The Target-D Trial

  • Project Leader

    Professor Jane Gunn
    T: +61 3 8344 4530
    E: j.gunn@unimelb.edu.au
    W: Personal web page

    Location: Department of General Practice, Primary Care Research Unit, 200 Berkeley Street, Carlton Victoria 3053.

Project Details

As the single largest cause of disability burden in Australia, depression results in lost employee productivity of over $2.7 billion per year. Depression is mainly managed in general practice. Using data from our successful diamond longitudinal cohort study we have developed the diamond clinical prediction tool (CPT) for use in primary care.

Using this tool the trial is testing the hypothesis that a stratified approach to the primary care management of depression will result in clinical and economic benefits compared to usual general practice care. The primary aim is to test whether stratifying patients into low, medium and high risk groups using the diamond CPT and offering targeted depression treatment will reduce depressive symptoms at 3 months compared to usual care. The secondary aims are to test differences between the intervention and usual care arms within each risk group in terms of physical and social functional  impairment, quality of life, health service use and cost-efficacy at 3 and 12 months.

Final results of the trial will be available in 2018.

Researchers

Professor Jane Gunn, Lead Investigator, Department of General Practice (University of Melbourne)
Dr Patty Chondros, Department of General Practice (University of Melbourne)
Dr Sandra Davidson, Department of General Practice (University of Melbourne)
Ms Amy Coe, Senior Research Assistant, Department of General Practice (University of Melbourne)
Ms Konstancja Densley, Data Manager, Department of General Practice (University of Melbourne)
Dr Susie Fletcher, Research Fellow, Department of General Practice (University of Melbourne)

Collaborators

Associate Professor Catherine Mihalopoulos, Deakin Health Economics (Deakin University)
Associate Professor Kelsey Hegarty, Department of General Practice (University of Melbourne)
Dr Alishia Williams, Social and Behavioural Science (University of Utrecht, Netherlands)
Professor Leon Sterling, School of Science, Engineering and Technology (Swinburne University of Technology)
Dr Antonette Mendoza, Department of Computing and Information Systems (University of Melbourne)
Professor Christopher Dowrick, Institute of Psychology, Health and Society (University of Liverpool, UK)
Professor Elizabeth Murray, Research Department of Primary Care and Population Health, eHealth Unit (University College London, UK)
Professor Frances Griffiths, Warwick Medical School (University of Warwick, UK)
Professor Gavin Andrews, School of Psychiatry, (University of New South Wales)
Dr Gilles Ambresin, Department of Psychiatry (University of Lausanne, Switzerland)
Dr Victoria Palmer, Department of General Practice (University of Melbourne)

Funding

The Target-D Trial is funded by an NHMRC Project Grant (2014)

Research Outcomes

Participatory design for development of a triage tool: the Target-D mobile application (Oral). Primary Health Care Research Conference. Adelaide, Australia. 29-31 July 2015.

Patient Experiences of Using iCBT Programs: One Size Does Not Fit All (Poster) Primary Health Care Research Conference. Adelaide, Australia. 29-31 July 2015.

Participatory design for development of a triage tool: the Target-D mobile application (Oral). North American Primary Care Research Group (NAPCRG) Annual Meeting.  Cancun, Mexico.  23 – 28 October 2015.

Research Group

Mental Health



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

General Practice

Unit / Centre

Mental Health