Departmental Seminars

Every weekday, until 27th Nov 2017
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2017 Seminars - No RSVP required

Adolescent risk-taking in the Raine cohort
Dr Jennifer Marino
Department of Obstetrics & Gynaecology, The University of Melbourne
Monday 24 April, 12.30 pm, Seminar Rooms 7D/E, Level 7, The Royal Women’s Hospital

Adolescent Climbing

Adolescence is normally a time of exploring boundaries and seeking new experiences. However, health-related risk behaviour is responsible for the majority of adolescent morbidity and mortality worldwide. Externalising behaviour is “acting-out” behaviour linked to undercontrol and disinhibition, such as oppositional, antisocial, and attention deficit problems. Using the Western Australian Pregnancy Cohort (Raine) Study, we have explored relationships between childhood externalising behaviour and a range of health-related risk behaviours in adolescence.

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Gestational Diabetes: A health and economic outcome analysis
Dr Thomas Cade
Department of Obstetrics & Gynaecology, The University of Melbourne
Monday 01 May, 12.30 pm, Seminar Rooms 7A/B, Level 7, The Royal Women’s Hospital

Pregnant woman doing diabetes blood test Gestational diabetes has undergone a recent diagnostic change based on robust evidence from the HAPO trial subsequently endorsed by the World Health Organisation. This has been widely adopted in Australia and was introduced to the Royal Women's Hospital in 2015 but has not gained universal international acceptance. There has been an increase in yearly incidence by 85% with associated increases in workload and care package costs. We aim to examine the health outcomes of women and babies under the old and the new system with reference to each other and to appropriate non-diabetic control groups within the same years. We also plan an economic evaluation of this change.

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Vascular dysfunction in preeclampsia: an ex vivo approach to assess drugs
Sarah Marshall, Early Career Researcher
Monash University
Monday 08 May, 12.30 pm, Seminar Rooms 7D/E, Level 7, The Royal Women’s Hospital

Image of ex viv model of vascular dysfunctionA characteristic of preeclampsia (PE) is widespread maternal vascular dysfunction, often attributed to high circulating concentrations of anti-angiogenic factors sFlt-1 and sEng. In an attempt to replicate this dysfunction, an ex vivo model was established. Primary trophoblast cells were cultured for 24 hours to secrete large amounts of sFlt-1 and sEng, termed trophoblast conditioned media (TCM). Mouse arteries were exposed to TCM providing levels of sFlt-1 and sEng similar to those during PE to cause vascular dysfunction. This ex vivo model is now being utilized to assess the therapeutic ability of a variety of drugs to alleviate maternal systemic vascular dysfunction associated with PE.

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Normal tissue response to synchrotron microbeam radiotherapy
Jessica Ventura, PhD Student
Department of Obstetrics & Gynaecology, The University of Melbourne
Thursday 11 May, 10.30 am, Seminar Rooms 7A/B, Level 7, The Royal Women’s Hospital

Illustration of Australian Synchrotron

Microbeam Radiation therapy (MRT) is a novel pre-clinical synchrotron-based radiation therapy modality that shows promise in improving cancer control if successfully translated to human clinical trials. The main aims of this study are to generate data to determine the fundamental radiation biology of MRT and to inform clinical decision-making to obtain approval for human phase-1 toxicity trials. This talk will highlight data collected on biodosimetric-dose-equivalence approaches to evaluate the efficacy of MRT versus Broad Beam and CRT. A seperate but related line of investigation into the immune response and its role in the radiation induced bystander effects (RIBE) will also be discussed.

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TBA
Ramin Khanabdali, PhD Student
Department of Obstetrics & Gynaecology, The University of Melbourne
Monday 15 May, 12.30 pm, Seminar Rooms 7D/E, Level 7, The Royal Women’s Hospital

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The changing landscape of cervical cancer in the era of HPV vaccination
Dr Dorothy Machalek, Postdoctoral Research Fellow
Department of Microbiology & Infectious Diseases, The Royal Women’s Hospital
Monday 22 May, 12.30 pm, Seminar Rooms 7D/E, Level 7, The Royal Women’s Hospital

HPV Brochure Dorothy Machalek is an early career epidemiologist, specialising in human papillomavirus (HPV) prevention research. She is currently leading a Commonwealth Department of Health funded HPV vaccine evaluation program at the Royal Women’s Hospital. The program aims to track the prevalence of HPV infection, both vaccine and non-vaccine types over time, to make sure the National HPV Vaccination Program is doing what it is supposed to do in preventing infections. In her talk, Dorothy will review the epidemiology of HPV, including its role in cervical and other cancers, as well as the impact of HPV vaccination in Australia.

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TBA
Dr Quynh Nguyen, PhD Student
Department of Obstetrics & Gynaecology, The University of Melbourne
Monday 29 May, 12.30 pm, Seminar Rooms 7D/E, Level 7, The Royal Women’s Hospital

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Going Viral: Introduction to Media and Social Media
Krista Eleftheriou, Media Manager and Michelle Carnovale, Senior Media Advisor
Communications Department, The Royal Women's Hospital
Monday 26 June, 12.30 pm, Seminar Rooms 7A/B, Level 7, The Royal Women’s Hospital

7.30 Report film crew filming at RWH

This presentation explores what makes news, how the Women's can raise its profile, the opportunities to reach and engage a broader audience through social media and tips and pitfalls when engaging in media and social media.

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