Recent Publication: Using AI and PET to study links between Tau and Amyloid proteins in the Brain.

Mapping the association between tau‑PET and Aβ‑amyloid‑PET using deep learning.

This Article in Scientific Reports can be accessed here.

Our team used our high-resolution PET scanner, to examine the Aβ-tau association using a convolutional neural network (CNN), and compared results to a standard voxel-wise linear analysis.   The investigation found at low Aβ levels, information from the middle cingulate, frontal lobe and precuneus regions was more predictive of Aβ burden, while at high Aβ levels, the medial temporal regions were more predictive of Aβ burden. The data-driven CNN approach revealed new associations between tau topography and Aβ burden.