Depression and Anxiety Neuroscience
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Ben Harrison+613 8344 1959
Research Overview
Our research group is devoted to the neuroscience of cognitive and affective processes and their role in mood and anxiety disorders – the most common form of mental illness.
We conduct experimental functional brain imaging research in healthy and clinical populations targeting core psychological domains of interest (e.g., self-related cognition, emotion/affect regulation, interoception). Clinically, we seek to develop treatment-oriented imaging biomarkers, and have sucessfully integrated our work into large-scale clinical trials.
Staff
- Prof Chris Davey, Head of Department
- Dr Trevor Steward, NHMRC post-doctoral fellow
- Lisa Incerti, Project co-ordinator
- Rachel Brodie, Research assistant
- Micah Cearns, Research assistant
- Laura Finlayson-Short, PhD student
- Hannah Savage, PhD student
- Alec Jamieson, PhD student
- Patrick Laing, PhD student
- Christine Leonards, PhD student
- Rebekah Truman, Honours student
Funding
PI Harrison, NHMRC project grant: "A neural systems model of fear dysregulation in anxiety disorders"
PI Harrison, NHMRC project grant: "A brain-based model of anxiety senstivity in panic disorder"
PI Davey, NHMRC project grant: "A randomised controlled trial of low-dose ketamine in youth with severe depression and elevated suicide risk".
PI Harrison, NHMRC fellowship: "Depression and anxiety neuroscience"
Research Publications
TOP 5 publications
Savage H, Davey CG, Fullana MA, Harrison BJ (2020). Clarifying the neural substrates of threat and safety reversal learning in humans. NeuroImage 207: 116427. PubMed
Harrison BJ, Fullana MA, Via E, et al. (2017). Human ventromedial prefrontal cortex and the positive affective processing of safety signals. Neuroimage 152:12–18. PubMed
Davey CG, Breakspear M, Pujol J, Harrison BJ (2017) A brain model of disturbed self-appraisal in depression. American Journal of Psychiatry 174(9):895–903. PubMed
Davey CG, Pujol J, Harrison BJ (2016) Mapping the self in the brain’s default mode network. Neuroimage 132:390–397. PubMed
Fullana MA, Harrison BJ, Soriano-Mas C, et al. (2016) Neural signatures of human fear conditioning: an updated and extended meta-analysis of fMRI studies. Molecular Psychiatry 21(4):500–508. PubMed
Research Projects
For project inquiries, contact our research group head.
Faculty Research Themes
School Research Themes
Key Contact
For further information about this research, please contact Professor of Cognitive and Clinical Neuroscience Ben Harrison
Department / Centre
Psychiatry , Melbourne Neuropsychiatry Centre
MDHS Research library
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