Departmental Seminars

Every week on Monday, until 9 Dec 2019
-

2019 Seminars Series

(no RSVP required)

Light lunch served from 12.20pm

Forthcoming seminars:

Characterising the impacts of cancer therapies on the female reproductive tract
Monday 21 October 2019 - 12.30pm - Level 7, RWH Hospital Seminar Room 7A/B
Amy Winship, Monash University

Attention has shifted from conventional cancer therapies to more targeted treatments with reduced off-target effects. PARP inhibitors and immunotherapies have entered the clinic, with no preclinical investigations of impacts to fertility. The number and quality of primordial follicle oocytes in the ovary are non-renewable and essential for fertility. We’ve shown the PARP inhibitor, olaparib, depletes primordial follicles in mice. We are examining impacts of immunotherapies on the ovaries in mice. And importantly, while the oncofertility filed has largely focused on the ovary, we aim to uncover the impacts of radiotherapy and chemotherapy on the uterus in vivo.


NO WEEKLY GOSS THIS WEEK
Monday 28 October 2019


NO WEEKLY GOSS DUE TO MELBOURNE CUP DAY
Monday 4 November 2019


Mass Spectrometry Imaging to identify the metabolities within endometriosis tissue
Monday 11 November 2019 - 12.30pm - Level 7, RWH Hospital Seminar Room 7D/E
Brayden Fraser, Student (MSc Biosciences), University of Melbourne

The aim of this project was to develop our understanding of the site-specific metabolites associated with endometriotic lesion foci in comparison to myometrium and endometrium tissue. This study accessed archival FFPE tissues and MSI to enable the direct spatial examination of metabolites specific to ectopic endometrial foci, eutopic endometrium and myometrium. Notable identified species included stearic and palmitic acid, found in a higher intensity within diseased tissues compared to non-diseased tissues. This investigation demonstrates the potential of accessing FFPE pathology specimens for metabolomics-based MSI to advance our understanding of endometriotic lesion activity.


NO WEEKLY GOSS DUE TO RESEARCH WEEK
Monday 18 November 2019


Presentation
Monday 25 November 2019 - 12.30pm - Level 7, RWH Hospital Seminar Room 7D/E
Stefan Kane, Royal Women's Hospital


Monday 2 December 2019 - 12.30pm - Level 7, RWH Hospital Seminar Room 7A/B
Jennifer Marino
University of Melbourne


Monday 9 December 2019 - 12.30pm - Level 7, RWH Hospital Seminar Room 7A/B
Ruth Escalona
PhD Presentation


Any queries regarding this seminar, please contact Kathryn Ryan ryan.k@unimelb.edu.au