Enhance: A multi-centre, randomised phase IV study

Project Details

Introduction: This collaborative study compares newer formulations of oxycodone across different settings for people with cancer

Title - Enhance: A multi-centre, randomised, phase IV study to compare the efficacy of oxycodone/naloxone verses oxycodone prolonged release tablets in patients with advanced cancer

Key Aim To evaluate two pain relief medications, oxycodone/naloxone prolonged-release (OXN PR) and oxycodone alone prolonged-release (Oxy PR) with respect to analgesic efficacy and constipation in patients with advanced cancer.

Further Information: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377673&isReview=true


Principal Investigator: Dr Aaron Wong, Peter MacCallum Cancer Centre (Aaron.wong@petermac.org)





Research Group

Palliative Nexus

Faculty Research Themes


School Research Themes

Cancer in Medicine

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Medicine and Radiology


St Vincent's Hospital

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