Psychiatric Neuropathology Laboratory

Psychiatric Neuropathology Laboratory

THE LABORATORY

The laboratory is engaged in research to elucidate the changes in brain chemistry associated with psychiatric disorders. A better understanding of the chemical imbalances that occur with disorders such as schizophrenia, bipolar disorder and major depressive disorder will be the foundation for the design of more effective targeted therapies for people with the disorder.

The laboratory, which is partly based at the Royal Melbourne Hospital, is currently staffed by neuroscientists with a particular interest in the biochemistry of psychiatric disorders. The group undertakes research, predominantly using brain, blood and other tissue samples, as well as a variety of other approaches including cell culture and animal studies, to identify changes in the brain chemistry of people. In addition to finding changes in the brain chemistry, the group tries to determine the causes and consequences of these changes to create a biochemical snapshot of what is happening in the brains of people with psychiatric disorders.

In addition to the leadership of Professor Everall, the Laboratory has continued its highly productive collaboration with Professor Stan Skafidas, Director of the Centre for Neural Engineering who is also an Honorary Member of the Department of Psychiatry and Professor Christos Pantelis, Scientific Director, Melbourne Neuropsychiatry Centre, Department of Psychiatry on molecular changes in developmental disorders such as autism spectrum disorder as well as major psychiatric disorders such as schizophrenia.