Survey of High Impact Psychosis (SHIP)

• 
  Director, Psychosocial Research Centre
  Professor Carol Harvey

  c.harvey@unimelb.edu.au

  +61 3 9355 9825

Project Details

An empirical framework for assessing mortality and morbidity in people with psychotic disorders: A 7-year prospective and 10-year prospective follow-up of 2075 participants in the Survey of High Impact Psychosis (SHIP) using linked Registers.

1. It is well established that physical morbidity and premature mortality are elevated in schizophrenia.  The investigators who collaborated on the 2010 National Survey of High Impact Psychosis (SHIP), have cross-sectional data revealing rates of physical morbidity among SHIP participants well above population rates and exposing a very high cost burden.  However there is a critical need for longitudinal data.  This NHMRC project grant builds on a unique opportunity to use an innovative dual-methods strategy.  17 years (2000-2017) of mortality and physical morbidity outcome data from state and national registers have been extracted.  These register data are being combined with previously-collected survey data for a large, nationally representative and comprehensively characterised sample of 2075 people aged 18-64 years with psychotic disorders who took part in SHIP.  The aims are to: Estimate rates of 7-year mortality and morbidity in people with a psychotic disorderliness with separate estimates for: (i) mortality due to natural versus unnatural causes; and (ii) potentially avoidable morbidity in order to establish much needed Australian benchmarks for assessing the impact of changes in public health policies.
2. Examine the impact of sets of risk factors on 7-year mortality and morbidity in order to move beyond estimation of rates to understanding the aetiology of adverse physical health outcomes in psychotic disorders and informing clinical practice.
3. Develop and validate predictive risk equations for cardiovascular disease (CVD) for use with people with psychotic disorders in order to address a clinical need for CVD predictive risk equations appropriate for use in this subpopulation.
4. Calculate the economic burden of severe and acute physical morbidity in addition to mental health impacts in order to meet a service planning need for scarce and accurate data on costs of physical morbidity in psychotic disorders.

Researchers

Professor Carol Harvey
Prof  Ellie Fossey
Catherine Bressanutti
Dr Christine Migliorini
Lenice Murray
Alicia King
Samantha Zuccarelli

Collaborators

La Trobe University
University of Western Australia
University of Adelaide
University of New South Wales
University of Newcastle
University of Queensland
University of Tasmania
Hunter New England Local Health District
Mind Australia
Orygen Research Centre
St Vincents Hospital, Melbourne

Funding

• Commonwealth Department of Health and Aging - two year
• La Trobe University Faculty of Health Sciences Faculty Research Funding-twelve months
• NHMRC project - five years

Research Outcomes

Harvey C, Brophy L, Parsons S, Moeller-Saxone K, Grigg M and Siskind D. People living with psychosocial disability: Rehabilitation and recovery-informed service provision within the second Australian national survey of psychosis. Early online in Australian and New Zealand Journal of Psychiatry.

Haydock M, Cowlishaw S, Harvey C and Castle D. Prevalence and correlates of problem gambling in people with psychotic disorders. Comprehensive Psychiatry 2015; 58: 122-129.

Shah S, Mackinnon A, Galletly C, Carr V, McGrath J, Stain H, Castle D, Harvey C, Sweeney S and Morgan V. Prevalence and impact of childhood abuse in people with a psychotic illness. Data from the second Australian national survey of psychosis. Schizophrenia Research 2014; 159: 20-26.

Morgan V, McGrath J, Jablensky A, Badcock J, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, Hocking B, McGorry P, Neil A, Saw S, Shah S, Stain H and Mackinnon A.  Psychosis prevalence and physical, metabolic and cognitive comorbidity. Data from the second Australian national survey of psychosis. Psychological Medicine 2014; 44: 2163-2176.

Morgan V, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S & Saw S.  People living with psychotic illness in 2010. The second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry 2012; 46: 735–752.

Harvey C, Killackey E, Groves A & Herrman H. A place to live: housing needs for people with psychotic disorders identified in the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry 2012; 46: 840 – 850.

Stain H, Galletly C, Clark S, Wilson J, Killen E, Anthes L, Campbell L, Hanlon M-C & Harvey C.  Understanding the social costs of psychosis: The experience of adults affected by psychosis identified within the second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry 2012; 46: 879–889.

Waghorn G, Saha S, Harvey C, Morgan V, Waterreus A, Bush R, Castle D, Galletly C, Stain H, Neil A, McGorry P & McGrath J. “Earning and learning” in those with psychotic disorders: the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry 2012; 46: 774–785.