Medical Projects by Theme

Ageing

Groups / Projects	Research Lead	Dept / Centre
Adipocytes as Weapons of Bone Destruction: The bone as a War Zone	Professor Gustavo Duque	Medicine
AgeHAPPY: Healthy Ageing Project Population Youth-senior	Principal investigator Professor Cassandra Szoeke Study coordinator Monique Stagnitti	Medicine
An exploration of the experience of care at the end of life for patients with a history of illicit drug use: A qualitative medical record review	Prof Jennifer Philip	Medicine
Analysis of Synovial Fluid and Peripheral Blood Samples from Patients with Rheumatoid Arthritis and Using Patients with Osteoarthritis as Controls	A/prof Keith Lim	Medicine
Artificial intelligence in ophthalmology: from data to algorithm and real-world application	Professor Mingguang He	Surgery
Artificial intelligence system to detect eye and cardiovascular diseases	Professor Mingguang He	Surgery
Assessment of the Falls and Fractures Prevention Clinic as the Most Effective Setting toReduce Falls and Fractures in High-Risk Older Persons: A Care Program Assessment	Professor Gustavo Duque	Medicine
Associations Between Sarcopenia, Intramuscular Fat, Mental/Physical Function and Brain Atrophy: An Imaging and Machine Learning Approach	Professor Gustavo Duque	Medicine
Balance Gym for Falls Prevention in Older Adults	Professor Gustavo Duque	Medicine
Brain storming therapeutics for neurodegeneration with novel research models	A/Prof Brian Drew	Baker Department of Cardiometabolic Health
Characterization of Osteosarcopenia in Older Persons: A Bench to Bedside Approach	Professor Gustavo Duque	Medicine
Circulating Osteogenic Precurors: Building Bone from Blood	Professor Gustavo Duque	Medicine
Cognitive Interventions Technologies and Evaluation	Dr Amit Lampit	Psychiatry
Cognitive training for behavioural and psychological symptoms in young onset dementia	Dr Alex Bahar-Fuchs	Psychiatry
Core Outcomes in Menopause	Project Leader Professor Martha Hickey	Obstetrics and Gynaecology
Diet and Healthy Ageing	Professor Cassandra Szoeke	Medicine
Effective relationships in dementia community care: Promoting Independence though quality dementia care at home (the PITCH project).	Dr Anita Goh	Psychiatry
Elizabeth Vincan	Professor Elizabeth Vincan	Infectious Diseases
Elucidating the functional roles of CCL17 in obesity-associated osteoarthritis	Dr Adrian Achuthan	Medicine
Evaluating information resources for women considering elective egg freezing	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Evidence-Based Practice in the Management of Glaucoma Suspects	Dr Zhichao Wu	Surgery
Exploring how diabetes causes increased proliferation of haematopoietic stem cells carrying a mutation in DNMT3A	Prof Andrew Murphy	Baker Department of Cardiometabolic Health
Genotype and Phenotype Characterisation Human Circulating Osteo-Progenitor (COP) Cells	Professor Gustavo Duque	Medicine
How do bone marrow microenvironments regulate B lymphocyte production?	Professor Louise Purton	Medicine
Implementation of a Virtual Reality sensory room in a sub-acute ward for people living with dementia with behaviours and psychological symptoms associated with dementia (BPSD)	Dr Anita Goh	Psychiatry
Improved early diagnosis of eye diseases by integration of retinal photography and artificial intelligence to build an opportunistic screening service in metro, regional and remote primary care settings	Professor Mingguang He	Surgery
In Vivo Tibiofemoral Biomechanics in Healthy Adults During Functional Activity	Dr Hans Gray	Surgery
INDIGO Study: physical activity and goal-setting intervention for sedentary older adults at risk of cognitive decline	Principal Researcher Professor Nicola Lautenschlager (Melbourne Site)	Psychiatry
Influenza and other respiratory viruses	Research Group Leader Associate Professor Sheena Sullivan	Infectious Diseases
Investigating the relationship between fat, bone and muscle	Professor Gustavo Duque	Medicine
Irani Thevarajan	Dr Irani Thevarajan	Infectious Diseases
Karin Thursky	Professor Karin Thursky	Infectious Diseases
Let's CHAT Dementia	A/Prof. Dina LoGiudice	Medicine
Machine learning prediction of brain and body ageing	Associate Professor Andrew Zalesky	Psychiatry
Marrow Adipose Tissue Functions: Studying Lipotoxicity in Hip Replacement Candidates	Professor Gustavo Duque	Medicine
Mid-Thigh Bone and Muscle Mass Measurements as an Assessment Tool for Diagnosis of Osteoporosis/penia, Sarcopenia and Osteosarcopenia: A Longitudinal Validation Study	Professor Gustavo Duque	Medicine
Molecular Oncology	Research Group Leader Professor Elizabeth Vincan	Infectious Diseases
Multimedia (MyStay) Intervention for managing patient experience (MIME) following total hip replacement surgery: a cluster randomised trial.	Ms Jo McDonall	Surgery
Multimodal imaging measures to improve dementia diagnosis	Dr Vijay Venkatraman	Medicine
New methods for investigating bone muscle and fat mass using 2D DXA images to predict performance, risk of falls and fractures	Professor Gustavo Duque	Medicine
Novel regenerative therapies in cardiovascular diseases	Prof Karlheinz Peter	Baker Department of Cardiometabolic Health
Novel therapies for atherosclerotic plaque stabilization	Prof Karlheinz Peter	Baker Department of Cardiometabolic Health
Olfactory-focused cognitive training	Dr Alex Bahar-Fuchs	Psychiatry
Osteosarcopenia as a Geriatric Syndrome	Professor Gustavo Duque	Medicine
Osteosarcopenia in community-dwelling older adults attending the Falls and Fracture Clinic	Prof Gustavo Duque	Medicine
Osteosarcopenia in Older Adults Attending a Fracture Liaison Service	Dr. David Scott	Medicine
Palliative Nexus	Group Leader Professor Jennifer Philip	Medicine
Pathology begins in the cells: Studying lipotoxic stress generated from adipocytes in bone and muscle cell cultures	A/prof Damian Myers	Medicine
Pre-clinical Analysis of Effects of Lamin A Overexpression on Mesenchymal Stem Cell Differentiation into Myocytes	Professor Gustavo Duque	Medicine
Predicting Disability and Frailty in Older Persons: The Western Osteosarcopenia and Frailty (WOSF) Study	Prof Gustavo Duque	Medicine
Promoting and advancing midlife health in women	Project Leader Professor Martha Hickey	Obstetrics and Gynaecology
Quantitative imaging in dementia	Prof Patricia Desmond	Medicine
Quantitative Measure of Effusions	A/Prof Keith Lim	Medicine
RAndomised trial to imProve the quality of lIfe of people with Dementia (RAPID)	Principal Researcher rofessor Nicola Lautenschlager (Melbourne Site)	Psychiatry
Refining the comprehensive geriatric assessment	Prof. Andrea Maier	Medicine
Regulation of blood cell production by endothelial cell-derived retinoic acid receptor gamma	Professor Louise Purton	Medicine
Research at Epworth	Professor Richard de Steiger
Satellite imaging technology to detect the early signs of glaucoma and Alzheimer’s disease in the retina	A/Prof Peter van Wijngaarden	Surgery
Sheena Sullivan	Associate Professor Sheena Sullivan	Infectious Diseases
Social and physical activities in ageing women	Dr Jesse Zanker	Medicine
Synovial Knee Arthritis Research (SKAR)	Professor John Hamilton	Surgery
Synthesising, dismantling and optimising cognitive interventions	Dr Amit Lampit	Psychiatry
Taking the “Guesswork” Out of Glaucoma Clinical Management with Novel Imaging	Dr Zhichao Wu	Surgery
The Correlation between Knee Effusions and Clinical Presentation in Patients with Knee Osteoarthritis	A/Prof Keith Lim	Medicine
The relationship between cognitive impairment seen in chronic mental illness and dementia - what can mortality information tell us?	Dr Samantha Loi	Psychiatry
The Stand Up & Go Study: Physical activity and sitting time reduction program for older community members	Principal Researcher Professor Nicola Lautenschlager (Melbourne Site)	Psychiatry
Treatment outcome in older lung cancer patients: does the biological age predict it?	Prof. Andrea Maier	Medicine
Using Artificial Intelligence to improve the diagnostic predictions of corneal topography machines for Keratoconus subjects	Dr Srujana Sahebjada	Surgery
Using Marrow Adipose Tissue to Diagnose Osteoporosis and Predict Fragility Fractures	Professor Gustavo Duque	Medicine
Using Wearable Activity Trackers to Monitor Physical Activity in Older Adults Undergoing Exercise Interventions for Falls	Dr David Scott	Medicine
Your Muscles Matter – The Sarcopenia Study	A/Prof Alan Hayes	Medicine

Cancer in Medicine

Groups / Projects	Research Lead	Dept / Centre
A monoclonal antibody (mAb1F5) has been developed that identifies the expression of a putative growth factor	Dr Peter Wookey	Medicine
A mouse model of duodenal atresia	Project Leader Associate Professor Warrick Teague	Paediatrics
A New reagent for detection of program cell death	Dr Peter J Wookey	Medicine
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer		Medicine
A systematic review of end of life quality of care indicators	Prof Jennifer Philip	Medicine
A systematic review of the management of sleep in palliative care cancer patients	Prof Jennifer Philip	Medicine
A therapeutic strategy for killing cancer cells by DNA repair inhibition	A/Prof Andrew Deans	Medicine
A5 SDHB Genomics Study	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Academic Department of Surgery, Western Health	Associate Professor Justin Yeung	Surgery
ACRF Translational Research Laboratory	Group Leader Professor David S Ritchie	Medicine
Advanced Limb Reconstruction	Head of Department of Surgery, St. Vincent's Hospital, Professor Peter Choong	Surgery
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism	Dr Peter Wookey	Medicine
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines.	Dr Peter J Wookey	Medicine
Boussioutas Laboratory: Gastrointestinal Cancer	Group Leader Professor Alex Boussioutas	Medicine
Brain Cancer Invasion Group	Dr Stanley Stylli	Surgery
Brain Cancer Microenvironment and Biology Laboratory	Dr Theo Mantamadiotis	Surgery
Brain Tumours and Epilepsy	Associate Professor Andrew Morokoff	Surgery
Breast Cancer	Head of Group Professor Bruce Mann Lead Researcher Dr Anita Skandarajah	Surgery
Buchanan laboratory: Oncogenomics (colorectal cancer)	Head of Laboratory Associate Professor Daniel Buchanan	Clinical Pathology
Coin Laboratory: Cancer Bioinformatics	Head of Laboratory Professor Lachlan Coin	Clinical Pathology
Cancer Biology Research Group	Professor Graham Baldwin	Surgery
Cancer drug discovery by inhibition of a DNA repair pathway with Crispr/Cas9 gene editing and biochemistry	Dr Wayne Crismani	Medicine
Cancer Immunotherapy symptoms: the experience and expectations around management	Program Trial Coordinator Leeanne Pasanen	Medicine
Cancer in Primary Care	Research Program Leader Professor Jon Emery	General Practice
Cancer Signaling Research Laboratory	Dr Hong-Jian Zhu	Surgery
Cardiovascular and Tumourivascular Laboratory	Dr Peter J Wookey Professor David Hare	Medicine
Care Plus Study	Research Assistant Roslyn Le Gautier	Medicine
Centre for research excellence in cervical cancer control		Obstetrics and Gynaecology Research
Characterisation of complex structural variation in bacterial and human genomes	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Characterising Respiratory Infections in Immune-suppressed Haematology and Transplant Patients	Professor Monica Slavin	Medicine
CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Circulating Biomarkers in Liver Malignancy	Professor Christopher Christophi	Surgery
CRISP-DNA: The feasibility of assessing bowel cancer risk using genomic testing to target screening in general practice	Herman Professor of Primary Care Cancer Research Professor Jon Emery	General Practice
Defining the Role of Transcriptional Stress Pathways in Cancer Cell Resistance Towards Anti-Cancer Therapeutics	A/prof John Price	Medicine
Developing clinical genomic methods for cancer of unknown primary	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Development and validation of triage guidelines for colonoscopy and gastroscopy		General Practice
Elizabeth Vincan	Professor Elizabeth Vincan	Infectious Diseases
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids	Dr Adrian Achuthan	Medicine
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit	Research Group Leader Dr Michelle Peate	Obstetrics and Gynaecology
Endocrine Surgery	Associate Professor Julie Miller	Surgery
Enhance: A multi-centre, randomised phase IV study		Medicine
Enteric Neuropathy as a Target to Alleviate Gastrointestinal Side-effects of Chemotherapy	A/prof Kulmira Nurgali	Medicine
Establishing patterns of primary health care usage in cancer at the end of life	Matthew Grant	Medicine
Evaluating molecular biomarkers of anal cancer risk		Obstetrics and Gynaecology
Exploring the effects of human papillomavirus (HPV) vaccination on diversity of circulating genotypes	Dr Reza Haqshenas	Obstetrics and Gynaecology
Fertility After Cancer Predictor (FoRECAsT) Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Fertility decision tools for young women with breast cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer	Senior Lecturer Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Fertility preservation in children with cancer	Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Finding a needle in the haystack: ctDNA detection for tracking cancer evolution and refining cancer risk	Associate Professor Daniel Buchanan	Clinical Pathology
Function and cryo-EM structure of the breast cancer predisposition gene BRCA1	A/Prof Andrew Deans	Medicine
Gene regulation in the developing retina and the childhood eye cancer retinoblastoma	Prof David Eisenstat	Paediatrics
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Glioblastoma Survival Signaling Lab	Dr Rodney Luwor	Surgery
Gynaecology Research Centre - Hickey Group	Research Group Leader Professor Martha Hickey	Obstetrics and Gynaecology
Head and Neck Tumour Stream Research Group	Professor David Wiesenfeld	Surgery
Heterogeneity of treatment response in advanced cancer: role of intrinsic and microenvironmental factors	AProfessor Frederic Hollande	Clinical Pathology
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer	Head of Laboratory Professor Fred Hollande	Clinical Pathology
Honorary Appointments’ Research Projects		Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance	Professor Christopher Christophi	Surgery
Human Liver Organoids	Project Lead Professor Kumar Visvanathan	Medicine
Identification and Characterisation of Molecular Mediators of Cancer Metastasis	A/prof John Price	Medicine
Identification of biomarkers for diagnosis and prognosis human papillomavirus associated cancer	DR Gerald Murray	Obstetrics and Gynaecology
Identifying and characterising Lynch syndrome within the population	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying better therapies for patients with myelodysplastic syndromes.	Professor Louise Purton	Medicine
Identifying biomarkers of risk and poor prognosis in CRC	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Improving reproductive health through infectious diseases research		Obstetrics and Gynaecology
Inflammation-induced Cancer: Mechanisms and Novel Treatments	A/prof Kulmira Nurgali	Medicine
Informal Communities in Cancer Treatment	Project Lead Dr Matt Grant	Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David S Ritchie	Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David Ritchie	Medicine
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer	Group Leader, acting Head of Department Associate Professor Fred Hollande	Clinical Pathology
Investigating the link between phenotype change and treatment resistance in prostate cancer	Associate Professor Niall Corcoran	Surgery
Linking determination of cell fate in the developing nervous system to paediatric brain tumours	Prof David Eisenstat	Paediatrics
Liver Group	Professor Christopher Christophi	Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Project Lead Dr Rachel Koldej	Medicine
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Prof David Ritchie	Medicine
Manometric studies on oesophageal atresia and colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
Mesenchymal Stem Cell-based Therapies for Inflammatory Bowel Disease and Colorectal Cancer	A/prof Kulmira Nurgali	Medicine
Metastasis Research Group	Professor Albert G Frauman	Medicine
Molecular Mechanisms of Tumour Resistance Laboratory	Dr Rodney Luwor	Surgery
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland	Obstetrics and Gynaecology
Molecular signalling pathways controlling gene expression during chronic disease progression	Dr Adrian Achuthan	Medicine
Neurosurgery	Professor Kate Drummond	Surgery
NHMRC Centre for Research Excellence for Reducing the Burden of Colorectal Cancer by Optimising Screening	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Novel Approaches in Therapeutic Endoscopy	A/prof Alan Moss	Medicine
Novel genetic interactions with the double-stranded RNA-induced autoimmunity pathways	A/Prof Carl Walkley	Medicine
Novel investigations and treatments for intractable, chronic constipation	Project Leader Dr Bridget Southwell	Paediatrics
Novel treatments for colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
OPPtiC: A pilot feasibility study of establishing a clinical opioid pharmacogenomics database in palliative care	Program Trial Coordinator Leeanne Pasanen	Medicine
Optimising the management of patients awaiting liver transplantation	Professor Christopher Christophi Senior Lecturer Michael Fink	Surgery
PaCCSC RAPID Series - Cancer-related Lymphoedema	Beth Russell	Medicine
Paediatric and Adolescent Fertility Preservation Taskforce	Senior Lecturer Yasmin Jayasinghe	Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Palliative Nexus	Group Leader Professor Jennifer Philip	Medicine
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility	Project Leader Dr Ruili Li	Paediatrics
Prevalence of Risk Factors for Melanoma in Primary Care Patients using the MelaTools Risk Calculator	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research,	General Practice
Priorities and Needs of Women Living with Advanced Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Probiotic therapy		Obstetrics and Gynaecology
Promoting and advancing midlife health in women	Project Leader Professor Martha Hickey	Obstetrics and Gynaecology
Prostate Cancer	Head of Group Professor Christopher Hovens Deputy Laboratory Head Associate Professor Niall Corcoran	Surgery
Prostate cancer progression inhibition	Group Leader Professor Albert G Frauman	Medicine
Prostate Cancer Research Group	Professor Christopher Hovens	Surgery
RAPID Postmarketing Study - Medicinal Cannabis		Medicine
Rare Disease Oncogenomics	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Professor David Ritchie	Medicine
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Group Leader Professor David Ritchie	Medicine
Reducing disparities in mortality and survival for rural Victorians with colorectal cancer	Rebecca Bergin	General Practice
Regulation of blood cell production by endothelial cell-derived retinoic acid receptor gamma	Professor Louise Purton	Medicine
Regulation of cancer stem cell self-renewal in colorectal cancer	Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande	Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion	Dr Stanley Stylli	Surgery
Renal supportive care of patients with advanced chronic kidney disease	Kathryn Ducharlet	Medicine
Reproductive Steroids Research Group	Professor Mathis Grossmann, MD, PhD, FRACP	Medicine
The role of the essential biometal zinc in pathological and physiological processes	Professor Graham Baldwin Dr Oneel Patel Dr Joseph Ischia	Surgery
Role of p-21-activated kinases in pancreactic cancer	Professor Graham Baldwin Dr Mehrdad Nikfarjam	Surgery
Role of the Nervous System in Cancer Development and Progression	A/prof Kulmira Nurgali	Medicine
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection	Professor Christopher Christophi	Surgery
Roles of macrophages subpopulations in tumour microenvironment in gastric cancer	Dr Adrian Achuthan	Medicine
Roles of macrophages subpopulations in tumour microenvironment in gastric cancer	Dr Adrian Achuthan	Medicine
Roles of mammary adipose macrophages in breast cancer	Dr Adrian Achuthan	Medicine
Serum biomarkers of brain cancer	Dr Andrew Morokoff	Surgery
Spinal Biology Laboratory	Doctor Gerald Quan	Surgery
STEP Care Clinical Trial	Project Lead Anna Collins	Medicine
Structural biology of proteins involved in cancer	Dr Craig Morton	Medicine
Studying the Continuum of Cancer Care through Linking Primary Data	Research Project Leader Professor Jon Emery	General Practice
Supporting earlier cancer diagnosis and efficient referral pathways in general practice		General Practice
Surgical Research Group	Chair of Paediatric Surgery Professor John M Hutson AO	Paediatrics
Systematic EndoscopIc Staging of Mediastinum to determine Impact on radiotherapy for locally advanced lung Cancer (SEISMIC): an international multi-centre cohort study	Associate Professor Daniel Steinfort	Medicine
T cell function as a determinant of blinatumomab efficacy in B-ALL	Group Leader Professor David Ritchie	Medicine
T cell function as a determinant of blinatumomab efficacy in B-ALL	Professor David Ritchie	Medicine
Targeting the angiogenic and osteoclastic pathways in spinal cancer	Doctor Gerald Quan Doctor Gerald Quan	Surgery
Targeting the Lymphatics in colorectal Liver metastasis	Professor Christopher Christophi	Surgery
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production	Professor Michael McCullough	Surgery
The CGA-Oncology Study: Comprehensive geriatric assessment and intervention in older lung cancer patients	Project Lead Professor Andrea B Maier	Medicine
The characterisation of CT Receptor expression in the CNS and perinatal PNS: the distribution, intracellular associations and functions of isoforms.	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer.	Dr Peter J Wookey	Medicine
The Genomic Drivers of High Risk Prostate cancer	Professor Christopher Hovens	Surgery
The impact of cancer therapies on the bone marrow microenvironment	Professor Louise Purton	Medicine
The role of Critical Signalling Pathways in Glioblastoma Mediated Immunosuppression	Dr Adrian Achuthan	Medicine
The role of EGFR Signaling in Glioblastoma Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The role of FANCM gene in inherited breast cancer	A/Prof Andrew Deans	Medicine
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of miRNA in oral mucosal disorders	Professor Michael McCullough	Surgery
The role of RECQL4 gene in cancer predispositon	Dr Andrew Deans	Medicine
The role of RNA editing enzyme ADAR1 in liver homeostasis and metabolism	A/Prof Carl Walkley	Medicine
The role of STAT3-mediated Cancer Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The treatment of the brain tumour glioblastoma (GBM): the efficacy of immunotoxin derived from anti-calcitonin receptor antibodies	Dr Peter J Wookey	Medicine
Treatment outcome in older lung cancer patients: does the biological age predict it?	Prof. Andrea Maier	Medicine
Ultrasound	Group Leader Professor Robert N Gibson	Medicine
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Prof David Ritchie	Medicine
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Professor David S Ritchie	Medicine
Understanding the aetiology of Serrated Polyposis Syndrome	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma	Surgeon, Project Leader Dr David Gyorki	Surgery
Understanding the microenvironment of lymphodema	Dr Ramin Shayan	Surgery
Understanding the role of CXCR7 in lymphodema following radiation injury	Dr Ramin Shayan	Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism	Project Leader Professor John M Hutson AO	Paediatrics
Unravelling the causes of persistent exercise intolerance in cancer survivors	Dr Steve Foulkes	Baker Department of Cardiometabolic Health
Use of Connexin43 peptides as a treatment for glioma	Dr Stanley Stylli	Surgery
VCCC Building Capability in Clinical Trials Program	Program Trial Coordinator Leeanne Pasanen	Medicine
Western Health Cancer Research	Group Leader Professor Michael Green	Medicine
WomenCAN: Promoting and advancing women’s health and wellbeing after cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study.	Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey	Obstetrics and Gynaecology

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Cardiometabolic

Groups / Projects	Research Lead	Dept / Centre
: Unravelling the role of breast milk ether lipids in modulating immune function in early life	Professor Peter Meikle	Baker Department of Cardiometabolic Health
A monoclonal antibody (mAb1F5) has been developed that identifies the expression of a putative growth factor	Dr Peter Wookey	Medicine
A New reagent for detection of program cell death	Dr Peter J Wookey	Medicine
A novel approach in improving lipidomics throughput for population profiling	Professor Peter Meikle	Baker Department of Cardiometabolic Health
Activated platelets targeted drug therapy	Dr Xiaowei Wang	Baker Department of Cardiometabolic Health
Additional Signals	Project Lead Professor David O'Neal	Medicine
Adipocyte Biology, Insulin Resistance and Cardiovascular Disease	Group Leader Associate Professor Andrew Wilson	Medicine
Adult Hybrid Closed Loop Study	Project Lead Professor David O'Neal	Medicine
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism	Dr Peter Wookey	Medicine
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines	Dr Peter J Wookey	Medicine
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines.	Dr Peter J Wookey	Medicine
Application of computational biology approaches to identify and develop biomarkers to predict pregnancy disorders and guide clinical practice.	Professor Eva Dimitriadis	Obstetrics and Gynaecology
Arterial grafting for coronary artery revascularisation	Co-director Colin Royse	Surgery
Artificial intelligence system to detect eye and cardiovascular diseases	Professor Mingguang He	Surgery
Assessing the therapeutic effects of plasmalogen supplementation in a mouse model of heart failure	Dr Yow Keat Tham	Baker Department of Cardiometabolic Health
Atherothrombosis and Vascular Biology Group	Head of Laboratory Professor Karlheinz Peter Peter	Baker Department of Cardiometabolic Health
Baker Department of Cardiometabolic Health Research		Baker Department of Cardiometabolic Health
Biomarkers of Atherosclerosis	Group Leader Associate Professor Andrew Wilson	Medicine
Biomedical Translational Research Group: Developing Therapies for Cardiovascular Disease	Group Leader Professor Darren Kelly	Medicine
Brain storming therapeutics for neurodegeneration with novel research models	A/Prof Brian Drew	Baker Department of Cardiometabolic Health
Cardiac Cellular Systems	Laboratory Head Dr Alexander Pinto	Baker Department of Cardiometabolic Health Research
Cardiac Hypertrophy Group	Head of Laboratory Professor Julie McMullen	Baker Department of Cardiometabolic Health
Cardiothoracic Surgery	Professor Alistair Royse	Surgery
Cardiovascular and Tumourivascular Laboratory	Dr Peter J Wookey Professor David Hare	Medicine
Cardiovascular Inflammation and Redox Biology	Head of Laboratory Professor Judy de Haan	Baker Department of Cardiometabolic Health Research
Chronic Kidney Disease in the Management of people with Type 2 Diabetes in General Practice	Project Leader Dr Jo-Anne Manski-Nankervis	General Practice
Clinical Diabetes and Epidemiology Group	Deputy Director (Clinical and Population Health), Baker Institute Professor Jonathan Shaw	Baker Department of Cardiometabolic Health Research
Closing the Gap on Aboriginal Cardiovascular Health disparities- Using Big Data to understand the patient health journey	Associate Professor Luke Burchill	Medicine
Cognitive Health	Project Leader Professor Cassandra Szoeke	Medicine
Common severe childhood infections, innate inflammatory responses and cardiometabolic risk: The VASCular changes aFter INfectious Diseases (VASCFIND) study	Prof David Burgner	Paediatrics
Detecting the tissue of origin of circulating cell free DNA	Professor Lachlan Coin	Clinical Pathology
Developing epigenetic biomarkers to predict pregnancy disorders and guide clinical practice.	Prof Eva Dimitriadis	Obstetrics and Gynaecology
Developing nanoparticles for targeted theranostics delivery of drug and gene therapeutics	Dr Xiaowei Wang	Baker Department of Cardiometabolic Health
Developing novel therapies for the treatment of retinal disease	Professor Darren Kelly Project Lead Dr Amanda Edgley	Medicine
Developing platelet derived nanoparticles for targeted thrombolysis	Prof Karlheinz Peter	Baker Department of Cardiometabolic Health
Development and validation of a high throughput clinical lipidomics platform	Professor Peter Meikle	Baker Department of Cardiometabolic Health
Development of novel therapeutics to prevent or treat preeclampsia	Associate Professor Natalie Hannan	Obstetrics and Gynaecology
Diabetes and Cardio-Metabolic Conditions	Research Program Leader Associate Professor John Furler	General Practice
Diabetes and Obesity	Associate Professor Elif Ekinci	Medicine
Diabetes Discovery - prevalence and outcomes in inpatients with diabetes	Project Leader Dr Elif Ekinci	Medicine
Diabetes Technology Research Group	Group Leader Professor David O'Neal	Medicine
Diabetic Retinopathy Research Group	Group Leader Dr Laima Brazionis	Medicine
Diagnosis and therapy of inflammatory diseases using molecular ultrasound imaging	Dr Xiaowei Wang	Baker Department of Cardiometabolic Health
Digital Health	Group Leader Chris Ryan	Medicine
Do short chain fatty acids prevent gut leakiness and enhanced haematopoiesis induced by a high salt diet?	Prof Andrew Murphy	Baker Department of Cardiometabolic Health
Does epicardial adipose tissue contribute to atrial fibrillation in endurance athletes?	Dr Erin Howden	Baker Department of Cardiometabolic Health
Drug development for metabolic diseases	A/Prof Jon Oakhill	Medicine
Dyslipidemia Decision Support		Medicine
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids	Dr Adrian Achuthan	Medicine
Elucidating the functional roles of CCL17 in obesity-associated osteoarthritis	Dr Adrian Achuthan	Medicine
Engineering a tissue flap	Dr Geraldine Mitchell	Surgery
Evaluation of cardio-metabolic effects of Incretin-based therapies in type 2 diabetes	Project Lead Professor Sanjoy Paul	Medicine
Evaluation of the obesity paradox in diabetes: A longitudinal case-control study of half a million patients	Project Lead Professor Sanjoy Paul	Medicine
Exploring how a high salt diet promotes bone destruction through immune cell activation	Prof Andrew Murphy	Baker Department of Cardiometabolic Health
Exploring how diabetes causes increased proliferation of haematopoietic stem cells carrying a mutation in DNMT3A	Prof Andrew Murphy	Baker Department of Cardiometabolic Health
Exploring innate immune memory	Dr Andrew Fleetwood	Medicine
Exploring the therapeutic potential of protein phosphatases in cardiometabolic disease	Dr Kate Weeks	Baker Department of Cardiometabolic Health
Factors that determine islet antigen-specific T cell expansion before the onset of Type 1 diabetes	Prof Helen Thomas	Medicine
Future Health Today - health informatics	Associate Professor Jo-Anne Manski-Nankervis	General Practice
Future Health Today Changing the course of cardiovascular disease	Associate Professor Jo-Anne Manski-Nankervis	General Practice
Gene signatures of the ‘lymphaticome’	Dr Ramin Shayan Dr Tara Karnezis	Surgery
Genomics of asthma mortality due to thunderstorm asthma	Prof Jo Douglass	Medicine
Haematopoesis and Leukocyte Biology Group	Head of Laboratory Associate Professor Andrew Murphy	Baker Department of Cardiometabolic Health
Heart Health in Women: Role of Physical Activity to Prevent Cardiovascular Disease	Dr Erin Howden	Baker Department of Cardiometabolic Health
Human Integrative Physiology	Head of Laboratory Dr Erin Howden	Baker Department of Cardiometabolic Health
Hypoglycaemia and its consequences	Project Lead Professor Sanjoy Paul	Medicine
Identification of additional markers of ferroptosis with mass spectrometry	Professor Peter Meikle	Baker Department of Cardiometabolic Health
Imaging	Project Leader Monique Stagnitti	Medicine
Immunity, Chronic Inflammation and Cardiovascular Disease	Professor Karlheinz Peter	Baker Department of Cardiometabolic Health
Inhibition of microglia inflammation by AMPK for obesity treatment	Dr Sandra Galic	Medicine
Integration of population level ‘omics data to target cardiometabolic disease	Professor Peter Meikle	Baker Department of Cardiometabolic Health
Investigating a novel mechanism for improving beta-cell function in type 2 diabetes	Dr Kim Loh	Medicine
Investigating cardiovascular disease in Friedreich's ataxia using human induced pluripotent stem cells	Dr Shiang (Max) Lim	Surgery
Irani Thevarajan	Dr Irani Thevarajan	Infectious Diseases
Islet Biology & Metabolism Group	A/Professor Sof Andrikopoulos	Medicine
Lifestyle and Prevention	Project Leader Dr Edward Hill	Medicine
Lifestyle Factors and Cognitive Health	Professor Cassandra Szoeke	Medicine
Lipid Metabolism and Cardiometabolic Disease Group	Head of Laboratory Associate Professor Anna Calkin	Baker Department of Cardiometabolic Health
Lipidomic Profiling of Atrial Fibrillation Progression in a Murine Model	Dr Yow Keat Tham	Baker Department of Cardiometabolic Health
Lipoproteins and Cardiovascular Risk from Mid- to Late-life in Women	Senior Research Fellow Alexandra Gorelik	Medicine
Management of acute decompensated heart failure in inpatients with diabetes	Project Leader Dr Elif Ekinci	Medicine
Mechanotransduction in blood cells and consequences for thrombosis and inflammation	Professor Karlheinz Peter	Baker Department of Cardiometabolic Health
Mental Health	Project Leader Professor Lorraine Dennerstein	Medicine
Metabolomics Group	Head of Laboratory Professor Peter Meikle	Baker Department of Cardiometabolic Health
Modelling cardiovascular diseases using human cardiac organoids	Doctor Shiang Lim	Surgery
Molecular Imaging and Theranostics Group	Head of Laboratory Dr Xiaowei Wang	Baker Department of Cardiometabolic Health
Molecular Metabolism and Ageing Group	Head of Laboratory Associate Professor Brian Drew	Baker Department of Cardiometabolic Health
Molecular signalling pathways controlling gene expression during chronic disease progression	Dr Adrian Achuthan	Medicine
Multimorbidity in Ageing	Project Leader Dr Kate Gregorevic	Medicine
Multimorbidity and glycaemia in people with type 2 diabetes attending Australian general practice: a cross-sectional study utilising data from NPS MedicineInsight	Principal Investigator A/Prof Jo-Anne Manski-Nankervis	General Practice
Musculoskeletal and Bone Health	Project Leader Dr Raquel Pedrero-Chamizo	Medicine
Non-alcoholic fatty liver disease – characterising disease features in order to develop new therapies	Dr Amanda Edgley	Medicine
Novel regenerative therapies in cardiovascular diseases	Prof Karlheinz Peter	Baker Department of Cardiometabolic Health
Novel therapies for atherosclerotic plaque stabilization	Prof Karlheinz Peter	Baker Department of Cardiometabolic Health
Novel therapies for the treatment of cardiorenal disease	Project Lead Dr Andrew Kompa	Medicine
Novel therapies for the treatment of cardiorenal syndrome	Dr Andrew Kompa	Medicine
Novel therapies for the treatment of cardiovascular disease	Professor Darren Kelly Project Lead Dr Amanda Edgley	Medicine
Obesity	Dr Priya Sumithran	Medicine
Pathophysiology of glycaemic and cardiovascular risk factors in diabetes	Project Lead Professor Sanjoy Paul	Medicine
Plasmalogen modulation as a therapeutic approach for fatty liver disease	Professor Peter Meikle	Baker Department of Cardiometabolic Health
Point of Care Ultrasound Simulation Education	Dr David Canty	Surgery
Quality of Life	Project Leader Dr Katherine Campbell	Medicine
Refining the comprehensive geriatric assessment	Prof. Andrea Maier	Medicine
Data interoperability for remote patient monitoring		Medicine
Artificial Intelligence-assisted Retinal Photography		Medicine
Roles of macrophages subpopulations in tumour microenvironment in gastric cancer	Dr Adrian Achuthan	Medicine
Singing for breathing in people with severe non-malignant, chronic lung diseases	Assoc Prof Natasha Smallwood	Medicine
SMS Diabetes Education		Medicine
Sympathetic activation in adults with inadequate sleep	Dr Stephanie Yiallourou	Baker Department of Cardiometabolic Health
Targeting inflammation and fibrosis for the treatment of retinal disease	Dr Roy Kong	Medicine
Targeting Pyroptosis to improve diabetic cardiovascular disease.	Prof Judy de Haan	Baker Department of Cardiometabolic Health
The cellular fuel gauge: Novel mechanisms of metabolic control	A/Prof Jon Oakhill	Medicine
The characterisation of CT Receptor expression in the CNS and perinatal PNS: the distribution, intracellular associations and functions of isoforms.	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer.	Dr Peter J Wookey	Medicine
The effect of ageing and sex differences on heart recovery following a heart attack	Associate Professor Anna Calkin	Baker Department of Cardiometabolic Health
The GP-OSMOTIC trial: Continuous Glucose Monitoring in Type 2 Diabetes	Project Leader Associate Professor John Furler	General Practice
The role of AMP-activated kinase in suppressing atherosclerosis	Dr Kim Loh	Medicine
The treatment of the brain tumour glioblastoma (GBM): the efficacy of immunotoxin derived from anti-calcitonin receptor antibodies	Dr Peter J Wookey	Medicine
Trans Health Research	Dr Ada Cheung	Medicine
Translational Cardiovascular Biology	Group Leader Associate Professor Andrew Wilson	Medicine
Transoesophageal echoardiography in cardiac surgery	Co-director Colin Royse	Surgery
Treating fibrosis and inflammation to prevent end-organ damage in diabetes	Dr Roy Kong	Medicine
Treatment outcome in older lung cancer patients: does the biological age predict it?	Prof. Andrea Maier	Medicine
Type I interferon as a novel endogenous trigger of trained immunity	Dr Andrew Fleetwood	Baker Department of Cardiometabolic Health
Ultrasound Education Group	Co-director Professor Colin Royse Co-director Professor Alistair Royse	Surgery
Understanding antibiotic prescribing and use of guidelines in general practice – the GP National Antimicrobial Prescribing Survey (GP NAPS) pilot study	Principal Investigator Dr Jo-Anne Manski-Nankervis	General Practice
Understanding how Type 17 immunity and IL-17 cytokines regulate Type 1 diabetes	Dr Andrew Sutherland	Medicine
Unravelling the causes of persistent exercise intolerance in cancer survivors	Dr Steve Foulkes	Baker Department of Cardiometabolic Health
Using the JAK1/JAK2 Inhibitor Baricitinib to treat new-onset Type 1 diabetes	Prof Helen Thomas	Medicine
Validation of 4D Flow with Exercise using CMR	Doctor Ben Costello	Baker Department of Cardiometabolic Health
Vascular Health	Project Leader Professor Philippe Lehert	Medicine
What are antigens/epitopes are recognized in by islet-infiltrating CD8+ T cells in people with type 1 diabetes?	A/Prof Stuart Mannering	Medicine

133

Child Health in Medicine

Groups / Projects	Research Lead	Dept / Centre
: Unravelling the role of breast milk ether lipids in modulating immune function in early life	Professor Peter Meikle	Baker Department of Cardiometabolic Health
A clinical trial-in-a-dish using iPSC-derived cartilage and bone organoids	A/Prof Shireen Lamande	Paediatrics
A high throughput drug screen to identify candidate targets for the treatment of Neurofibromatosis Type 1.	Dr Kiymet Bozaoglu	Paediatrics
Adverse health consequences of infant food allergy: a population-based longitudinal study.	Dr Rachel Peters	Paediatrics
Antibiotic stewardship and related polices impact on child health outcomes	Dr Yanhong Jessika Hu	Paediatrics
Antibiotic stewardship and related polices impact on child health outcomes	Dr Yanhong Jessika Hu	Paediatrics
Application of computational biology approaches to identify and develop biomarkers to predict pregnancy disorders and guide clinical practice.	Professor Eva Dimitriadis	Obstetrics and Gynaecology
Application of CRISPR-Cas9 gene editing to treat childhood syndromes	A/Prof Andrew Deans	Medicine
Assessment and management of fatigue following paediatric acquired brain injury	Dr Sarah Knight	Paediatrics
Beverley Ann-Biggs	Professor Beverley Ann-Biggs	Infectious Diseases
Biomarker Discovery Group	Associate Professor Harry Georgiou	Obstetrics and Gynaecology
Can dietary phytophenols improve pregnancy outcomes?	Associate Professor Martha Lappas	Obstetrics and Gynaecology
Cerebral Palsy Research	Group Leader Professor Dinah Reddihough	Paediatrics
Changing the Trajectories of Australia's Most Vulnerable Children- The Early Years Education Program Randomised Controlled Trial	Professor Jeff Borland	Paediatrics
Chromosome disorders	Professor David Amor	Paediatrics
Clinical features in a common inherited cause of kidney failure	Professor Judy Savige	Medicine
Cluster RCT of a multi-component intervention package to improve maternal and childhood vaccination in Victoria	A/Prof Margie Danchin	Paediatrics
Common severe childhood infections, innate inflammatory responses and cardiometabolic risk: The VASCular changes aFter INfectious Diseases (VASCFIND) study	Prof David Burgner	Paediatrics
Community Child Health Group	Group Lead Professor Sharon Goldfeld	Paediatrics
Community Study of the Genetics of Autism Spectrum Disorder	Project Lead Professor Ingrid Scheffer	Medicine
Concussion Essentials: A clinical trial for reducing persisting symptoms after child concussion	Professor Vicki Anderson	Paediatrics
Controlling nephron patterning and segmentation in kidney organoids	Prof Melissa Little	Paediatrics
Detection and prevention of tuberculosis in children and adolescents in endemic, resource-limited settings	Project Leader Professor Steve Graham	Paediatrics
Developing computational approaches to analyse development and disease	Prof Melissa Little	Paediatrics
Developing epigenetic biomarkers to predict pregnancy disorders and guide clinical practice.	Prof Eva Dimitriadis	Obstetrics and Gynaecology
Developing high content screens of novel treatments for congenital nephrotic syndrome	Prof Melissa Little	Paediatrics
Developing novel methods for the diagnosis of tree nut allergies	Dr Kirsten Perrett	Paediatrics
Development of malaria transmission blocking drugs.	Dr Matthew Dixon	Infectious Diseases
Development of novel human stem cell derived models of beta-propeller protein-associated neurodegeneration for disease modelling and drug screening	A/Prof Paul Lockhart
Development of novel human stem cell derived models of beta-propeller protein-associated neurodegeneration for disease modelling and drug screening	Prof Paul Lockhart	Paediatrics
Development of novel point-of-care diagnostics tests and surveillance tools for malaria	Prof James Beeson	Medicine
Development of novel vaccines against malaria	Prof James Beeson	Medicine
Diabetic Retinopathy Research Group	Group Leader Dr Laima Brazionis	Medicine
Discovering the mechanisms and targets of immunity against malaria	Prof James Beeson	Medicine
Discovery of new treatments for brain development disorders linked to epigenetic regulatory genes	A/Prof Paul Lockhart	Paediatrics
Dose optimisation of antibiotics in children with cystic fibrosis	Dr Amanda Gwee	Paediatrics
Effects of Vitamin D Status on DEXA Femoral Neck BMD in Children and Adolescents	A/prof Christine Rodda	Medicine
Effects of Vitamin D Status on Forearm Fracture Healing Rates in Children and Adolescents: A Pilot Study	A/Prof Christine Rodda	Medicine
Elizabeth Vincan	Professor Elizabeth Vincan	Infectious Diseases
Epidemiology and Public Health	Research Group Leader Professor Jodie McVernon	Infectious Diseases
Expression systems for pluripotent stem cells and their differentiated derivatives	Professor Ed Stanley	Paediatrics
Family Study of the Genetics of Autism Spectrum Disorder	Project Lead Professor Ingrid Scheffer	Medicine
Fertility preservation in children with cancer	Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Gene regulation in the developing retina and the childhood eye cancer retinoblastoma	Prof David Eisenstat	Paediatrics
Genetics Education and Health Research	Research Group Leader Professor Sylvia Metcalfe	Paediatrics
Genetics of childhood hearing loss	Dr Valerie Sung	Paediatrics
Healthy Mothers, Healthy Babies in Papua New Guinea – The impact of nutrition, malaria, and other infections on pregnant women and infants	Prof James Beeson	Medicine
High Dimensional Immune and Epigenetic Profiling of Children with Juvenile Idiopathic Arthritis (JIA)	Prof Richard Saffery	Paediatrics
Human resource capacity building for child health in Laos PDR	Project Leader Dr Amy Gray	Paediatrics
Identifying targets and mechanisms of acquired immunity to severe malaria in children	Prof James Beeson	Medicine
Identifying the genetic causes of brain malformation in children	A/Prof Paul Lockhart	Paediatrics
Immune mechanisms of peanut allergy remission	Prof Mimi Tang	Paediatrics
Immunoregulatory effects of Vitamin D supplementation on the development of allergy in the first year of life	Prof Richard Saffery	Paediatrics
Impact of Extreme Prematurity or Extreme Low Birthweight on Young Adult Health and Well-being	A/Prof Jeanie Cheong	Obstetrics and Gynaecology
Implementation considerations for a national program for expanded reproductive carrier screening	Dr Alison Archibald	Paediatrics
Improving lifetime outcomes for babies in special care nurseries	Prof Melissa Wake	Paediatrics
Inequities in children’s mental health: evidence to inform precision policy responses	Professor Sharon Goldfeld	Paediatrics
Infant and Family Wellbeing after Cardiac Surgery: Life as a Pre-schooler	PhD student Tamera Clancy	Paediatrics
Infectious Diseases Group	Research Group Leader Professor Nigel Curtis
Infertility in women and embryo implantation failure: identifying mechanistic insights using new genetic human technologies	Prof Eva Dimitriadis	Obstetrics and Gynaecology
Inflammatory mediators in the development of preeclampsia and pre-term birth.	Professor Eva Dimitriadis	Obstetrics and Gynaecology
Innate immune responses to Plasmodium falciparum infected erythrocytes	Group Leader Professor Stephen Rogerson	Medicine
International and Immigrant Health	Group Leader Professor Beverley-Ann Biggs	Medicine
Interplay between Streptococcus pneumoniae and respiratory viruses	A/Prof Catherine Satzke	Paediatrics
Intestinal Failure and Clinical Nutrition Group	Group Leader Professor Julie Bines	Paediatrics
Investigating metalloproteinases and their inhibitors in association with the short cervix and fetal fibronectin for the prediction of preterm labour in symptomatic women.	Project Leader Associate Professor Harry Georgiou	Obstetrics and Gynaecology
Investigating the molecular basis of parkinson's disease using novel genetic models	A/Prof Paul Lockhart	Paediatrics
Jodie McVernon	Professor Jodie McVernon	Infectious Diseases
Kidney Development, Disease and Regeneration	Research Group Leader Professor Melissa Little	Paediatrics
Kids In Communities Study (KiCS)	Project Lead Dr Karen Villanueva	Paediatrics
Linking determination of cell fate in the developing nervous system to paediatric brain tumours	Prof David Eisenstat	Paediatrics
Long-term impact of moderate and late preterm birth: effects on neurodevelopment, brain development and respiratory health at school age	Professor Jeanie Cheong	Paediatrics
Longitudinal and secular trends in outcomes for adolescents with hearing impairment in Victoria	Dr Valerie Sung	Paediatrics
Making B-lymphocytes form pluripotent stem cells	Professor Ed Stanley	Paediatrics
Malaria: Going bananas for sex	Dr Matthew Dixon	Infectious Diseases
Mapping hospital health records in Victoria, Australia for tracking pregnancy medicines use	Dr Yanhong Jessika Hu	Paediatrics
Maternal Fetal Medicine Pregnancy Research Centre	Director Prof Shaun Brennecke	Obstetrics and Gynaecology
Measuring developmental outcomes for Aboriginal and Torres Strait Islander children	Dr Anita d'Aprano	Paediatrics
Metabolic reprogramming of the failing heart	Dr Alejandro Hidalgo-Gonzalez	Paediatrics
Microbial changes following pneumococcal conjugate vaccination	A/Prof Catherine Satzke	Paediatrics
Modelling T-cell Development using pluripotent stem cells	Professor Ed Stanley	Paediatrics
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland	Obstetrics and Gynaecology
Molecular Oncology	Research Group Leader Professor Elizabeth Vincan	Infectious Diseases
Molecular remodelling of endothelial cells in response to specific lymphocytes and other signals	Prof Richard Saffery	Paediatrics
Nephrotoxicity screening using stem cell-derived proximal tubules	Prof Melissa Little	Paediatrics
Neuropsychological profile of children with childhood apraxia of speech	Professor Angela Morgan	Paediatrics
New vaccines group	Professor Kim Mulholland	Paediatrics
Newborn Health Project, Solomon Islands	Project Lead Professor Trevor Duke	Paediatrics
Newborn Research Centre	Head of Research Group Professor Peter Davis	Obstetrics and Gynaecology Research
Obstetrics, Nutrition and Endocrinology Group	Research Group Leader Associate Professor Martha Lappas	Obstetrics and Gynaecology
Optimising use of everyday technology for children and adolescents with acquired brain injury	Dr Sarah Knight	Paediatrics
Oral Health and Attitudes in Young Adults Aged 15-25 Years with Diabetes Mellitus: A Case - Control Study	A/Prof Christine Rodda	Medicine
Paediatric and Adolescent Fertility Preservation Taskforce	Senior Lecturer Yasmin Jayasinghe	Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Paediatric social work research group	Associate Professor Brigid Jordan	Paediatrics
Pain in children with cerebral palsy and other developmental disabilities	A/Professor Adrienne Harvey	Paediatrics
Pathogenesis and Immunity in Malaria	Research Group Leader Professor Stephen Rogerson	Infectious Diseases
Placental Cord Blood Cell Therapy in Children at High Risk of Heart Failure	A/Prof Salvatore Pepe	Paediatrics
Pneumococcal Research	Project Lead Professor Kim Mulholland	Paediatrics
Precision prediction of maternal and child outcomes from routine fetal ultrasounds	Prof Melissa Wake	Paediatrics
Predictors of infection, clinical severity and immunological legacy of SARS-CoV-2 in extant longitudinal LifeCourse population cohorts of children and their household/family contacts	Associate Professor Kirsten Perrett	Paediatrics
Prevention of nut allergies in high risk infants	A/Prof Kirsten Perrett	Paediatrics
Prognostic biomarkers of preterm labour. Development of a predictive test kit for preterm labour.	Associate Professor Harry Georgiou	Obstetrics and Gynaecology Research
Psychosocial determinants of health in infants & preschool children with Cystic Fibrosis diagnosed via newborn screening	Associate Professor Brigid Jordan	Paediatrics
R E Ross Trust Regional Child Health Fellowship Program	Project Leader Professor Trevor Duke	Paediatrics
Rare Diseases Now - Great care for rare	A/Prof Tiong Tan	Paediatrics
Regulating the vascularisation of the human glomerulus in vitro.	Prof Melissa Little	Paediatrics
Resolving inflammation in childhood respiratory disease	Dr Melanie Neeland	Paediatrics
Respiratory strategies to protect the preterm lung at birth	Dr Prue Pereira-Fantini	Paediatrics
Reverse translation to better understand fetal growth restriction	Associate Professor Tu'uhevaha Kaitu'u-Lino	Obstetrics and Gynaecology
Rogerson Laboratory: Pathogenesis of malaria and immunity in children and pregnant women	Group Leader Professor Stephen Rogerson	Medicine
Rotavirus Group and Enteric Virus Group	Group Leader Professor Julie Bines	Paediatrics
Savige Laboratory	Group Leader Professor Judy Savige	Medicine
Sexually transmitted infections and viral hepatitis	Research Group Leader Dr Simon Graham	Infectious Diseases
Simon Graham	Dr Simon Graham	Infectious Diseases
Stephen Rogerson	Professor Stephen Rogerson	Infectious Diseases
Stress Reactivity in Pre-schoolers with Congenital Heart Disease	Associate Professor Brigid Jordan	Paediatrics
Structural biology of proteins involved in infection	Dr Craig Morton	Medicine
Supporting young people with complex disability to participate in important life situations	Prof Christine Imms	Paediatrics
Taking placenta to scale: The population burden of disordered placentation and placental function	Prof Melissa Wake	Paediatrics
Targeting novel mediators of chronic pain to improve analgesia for Epidermolysis Bullosa	A/Prof Ken Pang	Paediatrics
The Collaborative AuTism Study (CATS)	Professor Ingrid Scheffer	Medicine
The development of feeding in infants with oesophageal atresia between birth and nine months of age	PhD student Libby Ferguson	Paediatrics
The long term outcomes of children of pregnancies complicated by diabetes	Dr Anthea Lindquist	Obstetrics and Gynaecology
The Renovators Dream: Malaria host cell remodelling	Dr Matthew Dixon	Infectious Diseases
Towards treatment of intellectual disability caused by errors in the chromatin machinery	Professor David Amor	Paediatrics
Trans Health Research	Dr Ada Cheung	Medicine
Tuning in to Kids emotion-focused interventions	Professor, Principal Researcher, Program Author Sophie Havighurst	Psychiatry
Understanding and defining supportive health/NDIS service environments	Prof Christine Imms	Paediatrics
Understanding pneumococcal pathogenesis	A/Prof Catherine Satzke	Paediatrics
Understanding the neurobiology of autism in NF1 using patient derived stem cell models	Dr Kiymet Bozaoglu	Paediatrics
Understanding the pathogenesis of gestational diabetes	Associate Professor Martha Lappas	Obstetrics and Gynaecology
Understanding what triggers birth? New opportunities for prevention of early delivery	Associate Professor Martha Lappas	Obstetrics and Gynaecology
Unravelling the Inflammatory Signatures of Paediatric Respiratory Disease	Dr Melanie Neeland	Paediatrics
Use of a respiratory function monitor to improve training efficiency in neonatal face mask ventilation	Dr MD PhD Marta Thio	Obstetrics and Gynaecology
Using biomarkers and ultrasound in late pregnancy to minimise preventable stillbirth: the BUMPS study	Head of Research Group Professor Sue Walker	Obstetrics and Gynaecology
Using parasite and vector serosurveillance to inform malaria elimination	Professor Freya Fowkes	Medicine
Utilizing technology to optimise ADHD care	Professor Dave Coghill	Paediatrics
Vitamin D supplementation for prevention of allergy in the first year of life	A/Prof Kirsten Perrett	Paediatrics
‘Find and Follow’: scoping the data capture, reporting and follow-up of (i) pregnancies complicated by congenital abnormalities, (ii) health and development among ‘high risk’ newborns	Head of Research Group Professor Sue Walker	Obstetrics and Gynaecology

140

Critical Care

Groups / Projects	Research Lead	Dept / Centre
7-SIGMA Study	Principal Investigator Dr Lachlan Miles	Critical Care
A parallel group, blinded, placebo controlled, ranDomised pRagmatic clinical trial investigating the Effect of temazepAM on objective and subjective measures of sleep in critically ill patients (The DREAM trial)	A/Prof Adam Deane	Medicine
Anaesthesia, Perioperative and Pain Medicine	Professor and Head, APPMU; Director, Melbourne Clinical and Translational Science Research Platform (MCATS) David Story	Critical Care
ASAP Study	Professor David Story	Critical Care
Asia Pacific Research Accelerator (APRA) Program