Novel investigations and treatments for intractable, chronic constipation
The Surgical Research Group works on a number of surgical problems affecting children, including:
- Normal and abnormal descent of the testis, with the aim of understanding the mechanism and providing possible non-surgical treatment - Project Leader: John Hutson
- Normal and abnormal postnatal germ cell development, which is believed to be the key to preventing infertility and testicular cancer in men with previous undescended testes in childhood - Project Leader : Ruili Li
- The causes of intractable chronic constipation, and the development of novel investigations and novel treatments, including electrical stimulation - Project Leader: Bridget Southwell
- The cause of duodenal atresia, using a new knockout mouse with downregulation of FGF10 - Project Leader: Warwick Teague
- Novel treatments for colorectal disorders such as anorectal anomalies and Hirschsprung disease - Project Leader: Sebastian King
- Using state-of-the-art manometry to understand surgical problems in the gut, such as oesophageal atresia and Hirschsprung disease - Project Leader: Sebastian King
- Prof John Hutson - Chair of Paediatric Surgery/MCRI Hon Fellow
- A/Prof Warwick Teague - General Surgeon/MCRI Fellow
- Mr Sebastian King - General Surgeon/MCRI Fellow
- Dr Bridget Southwell - Group Leader Surgical Research Group MCRI
- Dr Ruili Li - Scientist, Surgical Research Group
- Dr Jaya Vikramen - PhD student
- Ms Julie Jordan-Ely, Master Student
- National Health & Medical Research Council
- Royal Children's Hospital Foundation
- Murdoch Children's Research Institute
- G-I Therapies
This research project is available to PhD, Masters, Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
- Nuclear transit study in children with chronic faecal soiling after Hirschsprung disease (HSCR) surgery has revealed a group with rapid proximal colonic treatment and possible adverse reactions to food.Stathopoulos L, King SK, Southwell BR, Hutson JM.Pediatr Surg Int. 2016 Aug;32(8):773-7
- Home Transcutaneous Electrical Stimulation Therapy to Treat Children With Anorectal Retention: A Pilot Study. Yik YI, Stathopoulos L, Hutson JM, Southwell BR. Neuromodulation. 2016 Jul;19(5):515-21
- The effect of food withdrawal in children with rapid-transit constipation.Kearsey I, Hutson JM, Southwell BR. Pediatr Surg Int. 2016 Jul;32(7):683-9.
- Disimpaction of children with severe constipation in 3-4 days in a suburban clinic using polyethylene glycol with electrolytes and sodium picosulphate. Jordan-Ely J, Hutson JM, Southwell BR. J Paediatr Child Health. 2015 Dec;51(12):1195-8
- Management of severe faecal impaction in an adolescent with Duchenne muscular dystrophy (DMD) receiving palliative care. Jordan-Ely J, Dobson KM, Appaduray S, Hynson J, Kornberg AJ, Hutson JM, Southwell BR.J Paediatr Child Health. 2015 Mar;51(3):351-2
- Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC).Hutson JM, Dughetti L, Stathopoulos L, Southwell BR. Pediatr Surg Int. 2015 May;31(5):445-51
- Potentially avoidable hospitalisation for constipation in Victoria, Australia in 2010-11. Ansari H, Ansari Z, Hutson JM, Southwell BR. BMC Gastroenterol. 2014 Jul 11;14:125.