Cancer in Medicine

Groups / Projects	Research Lead	Dept / Centre
A mouse model of duodenal atresia	Project Leader Associate Professor Warrick Teague
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer
A5 SDHB Genomics Study	Head of Laboratory Dr Richard Tothill
Aboriginal and Torres Strait Islanders	Chair of Palliative Medicine Prof Jennifer Philip
ACRF Translational Research Laboratory	Group Leader Professor David S Ritchie
Advanced Limb Reconstruction	Head of Department of Surgery, St. Vincent's Hospital, Professor Peter Choong
Brain Cancer Invasion Group	Dr Stanley Stylli
Brain Cancer Microenvironment and Biology Laboratory	Dr Theo Mantamadiotis
Brain Tumours and Epilepsy	Associate Professor Andrew Morokoff
Breast Cancer	Head of Group Professor Bruce Mann Lead Researcher Dr Anita Skandarajah
Buchanan laboratory: Oncogenomics (colorectal cancer)	Head of Laboratory Associate Professor Daniel Buchanan
CANARY (CANcer risk in patients with unexpected weight loss in primaRY care) Studies: Clinical Decision Support Systems for Cancer Prevention and Early Cancer Detection in Primary Care	Chief Investigator Dr. Javiera Martinez Gutierrez,
Coin Laboratory: Cancer Bioinformatics	Head of Laboratory Professor Lachlan Coin
Cancer Biology Research Group	Professor Graham Baldwin
Cancer Immunotherapy symptoms: the experience and expectations around management	Program Trial Coordinator Leeanne Pasanen
Cancer Signaling Research Laboratory	Dr Hong-Jian Zhu
Centre for research excellence in cervical cancer control
Characterisation of complex structural variation in bacterial and human genomes	Group Lead, Cancer Bioinformatics Professor Lachlan Coin
Circulating Biomarkers in Liver Malignancy	Professor Christopher Christophi
Clinical Trials
Completed Projects
Cost of Caregiving Study
Developing clinical genomic methods for cancer of unknown primary	Head of Laboratory Dr Richard Tothill
Elizabeth Vincan	Professor Elizabeth Vincan
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit	Research Group Leader A/Prof Michelle Peate
Endocrine Surgery	Associate Professor Julie Miller
Enhance: A multi-centre, randomised phase IV study
Establishing patterns of primary health care usage in cancer at the end of life	Matthew Grant
Evaluating molecular biomarkers of anal cancer risk
Fertility After Cancer Predictor (FoRECAsT) Study	Project Lead A/Prof Michelle Peate
Fertility preservation in children and teenagers with cancer	Senior Lecturer Dr Yasmin Jayasinghe
Fertility Preservation Taskforce	A/Prof Yasmin Jayasinghe
Future Health Today: A randomised control trial of pharmacological therapies to reduce cardiovascular risk in people with chronic kidney disease and investigation of people at increased risk of cancer	Study Coordinator Ms. Sophia Chima,
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA	Group Lead, Cancer Bioinformatics Professor Lachlan Coin
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers	Group Lead, Cancer Bioinformatics Professor Lachlan Coin
Glioblastoma Survival Signaling Lab	Dr Rodney Luwor
Gynaecology Research Centre - Hickey Group	Research Group Leader Professor Martha Hickey
Head and Neck Tumour Stream Research Group	Professor David Wiesenfeld
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer	Head of Laboratory Professor Fred Hollande
Honorary Appointments’ Research Projects
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance	Professor Christopher Christophi
How many women experience long-term side-effects after cancer and cancer treatment?	Project Lead A/Prof Michelle Peate
Human Liver Organoids	Project Lead Professor Kumar Visvanathan	St Vincent's Hospital
IC3 Trial: A Randomised Control Trial aiming to improve early diagnosis of liver cancer and improving patient health outcomes	IC3 National Manager Dr. Deborah De Guingand,
Identifying and characterising Lynch syndrome within the population	Head of Laboratory Dr Daniel Buchanan
Identifying biomarkers of risk and poor prognosis in CRC	Head of Laboratory Dr Daniel Buchanan
Identifying novel genetic risk factors for colorectal cancer	Head of Laboratory Dr Daniel Buchanan
Improving reproductive health through infectious diseases research
Improving the management of menopause symptoms in cancer survivorship	Project Lead A/Prof Michelle Peate
Informal Communities in Cancer Treatment	Project Lead Dr Matt Grant
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David S Ritchie
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer	Group Leader, acting Head of Department Associate Professor Fred Hollande
Liver Group	Professor Christopher Christophi
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer	Project Lead A/Prof Michelle Peate
MAGPIE Study: A genomic test intervention designed to provide patients with personalised melanoma, bowel, breast, and prostate cancer screening information	Study Coordinator Dr. Sibel Saya,
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Project Lead Dr Rachel Koldej
Manometric studies on oesophageal atresia and colorectal disorders	Project Leader Dr Sebastian King
Molecular Mechanisms of Tumour Resistance Laboratory	Dr Rodney Luwor
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland
National Pancreatic Cancer Roadmap Early Implementation Priorities
Neurosurgery	Professor Kate Drummond
Novel investigations and treatments for intractable, chronic constipation	Project Leader Dr Bridget Southwell
Novel treatments for colorectal disorders	Project Leader Dr Sebastian King
Opioid Pharmacogenomics	Palliative Medicine Physician and Medical Oncologist Dr Aaron K Wong
Optimising the management of patients awaiting liver transplantation	Professor Christopher Christophi Senior Lecturer Michael Fink
PaCCSC RAPID Series - Cancer-related Lymphoedema	Beth Russell
Paediatric Fertility Decision Aid Study	Project Lead A/Prof Michelle Peate
Jennifer Philip	Group Leader Professor Jennifer Philip
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility	Project Leader Dr Ruili Li
PRESIDE Trial: A Randomised Controlled Trial providing antidepressant medication information to patients with mild-to-severe depressive symptoms.	Trial Coordinator Dr Sibel Saya,
Priorities and Needs of Women Living with Advanced Cancer	Project Lead Dr Michelle Peate
Probiotic therapy
Promoting and advancing midlife health in women	Project Leader Professor Martha Hickey
Prostate Cancer	Head of Group Professor Christopher Hovens Deputy Laboratory Head Associate Professor Niall Corcoran
Prostate Cancer Research Group	Professor Christopher Hovens
RAPID Postmarketing Study - Medicinal Cannabis
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Group Leader Professor David Ritchie
Regulation of cancer stem cell self-renewal in colorectal cancer	Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande
Regulation of invadopodium function and involvement in cancer cell invasion	Dr Stanley Stylli
Renal supportive care of patients with advanced chronic kidney disease	Kathryn Ducharlet
Reproductive Steroids Research Group	Professor Mathis Grossmann, MD, PhD, FRACP
Revitalise Program
RoBiN (Risk of Breast Neoplasia): An acceptability and feasibility study of personalised screening	Lead Researcher Dr. Dulashi (Anna) Withanage Dona
The role of the essential biometal zinc in pathological and physiological processes	Professor Graham Baldwin Dr Oneel Patel Dr Joseph Ischia
Role of p-21-activated kinases in pancreactic cancer	Professor Graham Baldwin Dr Mehrdad Nikfarjam
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection	Professor Christopher Christophi
ROSELLA Study: Implementation of risk-stratified population screening for Australia’s most common cancers	Research Lead Dr. Sibel Saya,
SCRIPT Trial: A Randomised Controlled Trial utilising a genomic test as an intervention providing personalised bowel cancer screening information	Trial Coordinator Dr. Sibel Saya,
Serum biomarkers of brain cancer	Dr Andrew Morokoff
SMARTERScreen: A Randomised Controlled Trial based on evidence from SMARTScreen utilising SMS messages to prompt patients overdue with bowel cancer screening	Trial Coordinator Ms Anna Wood,
Spinal Biology Laboratory	Doctor Gerald Quan
STEP Care Clinical Trial	Project Lead Anna Collins
Surgical Research Group	Chair of Paediatric Surgery Professor John M Hutson AO
Sushama Telwatte	Locarnini Fellow in Virology Dr. Sushama Telwatte
T cell function as a determinant of blinatumomab efficacy in B-ALL	Group Leader Professor David Ritchie
Targeting the angiogenic and osteoclastic pathways in spinal cancer	Doctor Gerald Quan Doctor Gerald Quan
Targeting the Lymphatics in colorectal Liver metastasis	Professor Christopher Christophi
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production	Professor Michael McCullough
The Care Plus Study
The Care Plus Study
The CASSOWARY Trial: A Randomised Controlled Trial of the clinical utility and cost-effectiveness of a multi-cancer polygenic risk score in general practice	Research Fellow Dr. Sibel Saya,
The COMET Program
The IDEAL Care Trial: IDEntifying Advanced Liver Fibrosis in Primary Care	National Trial Coordinator Ms Eliza Smislja
The Partner Study
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli
The role of miRNA in oral mucosal disorders	Professor Michael McCullough
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Professor David S Ritchie
Understanding the aetiology of Serrated Polyposis Syndrome	Head of Laboratory Dr Daniel Buchanan
Understanding The Immune Environment in Metastatic Melanoma	Surgeon, Project Leader Dr David Gyorki
Undescended testis and inguinal hernia result from defects in the same mechanism	Project Leader Professor John M Hutson AO
Use of Connexin43 peptides as a treatment for glioma	Dr Stanley Stylli
Voices for Palliative Care
Western Health Cancer Research	Group Leader Dr Dishan Herath
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study.	Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey

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