Ophthalmic Epidemiology Group
Led by Professor Mingguang He, the Ophthalmic Epidemiology group conduct clinical and epidemiologic research in eye and vision-related diseases including myopia, glaucoma, diabetic retinopathy, twin studies and relevant instruments and technologies.
Current projects include longitudinal studies on large cohorts which aim to investigate eye biomarker and phenotypes as predictors for important life events. The group has established the first Chinese High Myopia Registry consisting of over 1,000 individuals with high myopia. Long-term follow up studies aim to understand the natural history and risk factors for progression and the development of retinal damage. Another ongoing study is a twin registry of 9,000 pairs of young twins. Most of the twins were examined annually since 2006 and genome-wide scan has been completed for all samples now.
Prof. He's group is running a clinical trial on prophylaxis of angle closure in Chinese people where he enrolled 890 participants with angle closure and lasered one-randomly selected eye.
The group have also completed a clinical trial on the impact of outdoor intervention on the control of myopia, of which the significant findings have been reported in Journal of the American Medical Association (JAMA).
The group is also working on inventing devices that facilitate the diagnosis and surgery of eye disease
Dr Andreas Muller Deputy Director of WHO Collaborating Centre
Dr Fei Long Project Manager
Dr Jianbin Liu Research Assistant
Dr Sumit Parikh Research Assistant
Ms Kathy Fortis Research Assistant
Ms Liying Li Research Assistant
Dr William Yan M.D student
Prof Yizhi Liu, Zhongshan Ophthalmic Centre, Sun Yat-sen University
Prof Paul Foster, Institute of Ophthalmology, University College London
Prof David Mackey, Lions Eye Institute, University of Western Australia
Prof Tin Aung, Glaucoma Department, Singapore National Eye Centre
Prof Tien Wong, Vitreo-Retinal Department, Singapore National Eye Centre
Prof Ian Morgan, Research School of Biology, Australian National University
Prof David Friedman, Johns Hopkins Bloomberg School of Public Health and Wilmer Eye Institute, Johns Hopkins University
Prof Nathan Congdon, Queen's University Belfast, Belfast, UK
Dr Leon B. Ellwein, National Eye Institute, National Institutes of Health, United States
Assoc Prof Ying Chau, Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology
Assoc Prof Ching-Yu Cheng, Glaucoma Department , Singapore Eye Research Institute, Singapore
Development of an automated web-based screening system for eye diseases. BUPA Health Foundation, 2015-2018.
Key International Cooperative Research Project. National Natural Science Foundation, 2015-2019.
Scientific and Technological Innovation Leader. Ministry of Science and Technology, 2015-2017.
Intelligent Retinal Camera Project. Australian Cooperative Research Centre. 2013-2015.
Distinguished Young Scholar Award. National Natural Science Foundation, 2011-2015.
Development of preventive ophthalmology. State Key Laboratory Fund, State Science and Technology & Ministry of Education. 2009-2019.
Zhongshan Angle-closure Prevention Trial. Fight for Sight, UK 2008-2011.
Refractive error intervention program in China (ChildSight®). Michael Dell Susan Foundation. 2008-2010.
Guangzhou Twin Eye Study: Progression of myopia and genetic determinants. National Natural Scientific Committee 2007-2010.
Guangzhou Twin Eye Study. Sino-Australia Special Fund 2007-2008.
Prophylactic treatment and natural history of angle closure. Program for New Century Excellent Talents in University (NCET), Ministry of Education, 2007-2010.
Prophylactic treatment and natural history of angle closure. Project 5010, Sun Yat-sen University, 2006-2016.
Guangzhou Twin Eye Study. Department of Science and Technology, Guangzhou City Government. 2005-2008.
Prophylactic treatment of angle closure glaucoma. Department of Science and Technology, Guangdong Provincial Government 2005
Refractive Error Study in School-aged children in Guangzhou & Yangxi. World Health Organization, Geneva and National Eye Institute, USA N01-EY-9-2103. (2003-2004).
This research project is available to PhD students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
- Asia Pacific Research Accelerator (APRA) Program
- Development of an automated web-based screening system for eye diseases
- Web-based automated vision testing for cataract surgery outcome monitoring
- Guangzhou Twin Eye Study
- Asia Pacific Tele-Ophthalmology Society
- ZOC-BHVI High Myopia Cohort Study
Faculty Research Themes
School Research Themes
For further information about this research, please contact Professor Mingguang He