Do specific organ systems manifest poor health in individuals with common neuropsychiatric disorders?
New research published in JAMA psychiatry in April 2023 - Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders - Ye Ella Tian, MBBS, PhD; Maria A. Di Biase, PhD; Philip E. Mosley, MD, PhD ; et al.
This multicenter population-based cohort study including 85,748 adults with neuropsychiatric disorders and 87,420 healthy control individuals found that poor body health, particularly of the metabolic, hepatic, and immune systems, was a more marked manifestation of mental illness than brain changes. However, neuroimaging phenotypes enabled differentiation between distinct neuropsychiatric diagnoses. Management of serious neuropsychiatric disorders should acknowledge the importance of poor physical health and target restoration of both brain and body function.
Media mentions of some of the work led by Dr Tian appearing in the Age and the Sydney Morning Herald:
And another piece in the Australian [paywalled]: