Cancer in Medicine

Groups / Projects	Research Lead	Dept / Centre
A mouse model of duodenal atresia	Project Leader Associate Professor Warrick Teague	Paediatrics
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer		Medicine
A5 SDHB Genomics Study	Head of Laboratory Dr Richard Tothill	Clinical Pathology
ACRF Translational Research Laboratory	Group Leader Professor David S Ritchie	Medicine
Advanced Limb Reconstruction	Head of Department of Surgery, St. Vincent's Hospital, Professor Peter Choong	Surgery
Brain Cancer Invasion Group	Dr Stanley Stylli	Surgery
Brain Cancer Microenvironment and Biology Laboratory	Dr Theo Mantamadiotis	Surgery
Brain Tumours and Epilepsy	Associate Professor Andrew Morokoff	Surgery
Breast Cancer	Head of Group Professor Bruce Mann Lead Researcher Dr Anita Skandarajah	Surgery
Buchanan laboratory: Oncogenomics (colorectal cancer)	Head of Laboratory Associate Professor Daniel Buchanan	Clinical Pathology
CANARY (CANcer risk in patients with unexpected weight loss in primaRY care) Studies: Clinical Decision Support Systems for Cancer Prevention and Early Cancer Detection in Primary Care	Chief Investigator Dr. Javiera Martinez Gutierrez,	General Practice
Coin Laboratory: Cancer Bioinformatics	Head of Laboratory Professor Lachlan Coin	Clinical Pathology
Cancer Biology Research Group	Professor Graham Baldwin	Surgery
Cancer Immunotherapy symptoms: the experience and expectations around management	Program Trial Coordinator Leeanne Pasanen	Medicine
Cancer in Primary Care		General Practice
Cancer Signaling Research Laboratory	Dr Hong-Jian Zhu	Surgery
Care Plus Study	Research Assistant Roslyn Le Gautier	Medicine
Centre for research excellence in cervical cancer control		Obstetrics and Gynaecology Research
Characterisation of complex structural variation in bacterial and human genomes	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Circulating Biomarkers in Liver Malignancy	Professor Christopher Christophi	Surgery
Developing clinical genomic methods for cancer of unknown primary	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Elizabeth Vincan	Professor Elizabeth Vincan	Infectious Diseases
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit	Research Group Leader Dr Michelle Peate	Obstetrics and Gynaecology
Endocrine Surgery	Associate Professor Julie Miller	Surgery
Enhance: A multi-centre, randomised phase IV study		Medicine
Establishing patterns of primary health care usage in cancer at the end of life	Matthew Grant	Medicine
Evaluating molecular biomarkers of anal cancer risk		Obstetrics and Gynaecology
Fertility After Cancer Predictor (FoRECAsT) Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer	Senior Lecturer Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Future Health Today: A randomised control trial of pharmacological therapies to reduce cardiovascular risk in people with chronic kidney disease and investigation of people at increased risk of cancer	Study Coordinator Ms. Sophia Chima,	General Practice
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Glioblastoma Survival Signaling Lab	Dr Rodney Luwor	Surgery
Gynaecology Research Centre - Hickey Group	Research Group Leader Professor Martha Hickey	Obstetrics and Gynaecology
Head and Neck Tumour Stream Research Group	Professor David Wiesenfeld	Surgery
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer	Head of Laboratory Professor Fred Hollande	Clinical Pathology
Honorary Appointments’ Research Projects		Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance	Professor Christopher Christophi	Surgery
Human Liver Organoids	Project Lead Professor Kumar Visvanathan	Medicine
IC3 Trial: A Randomised Control Trial aiming to improve early diagnosis of liver cancer and improving patient health outcomes	IC3 National Manager Dr. Deborah De Guingand,	General Practice
Identifying and characterising Lynch syndrome within the population	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying biomarkers of risk and poor prognosis in CRC	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Improving reproductive health through infectious diseases research		Obstetrics and Gynaecology
Informal Communities in Cancer Treatment	Project Lead Dr Matt Grant	Medicine
Integrative genomics and immunobiology in Hairy Cell Leukaemia	Professor David S Ritchie	Medicine
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer	Group Leader, acting Head of Department Associate Professor Fred Hollande	Clinical Pathology
Liver Group	Professor Christopher Christophi	Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
MAGPIE Study: A genomic test intervention designed to provide patients with personalised melanoma, bowel, breast, and prostate cancer screening information	Study Coordinator Dr. Sibel Saya,	General Practice
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Project Lead Dr Rachel Koldej	Medicine
Manometric studies on oesophageal atresia and colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
Molecular Mechanisms of Tumour Resistance Laboratory	Dr Rodney Luwor	Surgery
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland	Obstetrics and Gynaecology
Neurosurgery	Professor Kate Drummond	Surgery
Novel investigations and treatments for intractable, chronic constipation	Project Leader Dr Bridget Southwell	Paediatrics
Novel treatments for colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
OPPtiC: A pilot feasibility study of establishing a clinical opioid pharmacogenomics database in palliative care	Program Trial Coordinator Leeanne Pasanen	Medicine
Optimising the management of patients awaiting liver transplantation	Professor Christopher Christophi Senior Lecturer Michael Fink	Surgery
PaCCSC RAPID Series - Cancer-related Lymphoedema	Beth Russell	Medicine
Paediatric and Adolescent Fertility Preservation Taskforce	A/Prof Yasmin Jayasinghe	Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Jennifer Philip	Group Leader Professor Jennifer Philip	Medicine
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility	Project Leader Dr Ruili Li	Paediatrics
PRESIDE Trial: A Randomised Controlled Trial providing antidepressant medication information to patients with mild-to-severe depressive symptoms.	Trial Coordinator Dr Sibel Saya,	General Practice
Priorities and Needs of Women Living with Advanced Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Probiotic therapy		Obstetrics and Gynaecology
Promoting and advancing midlife health in women	Project Leader Professor Martha Hickey	Obstetrics and Gynaecology
Prostate Cancer	Head of Group Professor Christopher Hovens Deputy Laboratory Head Associate Professor Niall Corcoran	Surgery
Prostate Cancer Research Group	Professor Christopher Hovens	Surgery
RAPID Postmarketing Study - Medicinal Cannabis		Medicine
Rare Disease Oncogenomics	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Recipient immunity as a determinant of long term outcome in bone marrow transplantation	Group Leader Professor David Ritchie	Medicine
Regulation of cancer stem cell self-renewal in colorectal cancer	Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande	Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion	Dr Stanley Stylli	Surgery
Renal supportive care of patients with advanced chronic kidney disease	Kathryn Ducharlet	Medicine
Reproductive Steroids Research Group	Professor Mathis Grossmann, MD, PhD, FRACP	Medicine
The role of the essential biometal zinc in pathological and physiological processes	Professor Graham Baldwin Dr Oneel Patel Dr Joseph Ischia	Surgery
Role of p-21-activated kinases in pancreactic cancer	Professor Graham Baldwin Dr Mehrdad Nikfarjam	Surgery
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection	Professor Christopher Christophi	Surgery
SCRIPT Trial: A Randomised Controlled Trial utilising a genomic test as an intervention providing personalised bowel cancer screening information	Trial Coordinator Dr. Sibel Saya,	General Practice
Serum biomarkers of brain cancer	Dr Andrew Morokoff	Surgery
SMARTERScreen: A Randomised Controlled Trial based on evidence from SMARTScreen utilising SMS messages to prompt patients overdue with bowel cancer screening	Trial Coordinator Ms Anna Wood,	General Practice
SMARTScreen: Utilisation of an SMS intervention with evocative videos sent to GP patients who are overdue in their bowel cancer screening	Project Leader A/Prof Jennifer McIntosh,	General Practice
Spinal Biology Laboratory	Doctor Gerald Quan	Surgery
STEP Care Clinical Trial	Project Lead Anna Collins	Medicine
Surgical Research Group	Chair of Paediatric Surgery Professor John M Hutson AO	Paediatrics
T cell function as a determinant of blinatumomab efficacy in B-ALL	Group Leader Professor David Ritchie	Medicine
Targeting the angiogenic and osteoclastic pathways in spinal cancer	Doctor Gerald Quan Doctor Gerald Quan	Surgery
Targeting the Lymphatics in colorectal Liver metastasis	Professor Christopher Christophi	Surgery
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production	Professor Michael McCullough	Surgery
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of miRNA in oral mucosal disorders	Professor Michael McCullough	Surgery
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Professor David S Ritchie	Medicine
Understanding the aetiology of Serrated Polyposis Syndrome	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma	Surgeon, Project Leader Dr David Gyorki	Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism	Project Leader Professor John M Hutson AO	Paediatrics
Use of Connexin43 peptides as a treatment for glioma	Dr Stanley Stylli	Surgery
VCCC Building Capability in Clinical Trials Program	Program Trial Coordinator Leeanne Pasanen	Medicine
Western Health Cancer Research	Group Leader Professor Michael Green	Medicine
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study.	Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey	Obstetrics and Gynaecology

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