Cancer in Medicine

Groups / Projects	Research Lead	Dept / Centre
A monoclonal antibody (mAb1F5) has been developed that identifies the expression of a putative growth factor	Dr Peter Wookey	Medicine and Radiology
A mouse model of duodenal atresia	Project Leader Associate Professor Warrick Teague	Paediatrics
A phase I/II double-blind, randomised controlled trial assessing effect of medicinal cannabis on overall quality of life for people with cancer		Medicine and Radiology
A randomised controlled trial of short-course antibiotics in children with cancer and febrile neutropenia	Dr Gabrielle Haeusler	Paediatrics
A systematic review of end of life quality of care indicators	Prof Jennifer Philip	Medicine and Radiology
A systematic review of the management of anxiety in palliative cancer patients	Prof Jennifer Philip	Medicine and Radiology
A systematic review of the management of nausea unrelated to cancer treatment	Prof Jennifer Philip	Medicine and Radiology
A systematic review of the management of sleep in palliative care cancer patients	Prof Jennifer Philip	Medicine and Radiology
A therapeutic strategy for killing cancer cells by DNA repair inhibition	A/Prof Andrew Deans	Medicine and Radiology
A5 SDHB Genomics Study	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Academic Department of Surgery, Western Health	Associate Professor Justin Yeung	Surgery
ACRF Translational Research Laboratory	Group Leader Professor David S Ritchie	Medicine and Radiology
Advanced Limb Reconstruction	Head of Department of Surgery, St. Vincent's Hospital, Professor Peter Choong	Surgery
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism	Dr Peter Wookey	Medicine and Radiology
Analysis of circulating microRNAs in patient serum as a non-invasive biomarker platform	Project Lead Dr Rachel Koldej	Medicine and Radiology
Boussioutas Laboratory: Gastrointestinal Cancer	Group Leader Professor Alex Boussioutas	Medicine and Radiology
Brain Cancer Microenvironment and Biology Laboratory	Dr Theo Mantamadiotis	Surgery
Breast Cancer	Head of Group Professor Bruce Mann Lead Researcher Dr Anita Skandarajah	Surgery
Buchanan laboratory: Oncogenomics (colorectal cancer)	Head of Laboratory Associate Professor Daniel Buchanan	Clinical Pathology
Coin Laboratory: Cancer Bioinformatics	Head of Laboratory Professor Lachlan Coin	Clinical Pathology
Cancer Biology Research Group	Professor Graham Baldwin	Surgery
Cancer drug discovery by inhibition of a DNA repair pathway with Crispr/Cas9 gene editing and biochemistry	Dr Wayne Crismani	Medicine and Radiology
Cancer Immunotherapy symptoms: the experience and expectations around management	Program Trial Coordinator Leeanne Pasanen	Medicine and Radiology
Cancer in Primary Care	Research Program Leader Professor Jon Emery	General Practice
Cancer Signaling Research Laboratory	Dr Hong-Jian Zhu	Surgery
Cardiovascular and Tumourivascular Laboratory	Dr Peter J Wookey Professor David Hare	Medicine and Radiology
Care Plus Study	Research Assistant Roslyn Le Gautier	Medicine and Radiology
Characterisation of complex structural variation in bacterial and human genomes	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Characterising Respiratory Infections in Immune-suppressed Haematology and Transplant Patients	Professor Monica Slavin	Medicine and Radiology
CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Circulating Biomarkers in Liver Malignancy	Professor Christopher Christophi	Surgery
CRISP-DNA: The feasibility of assessing bowel cancer risk using genomic testing to target screening in general practice	Herman Professor of Primary Care Cancer Research Professor Jon Emery	General Practice
Defining the Role of Transcriptional Stress Pathways in Cancer Cell Resistance Towards Anti-Cancer Therapeutics	A/prof John Price	Medicine and Radiology
Developing clinical genomic methods for cancer of unknown primary	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Development and validation of triage guidelines for colonoscopy and gastroscopy		General Practice
Endocrine Surgery	Associate Professor Julie Miller	Surgery
Enhance: A multi-centre, randomised phase IV study		Medicine and Radiology
Enteric Neuropathy as a Target to Alleviate Gastrointestinal Side-effects of Chemotherapy	A/prof Kulmira Nurgali	Medicine and Radiology
Establishing patterns of primary health care usage in cancer at the end of life	Matthew Grant	Medicine and Radiology
Fertility After Cancer Predictor (FoRECAsT) Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Fertility decision tools for young women with breast cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer	Senior Lecturer Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Fertility preservation in children with cancer	Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Finding a needle in the haystack: ctDNA detection for tracking cancer evolution and refining cancer risk	Associate Professor Daniel Buchanan	Clinical Pathology
Function and cryo-EM structure of the breast cancer predisposition gene BRCA1	A/Prof Andrew Deans	Medicine and Radiology
Genomic tools for diagnosis of the presence of a solid tumour and for prediction of tumour subtype and likely treatment response from circulating tumour DNA	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Genomic tools for rapid diagnosis of bacterial infection using host and bacterial biomarkers	Group Lead, Cancer Bioinformatics Professor Lachlan Coin	Clinical Pathology
Glioblastoma Survival Signaling Lab	Dr Rodney Luwor	Surgery
Gynaecology Research Centre	Professor Women's Health Research Professor Peter Rogers	Obstetrics and Gynaecology
Gynaecology Research Centre Hickey Research Group	Research Group Leader Professor Martha Hickey	Obstetrics and Gynaecology
Harnessing novel immunotherapies to restore immunity in chronic lymphocytic leukaemia	Group Leader Professor David Ritchie	Medicine and Radiology
Heterogeneity of treatment response in advanced cancer: role of intrinsic and microenvironmental factors	AProfessor Frederic Hollande	Clinical Pathology
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer	Head of Laboratory Professor Fred Hollande	Clinical Pathology
Honorary Appointments’ Research Projects		Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance	Professor Christopher Christophi	Surgery
Human Liver Organoids	Project Lead Professor Kumar Visvanathan	Medicine and Radiology
Identification and Characterisation of Molecular Mediators of Cancer Metastasis	A/prof John Price	Medicine and Radiology
Identification of biomarkers to novel therapies in Myelodysplasia	Professor David S Ritchie	Medicine and Radiology
Identifying and characterising Lynch syndrome within the population	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying better therapies for patients with myelodysplastic syndromes.	Professor Louise Purton	Medicine and Radiology
Identifying biomarkers of risk and poor prognosis in CRC	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Inflammation-induced Cancer: Mechanisms and Novel Treatments	A/prof Kulmira Nurgali	Medicine and Radiology
Informal Communities in Cancer Treatment	Project Lead Dr Matt Grant	Medicine and Radiology
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer	Group Leader, acting Head of Department Associate Professor Fred Hollande	Clinical Pathology
Investigating the link between phenotype change and treatment resistance in prostate cancer	Associate Professor Niall Corcoran	Surgery
Liver Group	Professor Christopher Christophi	Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Manipulating Recipient Immunological Microenvironment to Improve Outcomes in Allogeneic Transplantation	Prof David Ritchie	Medicine and Radiology
Manometric studies on oesophageal atresia and colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
Mesenchymal Stem Cell-based Therapies for Inflammatory Bowel Disease and Colorectal Cancer	A/prof Kulmira Nurgali	Medicine and Radiology
Metastasis Research Group	Professor Albert G Frauman	Medicine and Radiology
Molecular Mechanisms of Tumour Resistance Laboratory	Dr Rodney Luwor	Surgery
Molecular Microbiology and Reproductive Health Research Group	Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland	Obstetrics and Gynaecology
Neurosurgery	Professor Kate Drummond	Surgery
New reagent for detection of program cell death	Dr Peter J Wookey	Medicine and Radiology
NHMRC Centre for Research Excellence for Reducing the Burden of Colorectal Cancer by Optimising Screening	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research	General Practice
Novel Approaches in Therapeutic Endoscopy	A/prof Alan Moss	Medicine and Radiology
Novel genetic interactions with the double-stranded RNA-induced autoimmunity pathways	A/Prof Carl Walkley	Medicine and Radiology
Novel investigations and treatments for intractable, chronic constipation	Project Leader Dr Bridget Southwell	Paediatrics
Novel treatments for colorectal disorders	Project Leader Dr Sebastian King	Paediatrics
OPPtiC: A pilot feasibility study of establishing a clinical opioid pharmacogenomics database in palliative care	Program Trial Coordinator Leeanne Pasanen	Medicine and Radiology
Optimising the management of patients awaiting liver transplantation	Professor Christopher Christophi Senior Lecturer Michael Fink	Surgery
PaCCSC RAPID Series - Cancer-related Lymphoedema	Beth Russell	Medicine and Radiology
Paediatric and Adolescent Fertility Preservation Taskforce	Senior Lecturer Yasmin Jayasinghe	Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Palliative Nexus	Group Leader Professor Jennifer Philip	Medicine and Radiology
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility	Project Leader Dr Ruili Li	Paediatrics
Predicting tumour evolution, immune surveillance and editing using integromic classification of the tumour microenvironment	Associate Professor Daniel Buchanan	Clinical Pathology
Prediction of ovarian malignancy in children with ovarian cysts	Dr Yasmin Jayasinghe	Obstetrics and Gynaecology
Preparing for clincial trials of synchrotron microbeam radiation therapy for cancer treatment	Professor of Women's Health Research Professsor Peter Rogers	Obstetrics and Gynaecology
Prevalence of Risk Factors for Melanoma in Primary Care Patients using the MelaTools Risk Calculator	Project Leader Professor Jon Emery, Herman Professor of Primary Care Cancer Research,	General Practice
Priorities and Needs of Women Living with Advanced Cancer	Project Lead Dr Michelle Peate	Obstetrics and Gynaecology
Prostate Cancer	Head of Group Professor Christopher Hovens Deputy Laboratory Head Associate Professor Niall Corcoran	Surgery
Prostate cancer progression inhibition	Group Leader Professor Albert G Frauman	Medicine and Radiology
Prostate Cancer Research Group	Professor Christopher Hovens	Surgery
RAPID Postmarketing Study - Medicinal Cannabis		Medicine and Radiology
Rare Disease Oncogenomics	Head of Laboratory Dr Richard Tothill	Clinical Pathology
Reducing disparities in mortality and survival for rural Victorians with colorectal cancer	Rebecca Bergin	General Practice
Regulation of blood cell production by endothelial cell-derived retinoic acid receptor gamma	Professor Louise Purton	Medicine and Radiology
Regulation of cancer stem cell self-renewal in colorectal cancer	Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande	Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion	Dr Stanley Stylli	Surgery
Regulators of allogeneic stem cell engraftment, graft versus host disease and graft-versus leukaemia	Group Leader Professor David Ritchie	Medicine and Radiology
Renal supportive care of patients with advanced chronic kidney disease	Kathryn Ducharlet	Medicine and Radiology
Reproductive Steroids Research Group	Professor Mathis Grossmann, MD, PhD, FRACP	Medicine and Radiology
The role of the essential biometal zinc in pathological and physiological processes	Professor Graham Baldwin Dr Oneel Patel Dr Joseph Ischia	Surgery
Role of p-21-activated kinases in pancreactic cancer	Professor Graham Baldwin Dr Mehrdad Nikfarjam	Surgery
Role of the EHF transcription factor in breast cancer	Professor John Mariadason	Medicine and Radiology
Role of the Nervous System in Cancer Development and Progression	A/prof Kulmira Nurgali	Medicine and Radiology
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection	Professor Christopher Christophi	Surgery
Roles of macrophages subpopulations in tumour microenvironment in gastric cancer	Dr Adrian Achuthan	Medicine and Radiology
Sepsis pathway compliance and outcomes for haematology patients	Prof Monica Slavin	Medicine and Radiology
Serum biomarkers of brain cancer	Dr Andrew Morokoff	Surgery
Spinal Biology Laboratory	Doctor Gerald Quan	Surgery
STEP Care Clinical Trial	Project Lead Anna Collins	Medicine and Radiology
Structural biology of proteins involved in cancer	Dr Craig Morton	Medicine and Radiology
Studying the Continuum of Cancer Care through Linking Primary Data	Research Project Leader Professor Jon Emery	General Practice
Supporting earlier cancer diagnosis and efficient referral pathways in general practice		General Practice
Surgical Research Group	Chair of Paediatric Surgery Professor John M Hutson AO	Paediatrics
Targeting the angiogenic and osteoclastic pathways in spinal cancer	Doctor Gerald Quan Doctor Gerald Quan	Surgery
Targeting the Lymphatics in colorectal Liver metastasis	Professor Christopher Christophi	Surgery
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production	Professor Michael McCullough	Surgery
The CGA-Oncology Study: Comprehensive geriatric assessment and intervention in older lung cancer patients	Project Lead Professor Andrea B Maier	Medicine and Radiology
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer	Dr Peter J Wookey	Medicine and Radiology
The Genomic Drivers of High Risk Prostate cancer	Professor Christopher Hovens	Surgery
The impact of cancer therapies on the bone marrow microenvironment	Professor Louise Purton	Medicine and Radiology
The Impact of Inflammation-Driven Cancers on Immune Ageing	Prof David Ritchie	Medicine and Radiology
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit	Research Group Leader Dr Michelle Peate	Obstetrics and Gynaecology
The role of EGFR Signaling in Glioblastoma Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The role of FANCM gene in inherited breast cancer	A/Prof Andrew Deans	Medicine and Radiology
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of invadopodia in glioma invasion and response to therapeutics	Dr Stanley Stylli	Surgery
The role of miRNA in oral mucosal disorders	Professor Michael McCullough	Surgery
The role of RECQL4 gene in cancer predispositon	Dr Andrew Deans	Medicine and Radiology
The role of RNA editing enzyme ADAR1 in liver homeostasis and metabolism	A/Prof Carl Walkley	Medicine and Radiology
The role of STAT3-mediated Cancer Progression and Resistance to Current Therapies	Dr Rodney Luwor	Surgery
The treatment of the brain tumour glioblastoma (GBM)	Dr Peter J Wookey	Medicine and Radiology
Treatment outcome in older lung cancer patients: does the biological age predict it?	Prof. Andrea Maier	Medicine and Radiology
Ultrasound	Group Leader Professor Robert N Gibson	Medicine and Radiology
Understanding how immune cell function is impacted by novel therapies in patients with B cell malignancies	Prof David Ritchie	Medicine and Radiology
Understanding the aetiology of Serrated Polyposis Syndrome	Head of Laboratory Dr Daniel Buchanan	Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma	Surgeon, Project Leader Dr David Gyorki	Surgery
Understanding the microenvironment of lymphodema	Dr Ramin Shayan	Surgery
Understanding the role of CXCR7 in lymphodema following radiation injury	Dr Ramin Shayan	Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism	Project Leader Professor John M Hutson AO	Paediatrics
Use of Connexin43 peptides as a treatment for glioma	Dr Stanley Stylli	Surgery
Use of tools to detect medication related problems in emergency departments	Professor Elizabeth Manias	Psychiatry
VCCC Building Capability in Clinical Trials Program	Program Trial Coordinator Leeanne Pasanen	Medicine and Radiology
Western Health Cancer Research	Group Leader Professor Michael Green	Medicine and Radiology
WomenCAN: Promoting and advancing women’s health and wellbeing after cancer	Dr Michelle Peate	Obstetrics and Gynaecology
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study.	Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey	Obstetrics and Gynaecology
WORKPLAN#3: NON-SURGICAL ALTERNATIVES

152