Cancer in Medicine

Cancer in all its forms, encompasses research, prevention, detection, treatment, care and health system transformation to address this most significant burden of disease.

Groups / Projects Research Lead Dept / Centre
A mouse model of duodenal atresia Project Leader Associate Professor Warrick Teague Paediatrics
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer Medicine
A5 SDHB Genomics Study Head of Laboratory Dr Richard Tothill Clinical Pathology
ACRF Translational Research Laboratory Group Leader Professor David S Ritchie
Medicine
Advanced Limb Reconstruction Head of Department of Surgery,
St. Vincent's Hospital,
Professor Peter Choong

Surgery
Brain Cancer Invasion Group Dr Stanley Stylli
Surgery
Brain Cancer Microenvironment and Biology Laboratory Dr Theo Mantamadiotis
Surgery
Brain Tumours and Epilepsy Associate Professor Andrew Morokoff
Surgery
Breast Cancer Head of Group Professor Bruce Mann
Lead Researcher Dr Anita Skandarajah
Surgery
Buchanan laboratory: Oncogenomics (colorectal cancer) Head of Laboratory Associate Professor Daniel Buchanan
Clinical Pathology
CANARY (CANcer risk in patients with unexpected weight loss in primaRY care) Studies: Clinical Decision Support Systems for Cancer Prevention and Early Cancer Detection in Primary Care Chief Investigator Dr. Javiera Martinez Gutierrez,

General Practice and Primary Care
Coin Laboratory: Cancer Bioinformatics Head of Laboratory Professor Lachlan Coin
Clinical Pathology
Cancer Biology Research Group Professor Graham Baldwin
Surgery
Cancer Immunotherapy symptoms: the experience and expectations around management Program Trial Coordinator Leeanne Pasanen Medicine
Cancer in Primary Care General Practice and Primary Care
Cancer Signaling Research Laboratory Dr Hong-Jian Zhu
Surgery
Care Plus Study Research Assistant Roslyn Le Gautier Medicine
Centre for research excellence in cervical cancer control Obstetrics, Gynaecology and Newborn Health
Characterisation of complex structural variation in bacterial and human genomes Group Lead, Cancer Bioinformatics Professor Lachlan Coin Clinical Pathology
Circulating Biomarkers in Liver Malignancy Professor Christopher Christophi Surgery
Developing clinical genomic methods for cancer of unknown primary Head of Laboratory Dr Richard Tothill Clinical Pathology
Elizabeth Vincan Professor Elizabeth Vincan
Infectious Diseases
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit Research Group Leader A/Prof Michelle Peate
Obstetrics, Gynaecology and Newborn Health
Endocrine Surgery Associate Professor Julie Miller
Surgery
Enhance: A multi-centre, randomised phase IV study Medicine
Establishing patterns of primary health care usage in cancer at the end of life Matthew Grant Medicine
Evaluating molecular biomarkers of anal cancer risk Obstetrics, Gynaecology and Newborn Health
Fertility After Cancer Predictor (FoRECAsT) Study Project Lead A/Prof Michelle Peate Obstetrics, Gynaecology and Newborn Health
Fertility preservation in children and teenagers with cancer Senior Lecturer Dr Yasmin Jayasinghe Obstetrics, Gynaecology and Newborn Health
Future Health Today: A randomised control trial of pharmacological therapies to reduce cardiovascular risk in people with chronic kidney disease and investigation of people at increased risk of cancer Study Coordinator Ms. Sophia Chima,

General Practice and Primary Care
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA Group Lead, Cancer Bioinformatics Professor Lachlan Coin Clinical Pathology
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers Group Lead, Cancer Bioinformatics Professor Lachlan Coin Clinical Pathology
Glioblastoma Survival Signaling Lab Dr Rodney Luwor
Surgery
Gynaecology Research Centre - Hickey Group Research Group Leader Professor Martha Hickey
Obstetrics, Gynaecology and Newborn Health
Head and Neck Tumour Stream Research Group Professor David Wiesenfeld
Surgery
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer Head of Laboratory Professor Fred Hollande
Clinical Pathology
Honorary Appointments’ Research Projects Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance Professor Christopher Christophi Surgery
How many women experience long-term side-effects after cancer and cancer treatment? Project Lead A/Prof Michelle Peate Obstetrics, Gynaecology and Newborn Health
Human Liver Organoids Project Lead Professor Kumar Visvanathan Medicine
IC3 Trial: A Randomised Control Trial aiming to improve early diagnosis of liver cancer and improving patient health outcomes IC3 National Manager Dr. Deborah De Guingand,

General Practice and Primary Care
Identifying and characterising Lynch syndrome within the population Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying biomarkers of risk and poor prognosis in CRC Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Improving reproductive health through infectious diseases research Obstetrics, Gynaecology and Newborn Health
Informal Communities in Cancer Treatment Project Lead Dr Matt Grant Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia Professor David S Ritchie Medicine
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer Group Leader, acting Head of Department Associate Professor Fred Hollande Clinical Pathology
Liver Group Professor Christopher Christophi
Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer Project Lead A/Prof Michelle Peate Obstetrics, Gynaecology and Newborn Health
MAGPIE Study: A genomic test intervention designed to provide patients with personalised melanoma, bowel, breast, and prostate cancer screening information Study Coordinator Dr. Sibel Saya,

General Practice and Primary Care
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation Project Lead Dr Rachel Koldej Medicine
Manometric studies on oesophageal atresia and colorectal disorders Project Leader Dr Sebastian King Paediatrics
Molecular Mechanisms of Tumour Resistance Laboratory Dr Rodney Luwor Surgery
Molecular Microbiology and Reproductive Health Research Group Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland
Obstetrics, Gynaecology and Newborn Health
Neurosurgery Professor Kate Drummond
Surgery
Novel investigations and treatments for intractable, chronic constipation Project Leader Dr Bridget Southwell Paediatrics
Novel treatments for colorectal disorders Project Leader Dr Sebastian King Paediatrics
OPPtiC: A pilot feasibility study of establishing a clinical opioid pharmacogenomics database in palliative care Program Trial Coordinator Leeanne Pasanen Medicine
Optimising the management of patients awaiting liver transplantation Professor Christopher Christophi
Senior Lecturer Michael Fink
Surgery
PaCCSC RAPID Series - Cancer-related Lymphoedema Beth Russell Medicine
Paediatric and Adolescent Fertility Preservation Taskforce A/Prof Yasmin Jayasinghe
Obstetrics, Gynaecology and Newborn Health
Paediatric Fertility Decision Aid Study Project Lead A/Prof Michelle Peate Obstetrics, Gynaecology and Newborn Health
Jennifer Philip Group Leader Professor Jennifer Philip
Medicine
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility Project Leader Dr Ruili Li Paediatrics
PRESIDE Trial: A Randomised Controlled Trial providing antidepressant medication information to patients with mild-to-severe depressive symptoms. Trial Coordinator Dr Sibel Saya,

General Practice and Primary Care
Priorities and Needs of Women Living with Advanced Cancer Project Lead Dr Michelle Peate Obstetrics, Gynaecology and Newborn Health
Probiotic therapy Obstetrics, Gynaecology and Newborn Health
Promoting and advancing midlife health in women Project Leader Professor Martha Hickey Obstetrics, Gynaecology and Newborn Health
Prostate Cancer Head of Group Professor Christopher Hovens
Deputy Laboratory Head Associate Professor Niall Corcoran
Surgery
Prostate Cancer Research Group Professor Christopher Hovens
Surgery
RAPID Postmarketing Study - Medicinal Cannabis Medicine
Rare Disease Oncogenomics Head of Laboratory Associate Professor Richard Tothill
Clinical Pathology
Recipient immunity as a determinant of long term outcome in bone marrow transplantation Group Leader Professor David Ritchie Medicine
Regulation of cancer stem cell self-renewal in colorectal cancer Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion Dr Stanley Stylli Surgery
Renal supportive care of patients with advanced chronic kidney disease Kathryn Ducharlet Medicine
Reproductive Steroids Research Group Professor Mathis Grossmann, MD, PhD, FRACP
Medicine
The role of the essential biometal zinc in pathological and physiological processes Professor Graham Baldwin
Dr Oneel Patel
Dr Joseph Ischia
Surgery
Role of p-21-activated kinases in pancreactic cancer Professor Graham Baldwin
Dr Mehrdad Nikfarjam
Surgery
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection Professor Christopher Christophi Surgery
SCRIPT Trial: A Randomised Controlled Trial utilising a genomic test as an intervention providing personalised bowel cancer screening information Trial Coordinator Dr. Sibel Saya,

General Practice and Primary Care
Serum biomarkers of brain cancer Dr Andrew Morokoff Surgery
SMARTERScreen: A Randomised Controlled Trial based on evidence from SMARTScreen utilising SMS messages to prompt patients overdue with bowel cancer screening Trial Coordinator Ms Anna Wood,

General Practice and Primary Care
Spinal Biology Laboratory Doctor Gerald Quan
Surgery
STEP Care Clinical Trial Project Lead Anna Collins Medicine
Surgical Research Group Chair of Paediatric Surgery Professor John M Hutson AO
Paediatrics
T cell function as a determinant of blinatumomab efficacy in B-ALL Group Leader Professor David Ritchie Medicine
Targeting the angiogenic and osteoclastic pathways in spinal cancer Doctor Gerald Quan
Doctor Gerald Quan
Surgery
Targeting the Lymphatics in colorectal Liver metastasis Professor Christopher Christophi Surgery
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production Professor Michael McCullough Surgery
The role of invadopodia in glioma invasion and response to therapeutics Dr Stanley Stylli Surgery
The role of miRNA in oral mucosal disorders Professor Michael McCullough Surgery
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies Professor David S Ritchie Medicine
Understanding the aetiology of Serrated Polyposis Syndrome Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma Surgeon, Project Leader Dr David Gyorki Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism Project Leader Professor John M Hutson AO Paediatrics
Use of Connexin43 peptides as a treatment for glioma Dr Stanley Stylli Surgery
VCCC Building Capability in Clinical Trials Program Program Trial Coordinator Leeanne Pasanen Medicine
Western Health Cancer Research Group Leader Dr Dishan Herath
Medicine
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study. Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey Obstetrics, Gynaecology and Newborn Health

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