CITE is a research group within the Academic Unit for Psychiatry of Old Age in the Department of Psychiatry, co-led by Dr Amit Lampit and Dr Alex Bahar-Fuchs. We develop, evaluate, implement and study the mechanisms of cognition-oriented treatments across the lifespan and brain disorders.
Some specific questions underlying our group’s research include:
- How can cognitive treatments best support cognition and function in healthy people and those with cognitive impairments?
- What are the biopsychosocial mechanisms that underpin cognitive treatment gains?
- How can emerging technologies be used to optimise the benefits of cognitive treatments?
- How to effectively combine cognitive and other evidence-based treatments (e.g., physical exercise and behaviour change) for best outcomes?
- What are the most appropriate trial methodologies to advance research on cognitive interventions?
- How can evidence synthesis methods be used to answer key clinical questions regarding the effects of cognitive treatments?
Projects conducted in our lab are multidisciplinary and involve a range of methodologies. We have extensive collaborations with researchers in Melbourne, as well as nationally and internationally. Our projects tend to fall into three broad research themes:
- Optimising intervention design (including with emerging technologies)
- Optimising trial design, implementation, and reporting
- Optimising evidence synthesis methods
Dr Amit Lampit - Research Fellow and group co-head
Dr Alex Bahar-Fuchs - Senior Research Fellow and group co-head
Dr Anna Wolf - Postdoctoral Research Fellow
Ms Julieta Sabates - (research assistant)
Dr Harry Hallock - Postdoctoral Research Fellow (Charité)
Ms Mary Castellani - PhD Candidate (La Trobe)
Ms Hanna Malmberg-Gavelin - PhD Candidate (University of Umeå)
Simultaneous Physical and Cognitive Exercise (SPACE): Our in-house technology for delivering concurrent cognitive and physical training in older adults and people with cognitive impairments
VR-based cognitive training: Using virtual reality to enhance the effectiveness and user experience of cognitive training, especially for older adults with mild cognitive impairment and dementia
Indoor spatial tracking for continuous, unobtrusive and objective functional assessment in in older adults
Anstey K, Bahar-Fuchs A, Sargent-Cox K. (2014). Longitudinal studies in clinical geropsychology. In Pachana NA & Laidlaw K (Eds). The Oxford Handbook of Clinical Geropsychology: International Perspectives (pp. 20-61). UK: Oxford University Press [Abstract]
Lampit A, Duffy S, Valenzuela M. (2016). Translating physical activity into a therapy for the mind: How does it work? In LC Lam & M Riba (Eds.), Physical Exercise Interventions for Mental Health (pp. 147-163). Cambridge, UK: Cambridge University Press [Abstract]
|Commentaries and Editorials|
Lampit A, Valenzuela M. (2015). Pointing the FINGER at multimodal dementia prevention. The Lancet 386, 1625-6 [Full text]
Lampit A, Valenzuela M, Gates N. (2015). Computerized cognitive training is beneficial for older adults. Journal of the American Geriatrics Society 63:2610-2 [PubMed]
Lampit A, Valenzuela M, Gates N. (2015). Response to Dr. Edward Ratner et al. Journal of the American Geriatrics Society 63:2615 [PubMed]
Mabulal GM, Quiroz YT, Albensi BC, Arezana-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, et al. (In press). Perspectives on Ethnic and Racial Disparities in Alzheimer’s Disease and Related Dementias: Update and Areas of Immediate Need. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association.
Heffernan M, Andrews G, Fiatarone Singh M, Valenzuela M, Anstey K, Maeder A, McNeil J, Jorm L, Lautenschlager N, Sachdev P, Chau T, Ginige A, Hobbs M, Walton C, Lampit A, Kochan N, Mavros Y, Noble Y, Maintain Your Brain Collaborative Team, Henry Brodaty (In press). Maintain Your Brain: protocol of a 3-year randomised controlled trial of an individualised multi-modal eHealth intervention to prevent cognitive decline and incident dementia amongst community dwelling 55-77 year olds. Journal of Alzheimer’s Disease.
Bahar-Fuchs A, Martyr A, Goh AMY, Sabates J, Clare L (2018). Cognitive training for people with mild to moderate dementia. Cochrane Database of Systematic Reviews 7:CD013069 [Full text]
Baker KS, Georgiou-Karistianis N, Lampit A, Valenzuela M, Gibson SJ, Giummarra MJ (2018). Computerised Training Improves Cognitive Performance in Chronic Pain: A Participant-Blinded Randomised Active-Controlled Trial with Remote Supervision. Pain 159:644-655 [PubMed]
Demetriou E, Lampit A, Quintana D, Naismith S, Song Y, Pye J, Hickie I, Guastella A (2018). Autism Spectrum Disorders: A meta-analysis of executive function. Molecular Psychiatry 23:1198-1204 [Full text]
Doniger MG, Schnaider-Beeri M, Bahar-Fuchs A, Gottlieb A, Tkachov A, Kenan H, Livny A, Bahat Y, Sharon H, Ben-Gal O, Cohen M, Zeilig G, Plotnik M (2018). Virtual reality-based cognitive-motor training for middle-aged adults at high Alzheimer's disease risk: A randomized controlled trial. Alzheimer’s & Dementia: Translational Research and Clinical Interventions27;4:118-129 [PubMed]
Webb SL, Loh V, Lampit A, Bateman J, Birney DP (2018). Meta-analysis of the effects of computerized cognitive training on executive functions: A cross-disciplinary taxonomy for classifying outcome cognitive factors. Neuropsychology Review 28:232-250 [PubMed]
Bahar-Fuchs A, Webb SL, Bartsch L, Clare L, Rebok G, Cherbuin N, Anstey KJ (2017). Tailored and adaptive computerised cognitive training in older adults at risk of dementia: A randomised controlled trial. Journal of Alzheimer’s Disease 60(3):889-911 [PubMed]
Bloom R, Schnaider-Beeri M, Ravona R, Heymann A, Dabush H, Bar L, Slater S, Rassovsky Y, Bahar-Fuchs A (2017). Computerized cognitive training for older diabetic adults at risk of dementia: study protocol for a double-blind randomized controlled trial. Alzheimer’s & Dementia: Translational Research and Clinical Interventions 3(4):636-650 [Full text]
Cross N, Lampit A, Pye J, Grunstein R, Marshall N, Naismith SL (2017). Is obstructive sleep apnoea related to neuropsychological function in healthy older adults? A systematic review and meta-analysis. Neuropsychology Review 27:389-402 [PubMed]
Hill N, Mowszowski L, Naismith S, Chadwick V, Valenzuela M, Lampit A (2017). Computerized Cognitive Training in Older Adults with Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis. The American Journal of Psychiatry 174:329-340 [Full text]
Masi A, Lampit A, DeMayo M, Glozier N, Hickie I, Guastella A (2017) A comprehensive systematic review and meta-analysis of pharmacological and dietary supplement interventions in pediatric autism: Moderators of treatment response and recommendations for future research. Psychological Medicine 47:1322-1344 [PubMed]
Stratton E, Lampit A, Choi I, Calvo RA, Harvey SB, Glozier N (2017). Effectiveness of eHealth interventions for reducing mental health conditions in employees: A systematic review and meta-analysis. PLoS One 12:e0189904 [Full text]
Walton C, Naismith S, Lampit A, Mowszowski L, Lewis S (2017). Cognitive Training in Parkinson’s Disease: A Theoretical Perspective. Neurorehabilitation and Neural Repair 31:207-216 [PubMed]
Hallock H, Collins D, Lampit A, Deol K, Fleming J, Valenzuela M (2016). Cognitive Training for Post-Acute Traumatic Brain Injury: A Meta-Analysis. Frontiers in Human Neuroscience, 10:537 [Full text]
Mowszowski L, Lampit A, Walton C, Naismith SL (2016). Strategy-Based Cognitive Training for Improving Executive Functions in Older Adults: A Systematic Review. Neuropsychology Review, 26:252-270 [PubMed]
Suo C, Fiatarone Singh M, Gates N, Wen W, Sachdev P, Brodaty H, Saigal N, Wilson G, Meiklejohn J, Singh N, Baune B, Baker M, Foroughi N, Wang Y, Mavros Y, Lampit A, Leung I, Valenzuela M (2016). Therapeutically Relevant Structural and Functional Mechanisms Triggered by Physical and Cognitive Exercise. Molecular Psychiatry 21:1633-1642 [Full text]
Anstey KJ, Bahar-Fuchs A, Herath P, Kim S, Burns R, Rebok G, Cherbuin N (2015). Body Brain Life: a randomized controlled trial of an online dementia risk reduction intervention in middle-aged adults at risk of Alzheimer's disease. Alzheimer's & Dementia: Translational Research & Clinical Interventions 1(1):72-80 [Full text]
Barnett J, Bahar-Fuchs A, Cherbuin N, Herath P, Anstey K (2015). Interventions to prevent cognitive decline and dementia in adults without cognitive impairment: A systematic review. Journal of Prevention of Alzheimer's Disease 2(1):38-45 [PubMed]
Lampit A, Hallock H, Suo C., Naismith S, Brodaty H, Valenzuela M. (2015) Cognitive training-induced short-term functional and long-term structural plastic change is related to gains in global cognition in healthy older adults. Frontiers in Aging Neuroscience 7:14 [Full text]
Leung I, Walton C, Hallock M, Lewis S, Valenzuela M, Lampit A (2015). Cognitive training in Parkinson’s disease: A systematic review and meta-analysis. Neurology 85:1843–1851 [Full text]
Masi A, Lampit A, Glozier N, Hickie I, Gustella A (2015). Predictors of placebo response in pharmaceutical and dietary supplement treatment trials in pediatric autism spectrum disorder: A meta-analysis. Translational Psychiatry 5:e640 [Full text]
Ong K, Villemagne V, Bahar-Fuchs A, Reininger C, Putz B, Rohde B, Masters C, Rowe C (2015). Aβ Imaging with 18F-Florbetaben in Prodromal Alzheimer’s Disease: A Prospective Outcome Study. Journal of Neurology, Neurosurgery & Psychiatry 86(4):431-6 [PubMed]
Lampit A, Ebster C, Valenzuela M (2014). Multi-domain computerized cognitive training program improves performance of bookkeeping tasks: A matched-sampling, active-controlled trial. Frontiers in Psychology 5:794 [Full text]
Lampit A, Hallock H, Moss R, Kwok S, Kohn A, Lukjanunko M, Rosser M, Naismith S, Brodaty H, Valenzuela M. (2014). The timecourse of global cognitive gains from supervised computer-assisted cognitive training: A randomised, active-controlled trial in elderly with multiple risk factors. Journal of Prevention of Alzheimer’s Disease 1:33-9 [PubMed]
Lampit A, Hallock H, Valenzuela M. (2014). Computerized cognitive training in cognitively healthy older adults: A systematic review and meta-analysis of effect modifiers. PLoS Medicine 11: e1001756 [Full text]
Anstey K, Bahar-Fuchs A, Cherbuin N, Herath M (2013). A 12-week multi-domain intervention versus active control to reduce risk of Alzheimer’s disease: Study protocol for a randomised controlled trial. Trials 14:60 [Full text]
Bahar-Fuchs A, Ong K, Villemagne V, Chetelat G, Lamb F, Woodward M, Rowe C (2013). Prediction of amyloid-β pathology in amnestic mild cognitive impairment with neuropsychological tests. Journal of Alzheimer's Disease 33(2):451-462 [PubMed]
Bahar-Fuchs, A., Woods R.T, Clare, L (2013). Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database of Systematic Reviews(6):CD003260 [Full text]
Bahar-Fuchs, A, Woods RT, Clare, L (2013). Cognitive training and cognitive rehabilitation for persons with mild to moderate dementia of the Alzheimer's or vascular type: A review. Alzheimer’s Research & Therapy5(4):35 [Full text]
Ong K, Villemagne V, Bahar-Fuchs A, Reininger C, Putz B, Rohde B, Masters C, Rowe C (2013). 18F-florbetaben Ab imaging in mild cognitive impairment. Alzheimer’s Research & Therapy 5:4 [Full text]
Bahar-Fuchs A, Moss S, Rowe C, Savage G (2011). Awareness of olfactory deficits in healthy ageing, amnestic mild cognitive impairment, and Alzheimer’s disease. International Psychogeriatrics 23(7):1097-1106 [PubMed]
Bahar-Fuchs A, Chételat G, Moss S, Pike K, Villemgne V, Masters C, Rowe C, Savage G (2010). Olfactory deficits and amyloid-β burden in Alzheimer's disease, mild cognitive impairment, and healthy aging: a PiB PET study. Journal of Alzheimer's Disease 22(4):1081-1087 [PubMed]
Bahar-Fuchs A, Moss S, Rowe C, Savage G (2010). Can I smell gas (or is it lilac)? Olfactory semantic deficits in Mild Cognitive Impairment and Alzheimer's disease. Chemosensory Perception 3(2):118-128 [Abstract]
Bahar-Fuchs A, Moss S, Rowe C, Savage G (2010). Olfactory performance in AD, aMCI, and healthy ageing: a unirhinal approach. Chemical Senses 35(9):855-862 [Full text]
Ponsford J, Hill B, Karamitsios M, Bahar-Fuchs A (2008). Factors influencing outcome after orthopedic trauma. The Journal of Trauma: Injury, Infection, and Critical Care64(4):1001-1009 [PubMed]
Ponsford J, Whelan R, Bahar-Fuchs A (2007) Alcohol and Drug Use Following Traumatic Brain Injury: A Prospective Study. Brain Injury21(13-14):1385-1392 [PubMed]