: 17974731

Similar articles Select item 17683011

151.Liposomal amphotericin B trial marred by conclusions.

Wolf J, Buttery J, Daley AJ, Hanieh S, Shann F, Starr M, Curtis N.

Clin Infect Dis. 2007 Sep 1;45(5):667-8; author reply 668-9. No abstract available.

PMID: 17683011

Similar articles Select item 17636756

152.Antibiotics for whooping cough (pertussis).

Altunaiji S, Kukuruzovic R, Curtis N, Massie J.

Cochrane Database Syst Rev. 2007 Jul 18;(3):CD004404. Review.

PMID: 17636756

Similar articles Select item 17547544

153.The epidemiology of invasive group A streptococcal disease in Victoria, Australia.

O'Grady KA, Kelpie L, Andrews RM, Curtis N, Nolan TM, Selvaraj G, Passmore JW, Oppedisano F, Carnie JA, Carapetis JR.

Med J Aust. 2007 Jun 4;186(11):565-9.

PMID: 17547544

Similar articles Select item 17522328

154.Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector.

Connell TG, Shey MS, Seldon R, Rangaka MX, van Cutsem G, Simsova M, Marcekova Z, Sebo P, Curtis N, Diwakar L, Meintjes GA, Leclerc C, Wilkinson RJ, Wilkinson KA.

Clin Vaccine Immunol. 2007 Jul;14(7):847-54.

PMID: 17522328 Free PMC Article

Similar articles Select item 17475690

155.Physicians' perception of pandemic influenza.

Curtis N, Pollard AJ.

Arch Dis Child. 2007 Oct;92(10):938. No abstract available.

PMID: 17475690 Free PMC Article

Similar articles Select item 17473088

156.How reliable is a negative blood culture result? Volume of blood submitted for culture in routine practice in a children's hospital.

Connell TG, Rele M, Cowley D, Buttery JP, Curtis N.

Pediatrics. 2007 May;119(5):891-6.

PMID: 17473088

Similar articles Select item 17471432

157.Strain prevalence, rather than innate virulence potential, is the major factor responsible for an increase in serious group A streptococcus infections.

Rogers S, Commons R, Danchin MH, Selvaraj G, Kelpie L, Curtis N, Robins-Browne R, Carapetis JR.

J Infect Dis. 2007 Jun 1;195(11):1625-33.

PMID: 17471432

Similar articles Select item 17009902

158.QuantiFERON-TB Gold: state of the art for the diagnosis of tuberculosis infection?

Connell TG, Rangaka MX, Curtis N, Wilkinson RJ.

Expert Rev Mol Diagn. 2006 Sep;6(5):663-77. Review.

PMID: 17009902

Similar articles Select item 16905194

159.Interferon-gamma release assays in children--no better than tuberculin skin testing?

Ranganathan S, Connell T, Curtis N.

J Infect. 2007 Apr;54(4):412-3; author reply 414-5. No abstract available.

PMID: 16905194

Similar articles Select item 16802617

160.Viral haemorrhagic fevers caused by Lassa, Ebola and Marburg viruses.

Curtis N.

Adv Exp Med Biol. 2006;582:35-44. Review. No abstract available.

PMID: 16802617

Similar articles Select item 16753492

161.Skin ulceration: what lies beneath.

Millay OJ, Connell TG, Bryant PA, Curtis N.

Lancet. 2006 Jun 3;367(9525):1874. No abstract available.

PMID: 16753492

Similar articles Select item 16737484

162.Successful treatment of cytomegalovirus-associated haemophagocytic syndrome following paediatric orthotopic liver transplantation.

Hardikar W, Pang K, Al-Hebbi H, Curtis N, Couper R.

J Paediatr Child Health. 2006 Jun;42(6):389-91.

PMID: 16737484

Similar articles Select item 16719750

163.B-cell antigen D8/17 is a marker of rheumatic fever susceptibility in Aboriginal Australians and can be tested in remote settings.

Harrington Z, Visvanathan K, Skinner NA, Curtis N, Currie BJ, Carapetis JR.

Med J Aust. 2006 May 15;184(10):507-10.

PMID: 16719750

Similar articles Select item 16652300

164.Early detection of perinatal tuberculosis using a whole blood interferon-gamma release assay.

Connell T, Bar-Zeev N, Curtis N.

Clin Infect Dis. 2006 Jun 1;42(11):e82-5.

PMID: 16652300

Similar articles Select item 16601088

165.Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children.

Connell TG, Curtis N, Ranganathan SC, Buttery JP.

Thorax. 2006 Jul;61(7):616-20.

PMID: 16601088 Free PMC Article

Similar articles Select item 16411090

166.Syphilis returns to the suburbs.

Hargrove A, Curtis N.

Eur J Pediatr. 2006 May;165(5):290-2.

PMID: 16411090

Similar articles Select item 16244213

167.Cytomegalovirus remains viable in naturally infected breast milk despite being frozen for 10 days.

Curtis N, Chau L, Garland S, Tabrizi S, Alexander R, Morley CJ.

Arch Dis Child Fetal Neonatal Ed. 2005 Nov;90(6):F529-30.

PMID: 16244213 Free PMC Article

Similar articles Select item 16184210

168.Fever in children.

Pearce C, Curtis N.

Aust Fam Physician. 2005 Sep;34(9):769-71. Review.

PMID: 16184210 Free Article

Similar articles Select item 16107074

169.How to interpret a CSF--the art and the science.

Connell T, Curtis N.

Adv Exp Med Biol. 2005;568:199-216. No abstract available.

PMID: 16107074

Similar articles Select item 15988608

170.Variations in the protective immune response against streptococcal superantigens in populations of different ethnicity.

Yang LP, Eriksson BK, Harrington Z, Curtis N, Lang S, Currie BJ, Fraser JD, Proft T.

Med Microbiol Immunol. 2006 Mar;195(1):37-43.

PMID: 15988608

Similar articles Select item 15790316

171.The diagnosis and management of Kawasaki disease.

Royle J, Burgner D, Curtis N.

J Paediatr Child Health. 2005 Mar;41(3):87-93. Review.

PMID: 15790316

Similar articles Select item 15750453

172.Analysis of respiratory viral coinfection and cytomegalovirus coisolation in pediatric inpatients.

Fuller DG, Davie G, Lamb D, Carlin JB, Curtis N.

Pediatr Infect Dis J. 2005 Mar;24(3):195-200.

PMID: 15750453

Similar articles Select item 15721480

173.Skin ulcers in a returned traveller.

Connell TG, Rele M, Daley AJ, Curtis N.

Lancet. 2005 Feb 19-25;365(9460):726. No abstract available.

PMID: 15721480

Similar articles Select item 15674946

174.Antibiotics for whooping cough (pertussis).

Altunaiji S, Kukuruzovic R, Curtis N, Massie J.

Cochrane Database Syst Rev. 2005 Jan 25;(1):CD004404. Review. Update in: Cochrane Database Syst Rev. 2007;(3):CD004404.

PMID: 15674946

Similar articles Select item 15639303

175.Suppurative sequelae of symbiosis.

Steer A, Daley AJ, Curtis N.

Lancet. 2005 Jan 8-14;365(9454):188. No abstract available.

PMID: 15639303

Similar articles Select item 15542199

176.The burden and cost of hospitalised varicella and zoster in Australian children.

Carapetis JR, Russell DM, Curtis N.

Vaccine. 2004 Dec 21;23(6):755-61.

PMID: 15542199

Similar articles Select item 15250533

177.Kawasaki disease and toxic shock syndrome--at last the etiology is clear?

Curtis N.

Adv Exp Med Biol. 2004;549:191-200. Review.

PMID: 15250533

Similar articles Select item 15243039

178.Prospective study of a real-time PCR that is highly sensitive, specific, and clinically useful for diagnosis of meningococcal disease in children.

Bryant PA, Li HY, Zaia A, Griffith J, Hogg G, Curtis N, Carapetis JR.

J Clin Microbiol. 2004 Jul;42(7):2919-25.

PMID: 15243039 Free PMC Article

Similar articles Select item 15232181

179.The burden of group A streptococcal pharyngitis in Melbourne families.

Danchin MH, Rogers S, Selvaraj G, Kelpie L, Rankin P, Vorich R, Howson M, Carlin JB, Curtis N, Nolan TM, Carapetis JR.

Indian J Med Res. 2004 May;119 Suppl:144-7.

PMID: 15232181

Similar articles Select item 15184494

180.Fatal case of toxic shock-like syndrome due to group C streptococcus associated with superantigen exotoxin.

Korman TM, Boers A, Gooding TM, Curtis N, Visvanathan K.

J Clin Microbiol. 2004 Jun;42(6):2866-9. Review.

PMID: 15184494 Free PMC Article

Similar articles Select item 15173834

181.Sick and tired: Does sleep have a vital role in the immune system?

Bryant PA, Trinder J, Curtis N.

Nat Rev Immunol. 2004 Jun;4(6):457-67. Review. No abstract available.

PMID: 15173834

Similar articles Select item 15151589

182.Fever in a returned traveller.

Fuller D, Hasnat M, Marks MK, Curtis N.

J Paediatr Child Health. 2004 May-Jun;40(5-6):315-6.

PMID: 15151589

Similar articles Select item 14986123

183.Neonatal coxsackie B virus infection-a treatable disease?

Bryant PA, Tingay D, Dargaville PA, Starr M, Curtis N.

Eur J Pediatr. 2004 Apr;163(4-5):223-8.

PMID: 14986123

Similar articles Select item 14871635

184.Chips with everything: DNA microarrays in infectious diseases.

Bryant PA, Venter D, Robins-Browne R, Curtis N.

Lancet Infect Dis. 2004 Feb;4(2):100-11. Review.

PMID: 14871635

Similar articles Select item 14738571

185.Antibiotic treatment for bacterial meningitis in children in developing countries.

Fuller DG, Duke T, Shann F, Curtis N.

Ann Trop Paediatr. 2003 Dec;23(4):233-53. Review.

PMID: 14738571

Similar articles Select item 14718005

186.Cephalosporin resistant urinary tract infections in young children.

Mehr SS, Powell CV, Curtis N.

J Paediatr Child Health. 2004 Jan-Feb;40(1-2):48-52.

PMID: 14718005

Similar articles Select item 14659895

187.Rapid analysis of the Vbeta repertoire of CD4 and CD8 T lymphocytes in whole blood.

MacIsaac C, Curtis N, Cade J, Visvanathan K.

J Immunol Methods. 2003 Dec;283(1-2):9-15.

PMID: 14659895

Similar articles Select item 12877633

188.The management of bacterial meningitis in children.

Duke T, Curtis N, Fuller DG.

Expert Opin Pharmacother. 2003 Aug;4(8):1227-40. Review.

PMID: 12877633

Similar articles Select item 12856055

189.Evidence on the use of paracetamol in febrile children.

Russell FM, Shann F, Curtis N, Mulholland K.

Bull World Health Organ. 2003;81(5):367-72. Review.

PMID: 12856055 Free PMC Article

Similar articles Select item 12737900

190.Return of Haemophilus influenzae type b infections.

Curtis N, Duke T, Fuller D, Shann F.

Lancet. 2003 May 3;361(9368):1564. No abstract available.

PMID: 12737900

Similar articles Select item 12580755

191.Pertussis: adults as a source in healthcare settings.

Massie RJ, Altunaji S, Kukurozovic R, Curtis N.

Med J Aust. 2003 Feb 17;178(4):191; author reply 191. No abstract available.

PMID: 12580755

Similar articles Select item 12506954

192.Recurrent crepitant cellulitis caused by Clostridium perfringens.

Bryant P, Carapetis J, Matussek J, Curtis N.

Pediatr Infect Dis J. 2002 Dec;21(12):1173-4.

PMID: 12506954

Similar articles Select item 12463383

193.Auditory- and somatosensory-evoked potentials in cerebral malaria and anaesthesia: a comparison.

Thornton C, Heyderman RS, Thorniley M, Curtis N, Mielke J, Pasvol G, Newton DE.

Eur J Anaesthesiol. 2002 Oct;19(10):717-26.

PMID: 12463383

Similar articles Select item 12405896

194.Treatment of sore throat in light of the Cochrane verdict: is the jury still out?

Danchin MH, Curtis N, Nolan TM, Carapetis JR.

Med J Aust. 2002 Nov 4;177(9):512-5.

PMID: 12405896

Similar articles Select item 12400533

195.The "surreptitious Staphylococcus": Staphylococcus lugdunensis endocarditis in a child.

Sotutu V, Carapetis J, Wilkinson J, Davis A, Curtis N.

Pediatr Infect Dis J. 2002 Oct;21(10):984-6.

PMID: 12400533

Similar articles Select item 12394816

196.Clinical implications of inducible beta-lactamase activity in Gram-negative bacteremia in children.

Boyle RJ, Curtis N, Kelly N, Garland SM, Carapetis JR.

Pediatr Infect Dis J. 2002 Oct;21(10):935-40.

PMID: 12394816

Similar articles Select item 12193509

197.Cytomegalovirus transmission from breast milk in premature babies: does it matter?

Bryant P, Morley C, Garland S, Curtis N.

Arch Dis Child Fetal Neonatal Ed. 2002 Sep;87(2):F75-7. Review.

PMID: 12193509 Free PMC Article

Similar articles Select item 12173997

198.Duration of antibiotics in children with osteomyelitis and septic arthritis.

Vinod MB, Matussek J, Curtis N, Graham HK, Carapetis JR.

J Paediatr Child Health. 2002 Aug;38(4):363-7.

PMID: 12173997

Similar articles Select item 12047704

199.Mycobacterium ulcerans infection diagnosed by polymerase chain reaction.

Russell FM, Starr M, Hayman J, Curtis N, Johnson PD.

J Paediatr Child Health. 2002 Jun;38(3):311-3.

PMID: 12047704

Similar articles Select item 11734717

200.Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child.

Bryant P, Sasadeusz J, Carapetis J, Waters K, Curtis N.

Pediatr Infect Dis J. 2001 Nov;20(11):1083-6.

PMID: 11734717

Similar articles

201.MMR immunisation. True anaphylaxis to MMR vaccine is extremely rare.

Carapetis JR, Curtis N, Royle J.

BMJ. 2001 Oct 13;323(7317):869. No abstract available.

PMID: 11683165 Free PMC Article

Similar articles Select item 11389507

202.Severe Bordetella holmesii infection in a previously healthy adolescent confirmed by gene sequence analysis.

Russell FM, Davis JM, Whipp MJ, Janssen PH, Ward PB, Vyas JR, Starr M, Sawyer SM, Curtis N.

Clin Infect Dis. 2001 Jul 1;33(1):129-30.

PMID: 11389507

Similar articles Select item 11376819

203.Aspergillus laryngotracheobronchial infection in a 6-year-old girl following bone marrow transplantation.

Barnes C, Berkowitz R, Curtis N, Waters K.

Int J Pediatr Otorhinolaryngol. 2001 May 31;59(1):59-62.

PMID: 11376819

Similar articles Select item 10897363

204.Adults with cerebral malaria do not have sensory evoked responses typical of deep general anaesthesia.

Heyderman RS, Thornton C, Mielke J, Curtis N, Thorniley MS, Green CJ, Newton DE, Pasvol G.

Trans R Soc Trop Med Hyg. 2000 Mar-Apr;94(2):182-4. No abstract available.

PMID: 10897363

Similar articles Select item 9529634

205.Kawasaki disease thirty years on.

Curtis N, Levin M.

Curr Opin Pediatr. 1998 Feb;10(1):24-33. Review.

PMID: 9529634

Similar articles

Select item 9270443

206.Kawasaki disease.

Curtis N.

BMJ. 1997 Aug 9;315(7104):322-3. No abstract available.

PMID: 9270443 Free PMC Article

Similar articles Select item 9174577

207.Musculoskeletal side-effects of varicella.

Curtis N, Jacobs M, Sriskandan S.

Lancet. 1997 May 31;349(9065):1623-4. No abstract available.

PMID: 9174577

Similar articles Select item 9014616

208.Non-steroidal anti-inflammatory drugs may predispose to invasive group A streptococcal infections.

Curtis N.

Arch Dis Child. 1996 Dec;75(6):547. No abstract available.

PMID: 9014616 Free PMC Article

Similar articles Select item 8704543

209.Potentially lethal bacterial infection associated with varicella zoster virus.

Pollard AJ, Isaacs A, Hermione Lyall EG, Curtis N, Lee K, Walters S, Levin M.

BMJ. 1996 Aug 3;313(7052):283-5. No abstract available.

PMID: 8704543 Free PMC Article

Similar articles Select item 7763061

210.Evidence for a superantigen mediated process in Kawasaki disease.

Curtis N, Zheng R, Lamb JR, Levin M.

Arch Dis Child. 1995 Apr;72(4):308-11.

PMID: 7763061 Free PMC Article

Similar articles Select item 7905127

211.Toxic shock syndrome toxin-secreting Staphylococcus aureus in Kawasaki syndrome.

Curtis N, Chan B, Levin M.

Lancet. 1994 Jan 29;343(8892):299. No abstract available.

PMID: 7905127

Similar articles Select item 8329024

212.Anti-TNF therapy inhibits fever in cerebral malaria.

Kwiatkowski D, Molyneux ME, Stephens S, Curtis N, Klein N, Pointaire P, Smit M, Allan R, Brewster DR, Grau GE, et al.

Q J Med. 1993 Feb;86(2):91-8.

PMID: 8329024

Similar articles Select item 1720819

213.Cyclical vomiting and hypertension with dermatographism and histamine release.

Thomas AG, Curtis N, Walker-Smith A.

J R Soc Med. 1991 Oct;84(10):629. No abstract available.

PMID: 1720819 Free PMC Article

Similar articles

Research Projects

This Research Group doesn't currently have any projects



Faculty Research Themes

Child Health, Infection and Immunology

School Research Themes

Child Health in Medicine



Key Contact

For further information about this research, please contact Professor Nigel Curtis