CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer

Project Details

Lung cancer is the most common cancer worldwide, with 1.3 million new cases diagnosed every year. It has one of the lowest survival outcomes of any cancer because over two-thirds of patients are diagnosed when curative treatment is not possible. This trial is a phase II, multisite, randomised controlled trial, for patients at increased risk of lung cancer in the primary care setting, to facilitate early presentation with symptoms of lung cancer. The intervention is based on a previous Scottish CHEST Trial that comprised of a primary-care nurse consultation to discuss and implement a self-help manual, followed by self-monitoring reminders to improve symptom appraisal and encourage help-seeking in patients at increased risk of lung cancer.


Emily Habgood, Research Assistant
Sonya Murray, PhD Candidate, UWA
Yvonne Kutzer, Research Assistant, UWA


Peter Murchie, The Centre of Academic Primary Care, The University of Aberdeen, Aberdeen, UK
Fiona Walter, The Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
Danielle Mazza, Department of General Practice, Monash University, Melbourne, Victoria, Australia
Andrew Martin, NHMRC Clinical Trials Centre, University of Sydney, New South Wales, Australia
Stephen Goodall, Centre for Health Economics Research and Evaluation (CHERE), University of Technology, Sydney, New South Wales, Australia
David Barnes, Royal Prince Alfred Hospital and Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia


This trial is funded by the National Health and Medical Research Council (NHMRC).

Research Outcomes

Murray SR, Kutzer Y, Habgood E, Murchie P, Walter FM, Mazza D, Shahid S, Emery JD. Reducing barriers to consulting a General Practitioner in patients at increased risk of lung cancer: a qualitative evaluation of the CHEST Australia intervention, Family Practice, cmx057,

Murray SR, Murchie P, Campbell N, Walter FM, Mazza D, Habgood E, Kutzer Y, Martin A, Goodall S, Barnes DJ, Emery JD. Protocol for the CHEST Australia Trial: a phase II randomised controlled trial of an intervention to reduce time-to-consult with symptoms of lung cancer. BMJ open 2015; 5(5): e008046.

Research Group

Cancer in Primary Care

Faculty Research Themes


School Research Themes

Cancer in Medicine

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

General Practice

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