Cancer in Medicine

Cancer in all its forms, encompasses research, prevention, detection, treatment, care and health system transformation to address this most significant burden of disease.

Groups / Projects Research Lead Dept / Centre
A mouse model of duodenal atresia Project Leader Associate Professor Warrick Teague Paediatrics
A5 SDHB Genomics Study Head of Laboratory Dr Richard Tothill Clinical Pathology
Academic Department of Surgery, Western Health Associate Professor Justin Yeung
Surgery
ACRF Translational Research Laboratory Group Leader Professor David S Ritchie
Medicine and Radiology
Advanced Limb Reconstruction Head of Department of Surgery,
St. Vincent's Hospital,
Professor Peter Choong

Surgery
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines. Dr Peter J Wookley Medicine and Radiology
Analysis of circulating microRNAs in patient serum as a non-invasive biomarker platform Project Lead Dr Rachel Koldej Medicine and Radiology
Boussioutas Laboratory: Gastrointestinal Cancer Group Leader Associate Professor Alex Boussioutas
Medicine and Radiology
Buchanan laboratory: Oncogenomics (colorectal cancer) Head of Laboratory Associate Professor Daniel Buchanan
Clinical Pathology
Cancer Biology Research Group Professor Graham Baldwin
Surgery
Cancer drug discovery by inhibition of a DNA repair pathway with Crispr/Cas9 gene editing and biochemistry Dr Wayne Crismani Medicine and Radiology
Cancer in Primary Care Research Group Leader Professor Jon Emery
General Practice
Cancer Signalling Research Laboratory Dr Hong-Jian Zhu
Surgery
Cardiovascular and Tumourivascular Laboratory Dr Peter J Wookey
Professor David Hare
Medicine and Radiology
Characterising Respiratory Infections in Immune-suppressed Haematology and Transplant Patients Professor Monica Slavin Medicine and Radiology
CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research
General Practice
Circulating Biomarkers in Liver Malignancy Professor Christopher Christophi Surgery
CRISP-DNA: The feasibility of assessing bowel cancer risk using genomic testing to target screening in general practice Herman Professor of Primary Care Cancer Research Professor Jon Emery General Practice
Developing clinical genomic methods for cancer of unknown primary Head of Laboratory Dr Richard Tothill Clinical Pathology
Developing interactome (Protein binding maps) maps for BRCA1 and the collagen I molecule affected in osteogenesis imperfecta Prof Judy Savige Medicine and Radiology
Development and validation of triage guidelines for colonoscopy and gastroscopy General Practice
Development of new treatments to halt the spread of endometrial cancer. Professor Eva Dimitriadis Obstetrics and Gynaecology
Fertility After Cancer Predictor (FoRECAsT) Study Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Fertility decision tools for young women with breast cancer Dr Michelle Peate Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer Senior Lecturer Dr Yasmin Jayasinghe Obstetrics and Gynaecology
Fertility preservation in children with cancer Dr Yasmin Jayasinghe Obstetrics and Gynaecology
Finding a needle in the haystack: ctDNA detection for tracking cancer evolution and refining cancer risk Associate Professor Daniel Buchanan Clinical Pathology
Function and cryo-EM structure of the breast cancer predisposition gene BRCA1 A/Prof Andrew Deans Medicine and Radiology
Gynaecology Research Centre Professor Women's Health Research Professor Peter Rogers
Obstetrics and Gynaecology
Harnessing novel immunotherapies to restore immunity in chronic lymphocytic leukaemia Group Leader Professor David Ritchie Medicine and Radiology
Heterogeneity of treatment response in advanced cancer: role of intrinsic and microenvironmental factors AProfessor Frederic Hollande Clinical Pathology
Hickey Research Group Obstetrics and Gynaecology
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer Head of Laboratory Associate Professor Fred Hollande
Clinical Pathology
Honorary Appointments’ Research Projects Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance Professor Christopher Christophi Surgery
Identification of biomarkers to novel therapies in Myelodysplasia Professor David S Ritchie Medicine and Radiology
Identification of novel therapeutic targets in mucinous ovarian cancer Dr Jessica Holien Medicine and Radiology
Identifying and characterising Lynch syndrome within the population Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying biomarkers of risk and poor prognosis in CRC Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Improving Cancer Outcomes for Culturally and Linguistically Diverse (CaLD) Communities Project Leader, Prof Jon Emery General Practice
Informal Communities in Cancer Treatment Project Lead Dr Matt Grant Medicine and Radiology
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer Group Leader, acting Head of Department Associate Professor Fred Hollande Clinical Pathology
Investigating the link between phenotype change and treatment resistance in prostate cancer Associate Professor Niall Corcoran Surgery
Liver Group Professor Christopher Christophi
Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Manometric studies on oesophageal atresia and colorectal disorders Project Leader Dr Sebastian King Paediatrics
Metastasis Research Group Professor Albert G Frauman
Medicine and Radiology
microRNAs in Endometrial Cancer Dr Ellen Menkhorst Obstetrics and Gynaecology
Molecular Mechanisms of Tumour Resistance Laboratory Dr Rodney Luwor Surgery
Molecular Microbiology and Reproductive Health Research Group Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland
Obstetrics and Gynaecology
New reagent for detection of program cell death Dr Peter J Wookey Medicine and Radiology
NHMRC Centre for Research Excellence for Reducing the Burden of Colorectal Cancer by Optimising Screening Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research
General Practice
Novel investigations and treatments for intractable, chronic constipation Project Leader Dr Bridget Southwell Paediatrics
Novel treatments for colorectal disorders Project Leader Dr Sebastian King Paediatrics
Optimising the management of patients awaiting liver transplantation Professor Christopher Christophi
Senior Lecturer Michael Fink
Surgery
Paediatric and Adolescent Fertility Preservation Taskforce Senior Lecturer Yasmin Jayasinghe
Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Palliative Medicine Research Group Group Leader Professor Jennifer Philip
Medicine and Radiology
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility Project Leader Dr Ruili Li Paediatrics
Predicting tumour evolution, immune surveillance and editing using integromic classification of the tumour microenvironment Associate Professor Daniel Buchanan Clinical Pathology
Prediction of ovarian malignancy in children with ovarian cysts Dr Yasmin Jayasinghe Obstetrics and Gynaecology
Preparing for clincial trials of synchrotron microbeam radiation therapy for cancer treatment Professor of Women's Health Research Professsor Peter Rogers Obstetrics and Gynaecology
Prevalence of Risk Factors for Melanoma in Primary Care Patients using the MelaTools Risk Calculator Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research,
General Practice
Priorities and Needs of Women Living with Advanced Cancer Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Priorities and Needs of Women Living with Advanced Cancer Dr Michelle Peate Obstetrics and Gynaecology
Prostate cancer progression inhibition Group Leader Professor Albert G Frauman Medicine and Radiology
Prostate Cancer Research Group Professor Christopher Hovens
Surgery
Rare Disease Oncogenomics Head of Laboratory Dr Richard Tothill
Clinical Pathology
Reducing disparities in mortality and survival for rural Victorians with colorectal cancer Rebecca Bergin General Practice
Regulation of cancer stem cell self-renewal in colorectal cancer Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion Dr Stanley Stylli Surgery
Regulation of invadopodium function and involvement in cancer cell invasion Dr Stanley Stylli Surgery
Regulators of allogeneic stem cell engraftment, graft versus host disease and graft-versus leukaemia Group Leader Professor David Ritchie Medicine and Radiology
Reproductive Steroids Research Group Professor Mathis Grossmann, MD, PhD, FRACP
Medicine and Radiology
The role of the essential biometal zinc in pathological and physiological processes Professor Graham Baldwin
Dr Oneel Patel
Dr Joseph Ischia
Surgery
Role of p-21-activated kinases in pancreactic cancer Professor Graham Baldwin
Dr Mehrdad Nikfarjam
Surgery
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection Professor Christopher Christophi Surgery
Roles of macrophages subpopulations in tumour microenvironment in gastric cancer Dr Adrian Achuthan Medicine and Radiology
Sepsis pathway compliance and outcomes for haematology patients Prof Monica Slavin Medicine and Radiology
Serum biomarkers of brain cancer Dr Andrew Morokoff Surgery
Spinal Biology Laboratory Doctor Gerald Quan
Surgery
STEP Care Trial Project Lead Anna Collins Medicine and Radiology
Structural biology of proteins involved in cancer Dr Craig Morton Medicine and Radiology
Structure-based drug design of selective Drp1 inhibitors Dr Jessica Holien Medicine and Radiology
Studying the Continuum of Cancer Care through Linking Primary Data Research Project Leader Professor Jon Emery General Practice
Supporting earlier cancer diagnosis and efficient referral pathways in general practice General Practice
Surgical Research Group Chair of Paediatric Surgery Professor John M Hutson AO
Paediatrics
Targeting the angiogenic and osteoclastic pathways in spinal cancer Doctor Gerald Quan
Doctor Gerald Quan
Surgery
Targeting the Lymphatics in colorectal Liver metastasis Professor Christopher Christophi Surgery
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production Professor Michael McCullough Surgery
The CGA-Oncology Study: Comprehensive geriatric assessment and intervention in older lung cancer patients Project Lead Professor Andrea B Maier Medicine and Radiology
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer Dr Peter J Wookley Medicine and Radiology
The Genomic Drivers of High Risk Prostate cancer Professor Christopher Hovens Surgery
The Impact of Inflammation-Driven Cancers on Immune Ageing Prof David Ritchie Medicine and Radiology
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit Research Group Leader Dr Michelle Peate
Obstetrics and Gynaecology
The role of EGFR Signaling in Glioblastoma Progression and Resistance to Current Therapies Dr Rodney Luwor Surgery
The role of FANCM gene in inherited breast cancer A/Prof Andrew Deans Medicine and Radiology
The role of invadopodia in glioma invasion and response to therapeutics Dr Stanley Stylli Surgery
The role of invadopodia in glioma invasion and response to therapeutics Dr Stanley Stylli Surgery
The role of miRNA in oral mucosal disorders Professor Michael McCullough Surgery
The role of RECQL4 gene in cancer predispositon Dr Andrew Deans Medicine and Radiology
The role of STAT3-mediated Cancer Progression and Resistance to Current Therapies Dr Rodney Luwor Surgery
The treatment of the brain tumour glioblastoma (GBM) Dr Peter J Wookey Medicine and Radiology
Treatment outcome in older lung cancer patients: does the biological age predict it? Prof. Andrea Maier Medicine and Radiology
Ultrasound Group Leader Professor Robert N Gibson
Medicine and Radiology
Understanding how A-to-I RNA editing modifies the immunogenicity of endogenous RNA A/Prof Carl Walkley Medicine and Radiology
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies Prof David Ritchie Medicine and Radiology
Understanding the aetiology of Serrated Polyposis Syndrome Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma Surgeon, Project Leader Dr David Gyorki Surgery
Understanding the microenvironment of lymphodema Dr Ramin Shayan Surgery
Understanding the role of CXCR7 in lymphodema following radiation injury Dr Ramin Shayan Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism Project Leader Professor John M Hutson AO Paediatrics
Use of Connexin43 peptides as a treatment for glioma Dr Stanley Stylli Surgery
Western Health Cancer Research Group Leader Professor Michael Green
Medicine and Radiology
WomenCAN: Promoting and advancing women’s health and wellbeing after cancer Dr Michelle Peate Obstetrics and Gynaecology
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study. Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey Obstetrics and Gynaecology
WORKPLAN#3: NON-SURGICAL ALTERNATIVES

118