Diabetes Technology Research Group

Research Overview

Professor David O’Neal leads his own research group based at the University Of Melbourne, Department Of Medicine at St Vincent’s Hospital. He has led studies with significant national and international collaborations involving clinicians, academics and industry. In addition to planning his own investigator- initiated studies he has provided input into study design of commercially sponsored studies which his team has conducted.

The D.T.R.G Mission is to improve the lives of people with diabetes through exceptional research that drives advancement in innovative technologies.

Their vision is to be the centre of excellence in Adult t1 diabetes technology research in Australia and the leading partner for collaborators, participants, industry and key stakeholders.


Professor David O’Neal, Head of DTRG Principal  Investigator
Professor Alicia Jenkins, Principal Investigator
Catriona Sims, Project Portfolio Manager
Dr Melissa Lee, Clinical Physician (PHD)
Dr Barbora Paldus, Clinical Physician (PHD)
Dr  Balasubramanian Krishna Murthy, Clinical Physician
Dr Nisha Venkatesh, Research Fellow
Varuni Obeyesekere, Scientist
Sue Kent, Registered Nurse 
Katie Brown, Clinical Research Co-ordinator
Dr Dale Morrison, Clinical Research Co-ordinator, Exercise Physiologist
Lesley Robinson, Clinical Research Co-ordinator, Credentialed Diabetes Educator
Emma Netzer, Clinical Research Co-ordinator, Credentialed Diabetes Educator
Hannah Jones, Clinical Research Co-ordinator, Credentialed Diabetes Educator



Juvenile Diabetes Research Foundation International
Juvenile Diabetes Research Foundation Australia
Helmsley Charitable Trust
St Vincent's Hospital Melbourne Research Endowment Fund

Research Opportunities

This research project is available to PhD, Honours to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Publications

Zaharieva, D., Messer, M., Paldus, B., O’Neal, D., Maahs, D., Riddell, M. (2020). Physical activity and exercise using closed loop technology.  Accepted for publication Canadian Journal of Diabetes

Venkatesh, N., Paldus, B., Lee, MH., MacIsaac, RJ., Jenkins, AJ., O’Neal, DN. (2020). COVID-19, Type 1 Diabetes Clinical Practice, Research and Remote Medical Care: A View From the Land Down-Under. Accepted for publication Journal of Diabetes Science and Technology

Zaharieva D, Teng JH, Ong ML, Lee MH, Paldus B, Jackson L, Holihan CA, Shub A,Tipnis S, Cohen O, O'Neal DN, Krishnamurthy B. (2020). CONTINUOUS GLUCOSE MONITORING VERSUS SELF-MONITORING OF BLOOD GLUCOSE TO ASSESS GLYCEMIA IN GESTATIONAL DIABETES. Diabetes Technol Ther. 2020 Apr 23.

Paldus, B., Lee, MH., Jones, HM., Et Al. (2019). Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study. Diabetes Technol Ther. 21(1):56-58.

Paldus, B., Zaharieva, D. (2019). D-I-Y Pancreas. Diabetes Management Journal May 2019

Lee, MH., Vogrin, S., Paldus, B., Et Al. (2019). Glucose and Counterregulatory Responses to Exercise in Adults with Type 1 Diabetes and Impaired Awareness of Hypoglycemia Using Closed-Loop Insulin Delivery: A Randomized Crossover Study. Diabetes Care. 43. dc191433. 10.2337/dc19-1433

Lee, MH., Vogrin, S., Paldus, B., Et Al. (2019). Glucose Control in Adults with Type 1 Diabetes Using Medtronic Prototype Enhanced-Hybrid Closed-Loop System: A Feasibility Study. Diabetes Technol Ther. 21(9):499-506. doi:10.1089/dia.2019.0120

Lee, MH., Paldus, B., Krishnamurthy, B., et al. (2019). The Clinical Case for the Integration of a Ketone Sensor as Part of a Closed Loop Insulin Pump System. J Diabetes Sci Technol. January:1932296818822986. doi:10.1177/1932296818822986

Paldus, B., Lee, MH., O’Neal, DN. (2018). Insulin Pumps in General Practice. Australian Prescriber. 41. 186-190. 10.18773/austprescr.2018.056.

McAuley SA, de Bock MI, Sundararajan V, Lee MH, Paldus B, Ambler GR, Bach LA, Burt MG, Cameron FJ, Clarke PM, Cohen ND, Colman PG, Davis EA, Fairchild JM, Hendrieckx C, Holmes-Walker DJ, Horsburgh JC, Jenkins AJ, Kaye J, Keech AC, King BR, Kumareswaran K, MacIsaac RJ, McCallum RW, Nicholas JA, Sims C, Speight J, Stranks SN, Trawley S, Ward GM, Vogrin S, Jones TW, O'Neal DN. (2018). Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: A randomised controlled trial protocol. BMJ open. 8. e020274. 10.1136/bmjopen-2017-020274

Lee, MH., Paldus, B., O’Neal, DN. (2017). Type 1 diabetes and the Artificial Pancreas.  Diabetes Management Journal

Morrison, D., et al. (2020) Kinetics of Continuously Measured Interstitial Versus Venous Lactate Following High Intensity Exercise in Adults With Type 1 Diabetes. Diabetes Technology & Therapeutics. Vol. 22. 140

Research Projects

School Research Themes


Key Contact

For further information about this research, please contact Group Leader Professor David O'Neal

Department / Centre

Medicine and Radiology , St Vincent's Hospital

Unit / Centre

Diabetes Technology Research Group

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