CARISTA Overview
Creating A RIsk assessment biomarker tool to prevent Seasonal and Thunderstorm Asthma – CARISTA Study
ClinicalTrials.gov ID NCT07055542
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime.
The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
The goal of the CARISTA study is to identify the risk of springtime allergic and thunderstorm asthma in allergic adults living in South-Eastern Australia.
To do this the CARISTA Study will recruit 530 people who have hay fever and test them for allergy to ryegrass pollen and undertake simple breathing tests.
Importantly, the CARISTA Study asks participants to track their hay fever and asthma symptoms during the rye grass pollen season in south-eastern Australia (October to December) over 2 consecutive years using a secure electronic diary.
By tracking these symptoms, we aim to identify indicators (biomarkers) in the body that helps identify people at risk of worsening asthma and severe asthma during ryegrass pollen season.
This knowledge will contribute to developing targeted protective strategies and treatments to reduce the burden of springtime asthma in the community.
Funded by the Medical Research Future Fund [MRF2031254]