Diabetes Technology Research Group

Research Overview

Professor David O’Neal leads his own research group based at the University Of Melbourne, Department Of Medicine at St Vincent’s Hospital. He has led studies with significant national and international collaborations involving clinicians, academics and industry. In addition to planning his own investigator- initiated studies he has provided input into study design of commercially sponsored studies which his team has conducted.

The DTRG Mission is to improve the lives of people with diabetes through exceptional research that drives advancement in innovative technologies. Their vision is to be the centre of excellence in Adult Type 1 diabetes technology research in Australia and the leading partner for collaborators, participants, industry and key stakeholders.

Our group received the University of Melbourne 2020 MDHS Award for Excellence in Team-Based Research Programs for working nationally and internationally with and for people living with Type 1 diabetes to improve their health outcomes.

Further information about our research can be found on the DTRG website


Professor David O’Neal, Head of DTRG Principal  Investigator
Professor Alicia Jenkins, Principal Investigator
Catriona Sims, Project Portfolio Manager
Dr Melissa Lee, Clinical Physician (PHD)
Dr Barbora Paldus, Clinical Physician (PHD)
Dr  Balasubramanian Krishna Murthy, Clinical Physician
Dr Nisha Venkatesh, Research Fellow
Varuni Obeyesekere, Scientist
Sue Kent, Registered Nurse 
Katie Brown, Clinical Research Co-ordinator
Dr Dale Morrison, Clinical Research Co-ordinator, Exercise Physiologist
Lesley Robinson, Clinical Research Co-ordinator, Credentialed Diabetes Educator
Emma Netzer, Clinical Research Co-ordinator, Credentialed Diabetes Educator
Hannah Jones, Clinical Research Co-ordinator, Credentialed Diabetes Educator



Juvenile Diabetes Research Foundation International
Juvenile Diabetes Research Foundation Australia
Helmsley Charitable Trust
St Vincent's Hospital Melbourne Research Endowment Fund

Research Publications

Zaharieva DP, Messer LH, Paldus B, O’Neal DN, Maahs DM and Riddell MC (2020), Glucose control during physical activity and exercise using closed loop technology in type 1 diabetes, Canadian Journal of Diabetes

Venkatesh N, Paldus B, et al. (2020) COVID-19, Type 1 Diabetes Clinical Practice, Research, and Remote Medical Care: A View From the Land Down-Under., Journal of Diabetes Science and Technology, vol 14, no 4, pp 803-804

Morrison D, et al, (2020), Kinetics of Continuously Measured Interstitial Versus Venous Lactate Following High Intensity Exercise in Adults With Type 1 Diabetes, Diabetes Technology & Therapeutics,  Vol. 22. 140

Zaharieva D, Teng JH, Ong ML, Lee MH, Paldus B, Jackson L, Holihan CA, Shub A, Tipnis S, Cohen O, O'Neal DN, Krishnamurthy B, (2020), Continuining glucose monitoring versus self-monitoring of blood glucose to assess glycemia in gestational diabetes, Diabetes Technol Ther, Apr 23

Paldus B, Lee MH, Jones HM, et Al, (2019), Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study, Diabetes Technol Ther. 21(1):56-58

Paldus B, Zaharieva D, (2019), D-I-Y Pancreas, Diabetes Management Journal May 2019

Lee MH, Vogrin S, Paldus B, et al, (2019), Glucose and Counterregulatory Responses to Exercise in Adults with Type 1 Diabetes and Impaired Awareness of Hypoglycemia Using Closed-Loop Insulin Delivery: A Randomized Crossover Study, Diabetes Care, 43. dc191433. 10.2337/dc19-1433

Lee MH, Vogrin S, Paldus B, et al, (2019), Glucose Control in Adults with Type 1 Diabetes Using Medtronic Prototype Enhanced-Hybrid Closed-Loop System: A Feasibility Study, Diabetes Technol Ther, 21(9):499-506. doi:10.1089/dia.2019.0120

Lee MH, Paldus B, Krishnamurthy B, et al, (2019), The Clinical Case for the Integration of a Ketone Sensor as Part of a Closed Loop Insulin Pump System, J Diabetes Sci Technol. January: 1932296818822986. doi:10.1177/1932296818822986

Paldus B, Lee MH, O’Neal DN, (2018), Insulin Pumps in General Practice, Australian Prescriber, 41. 186-190. 10.18773/austprescr.2018.056.

McAuley SA, de Bock MI, Sundararajan V, Lee MH, Paldus B, Ambler GR, Bach LA, Burt MG, Cameron FJ, Clarke PM, Cohen ND, Colman PG, Davis EA, Fairchild JM, Hendrieckx C, Holmes-Walker DJ, Horsburgh JC, Jenkins AJ, Kaye J, Keech AC, King BR, Kumareswaran K, MacIsaac RJ, McCallum RW, Nicholas JA, Sims C, Speight J, Stranks SN, Trawley S, Ward GM, Vogrin S, Jones TW, O'Neal DN, (2018), Effect of 6 months of hybrid closed-loop insulin delivery in adults with type 1 diabetes: A randomised controlled trial protocol, BMJ open, 8. e020274. 10.1136/bmjopen-2017-020274

Lee MH, Paldus B, O’Neal DN, (2017), Type 1 diabetes and the Artificial Pancreas, Diabetes Management Journal

Research Projects

School Research Themes


Key Contact

For further information about this research, please contact Group Leader Professor David O'Neal

Department / Centre


Unit / Centre

Diabetes Technology Research Group

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