Clinical Trials Research Unit, Centre for Eye Research Australia

Research Overview

A/Prof Lyndell Lim, a Uveitis and Medical Retina Subspecialist, leads the Clinical Trials Research Unit at the Centre for Eye Research Australia. A/Prof Lim is largely involved in clinical studies, particularly in the field of uveitis and ocular immunology, and diabetic retinopathy. Her team runs both investigator initiated and sponsored clinical trials that aim to investigate new treatments in a variety of ophthalmic diseases.                                                                                                                                                                                                                                                                                                                           

Current projects include prospective randomised clinical trials in diabetic macular oedema, the major cause of visual loss in diabetic retinopathy, and chronic non-infectious uveitis, a form of blinding auto-immune disease of the eye.                                                                                                                                                                                                                                                                                                                           

Other Clinical Investigators within the Unit include Dr Sanjeewa Wickremasighe and Dr Suki Sandhu who are both Medical Retina Subspecialists. Their research focus is also in clinical ophthalmology in the fields of diabetic retinopathy and retinal vascular diseases.

Staff

Sanj Wickremasinghe, Clinical Investigator

Sukhi Sandhu, Clinical Investigator

Helen Ormandy, Clinical Trials Unit Manager

Kelly Mikunda, Executive Assistant

Carly Parfett, Senior Study Coordinator

Tanya Pejnovic, Senior Study Coordinator

Jessica Brennan, Study Coordinator

Roberta Cimetta, Research Assistant

Maria Kolic, Study Coorindator

Thuy Chau, Study Coordinator

Sutha Sanmugasundram, Study Coordinator

Marios Constantinou, Senior Study Coordinator

Julie Morrison, Senior Study Coordinator & Training Manager

Kiera Young, Study Coordinator

Theona Nicolau, Study Coordinator

Lauren Hodgson, Retinal Image Grading Centre Manager

Jessica Alessi-Calandro, Retinal Image Grader

Elizabeth Alesandrello, Retinal Image Grader

Collaborators

Professor Mark Gillies, Save Sight Institute/Sydney Eye Hospital, Sydney, NSW

A/Professor Samantha Fraser-Bell, Save Sight Institute/Sydney Eye Hospital, Sydney, NSW

Professor Peter McCluskey, Save Sight Institute/Sydney Eye Hospital, Sydney, NSW

Professor Doug Jabs, Mount Sinai Medical Center, New York, USA

Dr Nisha Acharaya, University of California San Francisco, California, USA

Dr James T Rosenbaum, Casey Eye Institute, Portland, Oregon, USA

Dr Friederike Mackensen, Heidelberg University, Heidelberg, Germany

Dr John Kempen, University of Pennsylvania, USA

Professor Ian Wicks, WEHI

A/Professor Anthony Hall, Alfred Hospital, Victoria

A/Professor Andrew Symons, Royal Melbourne Hospital, Victoria

Funding

NHMRC Early Career Fellowship

Sponsored Drug trials (Bayer, Allergan etc).

Research Opportunities

This research project is available to PhD students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Publications

1.Gillies MC, Lim LL, Campain A, Quin GJ, Salem W, Li J, Goodwin S, Aroney C, McAllister IL & Fraser-Bell S. A randomized clinical trial of intravitreal bevacizumab versus intravitreal dexamethasone for diabetic macular edema: the BEVORDEX study. Ophthalmology 2014;121(12):2473-81.

2.Suhler EB, Lim LL, Beardsley RM, Giles TR, Pasadhika S, Lee ST, de Saint Sardos A, Butler NJ, Smith JR & Rosenbaum JT. Rituximab Therapy for Refractory Scleritis: Results of a Phase I/II Dose-Ranging, Randomized, Clinical Trial. Ophthalmology 2014;121(10):1885-91.

3.Chiam NP, Hall AJ, Stawell RJ, Busiya L & Lim LL. The course of uveitis in pregnancy and postpartum. Br J Ophthalmol 2013;97:1284-1288.

4.Fenwick E, Lamoureux EL, Finger RP, Lim LL & Rees G. Patients’ causal beliefs about diabetic retinopathy. Optom Vis Sci. 2013; 90(8):874-882.

5.Fraser-Bell S, Lim LL, Campain A, Mehta H, Aroney C, Bryant J, Li J, Quin GJ, McAllister IL, Gillies MC. Bevacizumab or Dexamethasone Implants for DME: 2-year Results (The BEVORDEX Study). Ophthalmology 2016 Jan 9. [Epub ahead of print].

Research Projects

This Research Group doesn't currently have any projects



Faculty Research Themes

Infection and Immunology

School Research Themes

Neuroscience & Psychiatry



Key Contact

For further information about this research, please contact Associate Professor Lyndell Lim

Department / Centre

Surgery