Advanced Interventions in Mood Disorders Research Group

Group Lead

Professor Christopher Davey

Overview

The Advanced Interventions in Mood Disorders (AIM) Clinic provides adults with severe mood disorders access to novel treatments and innovative research projects.

Depressive disorders are common mental health conditions, affecting about one in 12 Australians.

While there are evidence-based treatments for depressive disorders, approximately one-third of people do not experience a significant or sustained improvement in their symptoms using these first-line treatments.

The AIM Clinic provides novel treatments and conducts innovative research projects that aim to reduce depressive symptoms and improve quality of life in people with difficult-to-treat mood disorders.

Current Research Projects

Interested in participating in research?

• The AMPA-VEGA 1 Study – clinical trial for depression
  A study for people with major depressive disorder, researching an investigational medication to assess its safety and whether it may improve symptoms of depression when taken alongside current antidepressant medication.
• The Kite Trial - ketamine for bipolar depression
  A randomised controlled trial investigating whether low-dose ketamine is an effective treatment for people with bipolar depression.
• Hearts & Minds - metformin and atorvastatin for adults with depression
  Hearts & Minds is a clinical trial to investigate whether metformin or atorvastatin help to reduce symptoms of depression.
• Neural Mechanism of Ketamine Antidepressant Treatment (NeuroKet) – brain imaging study for adults with depression
  NeuroKet is a neuroimaging study that aims to understand how ketamine works as an antidepressant medication.