Depression and Anxiety Neuroscience

Project Details

Our aim is to develop experimental models based on affective neuroscience for treatment-oriented research and discovery in mood and anxiety disorders.


Large-scale brain functional systems; emotion, affect and self-related processes; brain-body interactions.
Please contact us to discuss specific projects.


Functional magnetic resonance imaging (fMRI); psychophysiological monitoring, experimental cognitive and affective neuroscience.


Ben Harrison
Chris Davey (Orygen)
Lianne Schmaal (Orygen)
Lisa Incerti
Katerina Stephanou
Laura Finlayson-Short
Kirra Liu
Sally Cansdale
Hannah Savage


  • NHMRC 1025619; 1064643; 1124472


Ben Harrison
Office 345,
Level 3, 161 Barry Street,
Carlton, Melbourne, Australia
Phone: (+613) 8344-1959

Research Publications

  1. Davey CG, Pujol J, Breakspear M, Harrison BJ. A brain model of disturbed self appraisal in depression. The American Journal of Psychiatry (2017)
  2. Harrison BJ, et al. Human ventromedial prefrontal cortex and the positive affective processing of safety signals. NeuroImage. (2017)
  3. Fullana MA, Harrison BJ, et al. Neural signatures of human fear conditioning: an updated and extended meta-analysis of fMRI studies. Molecular Psychiatry (2016)
  4. Schmaal et al. Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry (2016)
  5. Davey CG, Pujol J, Harrison BJ. Mapping the self in the brain’s default mode network. NeuroImage (2016)
  6. Stephanou K, Davey CG, Kerestes R, Whittle W, Pujol J, Yucel M, Fornito A, Lopez-Sola M, Harrison BJ. “Brain functional correlates of emotion regulation across adolescence and young adulthood”. Human Brain Mapping (2016)
  7. Harrison et al. “A neural mediator of human anxiety sensitivity”. Human Brain Mapping (2015)

Research Group

Melbourne Neuropsychiatry Centre Research

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre


MDHS Research library
Explore by researcher, school, project or topic.