Cancer in Medicine

Groups / Projects	Research Lead	Dept / Centre
A monoclonal antibody (mAb1F5) has been developed that identifies a unique marker, a membrane protein expressed by pericytes and meningeal cells	Dr Peter Wookey	Medicine
A mouse model of duodenal atresia	Project Leader Associate Professor Warrick Teague	Paediatrics
A New reagent for detection of program cell death	Dr Peter J Wookey	Medicine
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer		Medicine
A systematic review of end of life quality of care indicators	Prof Jennifer Philip	Medicine
A systematic review of the management of sleep in palliative care cancer patients	Prof Jennifer Philip	Medicine
A therapeutic strategy for killing cancer cells by DNA repair inhibition	A/Prof Andrew Deans	Medicine
A5 SDHB Genomics Study	Head of Laboratory Dr Richard Tothill	Clinical Pathology
ACRF Translational Research Laboratory	Group Leader Professor David S Ritchie	Medicine
Advanced Limb Reconstruction	Head of Department of Surgery, St. Vincent's Hospital, Professor Peter Choong	Surgery
An anti-calcitonin receptor (CTR) antibody for detection of programmed cell death: the role of CTR in a novel adaptive response to cell stress	Dr Peter Wookey	Medicine
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines.	Dr Peter J Wookey	Medicine
Brain Cancer Invasion Group	Dr Stanley Stylli	Surgery
Brain Cancer Microenvironment and Biology Laboratory	Dr Theo Mantamadiotis	Surgery
Brain Tumours and Epilepsy	Associate Professor Andrew Morokoff	Surgery
Breast Cancer	Head of Group Professor Bruce Mann Lead Researcher Dr Anita Skandarajah	Surgery
Buchanan laboratory: Oncogenomics (colorectal cancer)	Head of Laboratory Associate Professor Daniel Buchanan	Clinical Pathology
Coin Laboratory: Cancer Bioinformatics	Head of Laboratory Professor Lachlan Coin	Clinical Pathology
Cancer Biology Research Group	Professor Graham Baldwin	Surgery
Cancer drug discovery by inhibition of a DNA repair pathway with Crispr/Cas9 gene editing and biochemistry	Dr Wayne Crismani	Medicine
Cancer Immunotherapy symptoms: the experience and expectations around management	Program Trial Coordinator Leeanne Pasanen	Medicine
Cancer in Primary Care	Research Program Leader Professor Jon Emery	General Practice
Cancer Signaling Research Laboratory	Dr Hong-Jian Zhu	Surgery
Cardiovascular and Tumourivascular Laboratory	Dr Peter J Wookey Professor David Hare	Medicine
Care Plus Study	Research Assistant Roslyn Le Gautier	Medicine
Cellular and Molecular Mechanisms Driving Anthracycline-Induced Cardiotoxicity in Children	Dr Alexander Pinto	Baker Department of Cardiometabolic Health
Cellular and Molecular Mechanisms Driving Anthracycline-Induced Cardiotoxicity in Children	Dr Alexander Pinto	Baker Department of Cardiometabolic Health
Centre for research excellence in cervical cancer control		Obstetrics and Gynaecology Research
Characterisation of complex structural variation in bacterial and human genomes	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Characterising Respiratory Infections in Immune-suppressed Haematology and Transplant Patients	Professor Monica Slavin	Medicine
CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Circulating Biomarkers in Liver Malignancy	Professor Christopher Christophi	Surgery
CRISP-DNA: The feasibility of assessing bowel cancer risk using genomic testing to target screening in general practice	Herman Professor of Primary Care Cancer Research Professor Jon Emery	General Practice
Defining new biomarkers and therapeutic targets in heart failure	Associate Professor Morag Young	Baker Department of Cardiometabolic Health
Defining the Role of Transcriptional Stress Pathways in Cancer Cell Resistance Towards Anti-Cancer Therapeutics	A/prof John Price	Medicine
Developing clinical genomic methods for cancer of unknown primary	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Development and validation of triage guidelines for colonoscopy and gastroscopy		General Practice
Elizabeth Vincan	Professor Elizabeth Vincan	Infectious Diseases
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit	Research Group Leader Dr Michelle Peate	Obstetrics and Gynaecology
Endocrine Surgery	Associate Professor Julie Miller	Surgery
Enhance: A multi-centre, randomised phase IV study		Medicine
Enteric Neuropathy as a Target to Alleviate Gastrointestinal Side-effects of Chemotherapy	A/prof Kulmira Nurgali	Medicine
Establishing patterns of primary health care usage in cancer at the end of life	Matthew Grant	Medicine
Evaluating molecular biomarkers of anal cancer risk		Obstetrics and Gynaecology
Fertility After Cancer Predictor (FoRECAsT) Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Fertility decision tools for young women with breast cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer	Senior Lecturer Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Fertility preservation in children with cancer	Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Finding a needle in the haystack: ctDNA detection for tracking cancer evolution and refining cancer risk	Associate Professor Daniel Buchanan	Clinical Pathology
Function and cryo-EM structure of the breast cancer predisposition gene BRCA1	A/Prof Andrew Deans	Medicine
Gene regulation in the developing retina and the childhood eye cancer retinoblastoma	Prof David Eisenstat	Paediatrics
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Glioblastoma Survival Signaling Lab	Dr Rodney Luwor	Surgery
Gynaecology Research Centre - Hickey Group	Research Group Leader Professor Martha Hickey	Obstetrics and Gynaecology
Head and Neck Tumour Stream Research Group	Professor David Wiesenfeld	Surgery
Heterogeneity of treatment response in advanced cancer: role of intrinsic and microenvironmental factors	AProfessor Frederic Hollande	Clinical Pathology
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer	Head of Laboratory Professor Fred Hollande	Clinical Pathology
Honorary Appointments’ Research Projects		Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance	Professor Christopher Christophi	Surgery
Identification and Characterisation of Molecular Mediators of Cancer Metastasis	A/prof John Price	Medicine
Identifying and characterising Lynch syndrome within the population	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying better therapies for patients with myelodysplastic syndromes.	Professor Louise Purton	Medicine
Identifying biomarkers of risk and poor prognosis in CRC	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Improving reproductive health through infectious diseases research		Obstetrics and Gynaecology
Inflammation-induced Cancer: Mechanisms and Novel Treatments	A/prof Kulmira Nurgali	Medicine
Informal Communities in Cancer Treatment	Project Lead Dr Matt Grant	Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David Ritchie	Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David S Ritchie	Medicine
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer	Group Leader, acting Head of Department Associate Professor Fred Hollande	Clinical Pathology
Investigating the link between phenotype change and treatment resistance in prostate cancer	Associate Professor Niall Corcoran	Surgery
Linking determination of cell fate in the developing nervous system to paediatric brain tumours	Prof David Eisenstat	Paediatrics
Liver Group	Professor Christopher Christophi	Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Project Lead Dr Rachel Koldej	Medicine
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Prof David Ritchie	Medicine
Manometric studies on oesophageal atresia and colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
Mesenchymal Stem Cell-based Therapies for Inflammatory Bowel Disease and Colorectal Cancer	A/prof Kulmira Nurgali	Medicine
Metastasis Research Group	Professor Albert G Frauman	Medicine
Molecular Mechanisms of Tumour Resistance Laboratory	Dr Rodney Luwor	Surgery
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland	Obstetrics and Gynaecology
Neurosurgery	Professor Kate Drummond	Surgery
NHMRC Centre for Research Excellence for Reducing the Burden of Colorectal Cancer by Optimising Screening	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Novel Approaches in Therapeutic Endoscopy	A/prof Alan Moss	Medicine
Novel genetic interactions with the double-stranded RNA-induced autoimmunity pathways	A/Prof Carl Walkley	Medicine
Novel investigations and treatments for intractable, chronic constipation	Project Leader Dr Bridget Southwell	Paediatrics
Novel treatments for colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
OPPtiC: A pilot feasibility study of establishing a clinical opioid pharmacogenomics database in palliative care	Program Trial Coordinator Leeanne Pasanen	Medicine
Optimising the management of patients awaiting liver transplantation	Professor Christopher Christophi Senior Lecturer Michael Fink	Surgery
PaCCSC RAPID Series - Cancer-related Lymphoedema	Beth Russell	Medicine
Paediatric and Adolescent Fertility Preservation Taskforce	A/Prof Yasmin Jayasinghe	Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Jennifer Philip	Group Leader Professor Jennifer Philip	Medicine
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility	Project Leader Dr Ruili Li	Paediatrics
Prevalence of Risk Factors for Melanoma in Primary Care Patients using the MelaTools Risk Calculator	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research,	General Practice
Priorities and Needs of Women Living with Advanced Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Probiotic therapy		Obstetrics and Gynaecology
Promoting and advancing midlife health in women	Project Leader Professor Martha Hickey	Obstetrics and Gynaecology
Prostate Cancer	Head of Group Professor Christopher Hovens Deputy Laboratory Head Associate Professor Niall Corcoran	Surgery
Prostate cancer progression inhibition	Group Leader Professor Albert G Frauman	Medicine
Prostate Cancer Research Group	Professor Christopher Hovens	Surgery
RAPID Postmarketing Study - Medicinal Cannabis		Medicine
Rare Disease Oncogenomics	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Professor David Ritchie	Medicine
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Group Leader Professor David Ritchie	Medicine
Reducing disparities in mortality and survival for rural Victorians with colorectal cancer	Rebecca Bergin	General Practice
Regulation of blood cell production by endothelial cell-derived retinoic acid receptor gamma	Professor Louise Purton	Medicine
Regulation of cancer stem cell self-renewal in colorectal cancer	Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande	Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion	Dr Stanley Stylli	Surgery
Renal supportive care of patients with advanced chronic kidney disease	Kathryn Ducharlet	Medicine
Reproductive Steroids Research Group	Professor Mathis Grossmann, MD, PhD, FRACP	Medicine
The role of the essential biometal zinc in pathological and physiological processes	Professor Graham Baldwin Dr Oneel Patel Dr Joseph Ischia	Surgery
Role of p-21-activated kinases in pancreactic cancer	Professor Graham Baldwin Dr Mehrdad Nikfarjam	Surgery
Role of the Nervous System in Cancer Development and Progression	A/prof Kulmira Nurgali	Medicine
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection	Professor Christopher Christophi	Surgery
Serum biomarkers of brain cancer	Dr Andrew Morokoff	Surgery
Sex and the broken heart: sex-specific mechanisms driving heart failure	Dr Alexander Pinto	Baker Department of Cardiometabolic Health
Spinal Biology Laboratory	Doctor Gerald Quan	Surgery
STEP Care Clinical Trial	Project Lead Anna Collins	Medicine
Structural biology of proteins involved in cancer	Dr Craig Morton	Medicine
Studying the Continuum of Cancer Care through Linking Primary Data	Research Project Leader Professor Jon Emery	General Practice
Supporting earlier cancer diagnosis and efficient referral pathways in general practice		General Practice
Surgical Research Group	Chair of Paediatric Surgery Professor John M Hutson AO	Paediatrics
Fully Funded. Systematic EndoscopIc Staging of Mediastinum to determine Impact on radiotherapy for locally advanced lung Cancer (SEISMIC): an international multi-centre cohort study	Associate Professor Daniel Steinfort	Medicine
T cell function as a determinant of blinatumomab efficacy in B-ALL	Group Leader Professor David Ritchie	Medicine
Targeting the angiogenic and osteoclastic pathways in spinal cancer	Doctor Gerald Quan Doctor Gerald Quan	Surgery
Targeting the Lymphatics in colorectal Liver metastasis	Professor Christopher Christophi	Surgery
The application of a patient centred service design approach to improve patients experience of breast cancer care	Professor Christobel Saunders
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production	Professor Michael McCullough	Surgery
The CGA-Oncology Study: Comprehensive geriatric assessment and intervention in older lung cancer patients	Project Lead Professor Andrea B Maier	Medicine
The characterisation of CT Receptor expression in the CNS and perinatal PNS: the distribution, intracellular associations and functions of isoforms.	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer	Dr Peter J Wookey	Medicine
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer.	Dr Peter J Wookey	Medicine
The Genomic Drivers of High Risk Prostate cancer	Professor Christopher Hovens	Surgery
The impact of cancer therapies on the bone marrow microenvironment	Professor Louise Purton	Medicine
The role of EGFR Signaling in Glioblastoma Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The role of FANCM gene in inherited breast cancer	A/Prof Andrew Deans	Medicine
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of miRNA in oral mucosal disorders	Professor Michael McCullough	Surgery
The role of RECQL4 gene in cancer predispositon	Dr Andrew Deans	Medicine
The role of RNA editing enzyme ADAR1 in liver homeostasis and metabolism	A/Prof Carl Walkley	Medicine
The role of STAT3-mediated Cancer Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The treatment of the brain tumour glioblastoma (GBM): the efficacy of immunotoxin derived from anti-calcitonin receptor antibodies	Dr Peter J Wookey	Medicine
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Prof David Ritchie	Medicine
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Professor David S Ritchie	Medicine
Understanding the aetiology of Serrated Polyposis Syndrome	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma	Surgeon, Project Leader Dr David Gyorki	Surgery
Understanding the microenvironment of lymphodema	Dr Ramin Shayan	Surgery
Understanding the role of CXCR7 in lymphodema following radiation injury	Dr Ramin Shayan	Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism	Project Leader Professor John M Hutson AO	Paediatrics
Unravelling the causes of persistent exercise intolerance in cancer survivors	Dr Steve Foulkes	Baker Department of Cardiometabolic Health
Use of Connexin43 peptides as a treatment for glioma	Dr Stanley Stylli	Surgery
VCCC Building Capability in Clinical Trials Program	Program Trial Coordinator Leeanne Pasanen	Medicine
Western Health Cancer Research	Group Leader Professor Michael Green	Medicine
WomenCAN: Promoting and advancing women’s health and wellbeing after cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study.	Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey	Obstetrics and Gynaecology

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