Cancer in Medicine

Cancer in all its forms, encompasses research, prevention, detection, treatment, care and health system transformation to address this most significant burden of disease.

Groups / Projects Research Lead Dept / Centre
A mouse model of duodenal atresia Project Leader Associate Professor Warrick Teague Paediatrics
A study of the extracellular vesicles in glioblastoma tissue Dr Laura Vella Medicine and Radiology
A5 SDHB Genomics Study Head of Laboratory Dr Richard Tothill Clinical Pathology
Academic Department of Surgery, Western Health Associate Professor Justin Yeung
Surgery
ACRF Translational Research Laboratory Group Leader Professor David S Ritchie
Medicine and Radiology
ADAR1 and RNA editng Dr Alistair Chalk Medicine and Radiology
Advanced Limb Reconstruction Head of Department of Surgery,
St. Vincent's Hospital,
Professor Peter Choong

Surgery
An anti-calcitonin receptor (CTR) antibody for the detection of programmed cell death: the role of CTR in a novel adaptive response in a pre-apoptotic mechanism Dr Peter Wookey Medicine and Radiology
Analysing the mutations in calcitonin receptor (CTR) mRNA transcripts, and identifying the isoforms and polymorphisms of CTR expressed in high grade glioma cell lines from glioblastoma Dr Peter Wookey Medicine and Radiology
Analysis of circulating microRNAs in patient serum as a non-invasive biomarker platform Project Lead Dr Rachel Koldej Medicine and Radiology
Biomarkers of human papillomavirus-related cancers Dr Alyssa Cornall Obstetrics and Gynaecology
Boussioutas Laboratory: Gastrointestinal Cancer Group Leader Associate Professor Alex Boussioutas
Medicine and Radiology
Buchanan laboratory: Oncogenomics (colorectal cancer) Head of Laboratory Associate Professor Daniel Buchanan
Clinical Pathology
Building a Tumourigenesis Atlas for Lynch syndrome related-colorectal cancer A/Prof Daniel Buchanan Clinical Pathology
Cancer Biology Research Group Professor Graham Baldwin
Surgery
Cancer drug discovery by inhibition of a DNA repair pathway with Crispr/Cas9 gene editing and biochemistry Dr Wayne Crismani Medicine and Radiology
Cancer in Primary Care Research Group Leader Professor Jon Emery
General Practice
Cancer Signalling Research Laboratory Dr Hong-Jian Zhu
Surgery
Cardiovascular and Tumourivascular Laboratory Group Leader Dr Peter J Wookey
Medicine and Radiology
Cell death regulation in B cell immunity and B cell lymphona A/Prof Jorg Heierhorst Medicine and Radiology
Characterising the seeds of breast cancer metastasis Dr Delphine Merino Medicine and Radiology
Characterizing metastatic heterogeneity in colorectal cancer A/Prof Frederic Hollande Clinical Pathology
CHEST Australia Trial: An Intervention to Reduce Time-to-Consult with Symptoms of Lung Cancer Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research
General Practice
Circulating Biomarkers in Liver Malignancy Professor Christopher Christophi Surgery
Circulating nucleic acid biomarkers for tumour surveilance in Merkel cell carcinoma Dr Richard Tothill Clinical Pathology
CRISP-DNA: The feasibility of assessing bowel cancer risk using genomic testing to target screening in general practice Herman Professor of Primary Care Cancer Research Professor Jon Emery General Practice
Defining the role of p53 in cancer immunotherapy Prof Ygal Haupt Medicine and Radiology
Defining the Role of Transcriptional Stress Pathways in Cancer Cell Resistance Towards Anti-Cancer Therapeutics A/Prof John Price Medicine and Radiology
Determine the key signalling pathways/ genes that regulate phenotype changes in prostate cancer in response to androgen deprivation therapy. Dr Niall Corcoran Surgery
Developing a human pre-cancer atlas of colonic polyps for predicting future risk of colorectal cancer or polyps A/Prof Daniel Buchanan Clinical Pathology
Developing a multifactorial classification approach for germline variants in the colorectal cancer susceptibility genes POLE and POLD1 A/Prof Daniel Buchanan
Dr Khalid Mahmood
Clinical Pathology
Developing clinical genomic methods for cancer of unknown primary Head of Laboratory Dr Richard Tothill Clinical Pathology
Development and validation of triage guidelines for colonoscopy and gastroscopy General Practice
Dissecting the relevance of a novel molecular pathway in stem cells and immunodeficiencies Dr Mark Chong Medicine and Radiology
Epigenetic regulators of endometrial cancer as new treatment targets to halt metastatic spread. Professor Peter Rogers
Professor Eva Dimitriadis
Obstetrics and Gynaecology
Examining A New Drug Target For Preventing Stomach Cancer Professor Philip Sutton Paediatrics
Experiences and priorities of women living with ovarian cancer Dr Jennifer Marino
Dr Michelle Peate
Obstetrics and Gynaecology
Exploration of novel approaches to anti-cancer treatment: manipulation of mutant p53 Prof Ygal Haupt Medicine and Radiology
Fertility After Cancer Predictor (FoRECAsT) Study Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Fertility preservation in children and teenagers with cancer Senior Lecturer Dr Yasmin Jayasinghe Obstetrics and Gynaecology
Fertility preservation in children with cancer Dr Yasmin Jayasinghe
Obstetrics and Gynaecology
Genomic and Immune cell profiling of sebaceous skin lesions for optimising identification of patients with Lynch syndrome A/Prof Daniel Buchanan
Prof Ingrid Winship
Clinical Pathology
Gynaecology Research Centre Professor Women's Health Research Professor Peter Rogers
Obstetrics and Gynaecology
Harnessing novel immunotherapies to restore immunity in chronic lymphocytic leukaemia Group Leader Professor David Ritchie Medicine and Radiology
Hearing protection in surgery Dr Hayden Eastwood
Prof Stephen O’Leary
Surgery
Hickey Research Group Obstetrics and Gynaecology
Hollande laboratory: Tumour Heterogeneity in Metastatic Cancer Head of Laboratory Associate Professor Fred Hollande
Clinical Pathology
Honorary Appointments’ Research Projects Surgery
Host responses to therapy and the tumour microenvironment contribute to the development of tumour resistance Professor Christopher Christophi Surgery
Identification and Characterisation of Molecular Mediators of Cancer Metastasis A/ Professor John Price Medicine and Radiology
Identification of biomarkers to novel therapies in Myelodysplasia Professor David S Ritchie Medicine and Radiology
Identification of osteoblast lineage cells by fluorescence-activated cell sorting Dr Alistair Chalk Medicine and Radiology
Identifying and characterising Lynch syndrome within the population Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying better therapies for patients with myelodysplastic syndromes Meaghan Wall Medicine and Radiology
Identifying biomarkers of risk and poor prognosis in CRC Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Identifying novel genetic risk factors for colorectal cancer Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Improving Cancer Outcomes for Culturally and Linguistically Diverse (CaLD) Communities Project Leader, Prof Jon Emery General Practice
Improving therapy in breast cancer associated with an inherited risk Dr Andrew Deans Medicine and Radiology
Informal Communities in Cancer Treatment Project Lead Dr Matt Grant Medicine and Radiology
Inter and Intra-tumour heterogeneity in metastatic colorectal cancer Group Leader, acting Head of Department Associate Professor Fred Hollande Clinical Pathology
Investigating the effects of GM-CSF and M-CSF derived human macrophages on phagocytosing P. falciparum infected erythrocytes and cytokine production Dr Adrian Achuthan Medicine and Radiology
Investigating the link between histone modifications, gene expression and phenotype change in prostate cancer in response to androgen deprivation therapy. Doctor Niall Corcoran
Professor Christopher Hovens
Surgery
Investigating the role of signalling-specific mechanisms on tumour cell invasion Dr Theo Mantmadiotis
Dr Stanley Stylli
Surgery
Liver Group Professor Christopher Christophi
Surgery
Low Literacy Decision Aid about Reproductive Choices for Younger Women with Breast Cancer Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Manometric studies on oesophageal atresia and colorectal disorders Project Leader Dr Sebastian King Paediatrics
Metastasis Research Group Professor Albert G Frauman
Medicine and Radiology
Molecular Mechanisms of Tumour Resistance Laboratory Dr Rodney Luwor Surgery
Molecular Microbiology and Reproductive Health Research Group Honorary, Obstetrics and Gynaecology Royal Women's Hospital/Mercy Professor Suzanne M. Garland
Obstetrics and Gynaecology
New inhibitors for mitochondrial fission protein DRP1 Dr Jessica Holien
Dr Shiang (Max) Lim
Surgery
NHMRC Centre for Research Excellence for Reducing the Burden of Colorectal Cancer by Optimising Screening Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research
General Practice
Novel Approaches in Therapeutic Endoscopy Associate Professor Alan Moss Medicine and Radiology
Novel investigations and treatments for intractable, chronic constipation Project Leader Dr Bridget Southwell Paediatrics
Novel treatments for colorectal disorders Project Leader Dr Sebastian King Paediatrics
Optimising the management of patients awaiting liver transplantation Professor Christopher Christophi
Senior Lecturer Michael Fink
Surgery
Paediatric and Adolescent Fertility Preservation Taskforce Senior Lecturer Yasmin Jayasinghe
Obstetrics and Gynaecology
Paediatric Fertility Decision Aid Study Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Palliative Medicine Research Group Group Leader Professor Jennifer Philip
Medicine and Radiology
Postnatal germ cells are controlled by FSH during ‘minipuberty’ at 3-6 months of age, and deranged by cryptorchidism to cause seminoma and infertility Project Leader Dr Ruili Li Paediatrics
Preparing for clincial trials of synchrotron microbeam radiation therapy for cancer treatment Professor of Women's Health Research Professsor Peter Rogers Obstetrics and Gynaecology
Prevalence of Risk Factors for Melanoma in Primary Care Patients using the MelaTools Risk Calculator Project Leader Professor Jon Emery,
Herman Professor of Primary Care Cancer Research,
General Practice
Priorities and Needs of Women Living with Advanced Cancer Project Lead Dr Michelle Peate Obstetrics and Gynaecology
Prostate cancer progression inhibition Group Leader Professor Albert G Frauman Medicine and Radiology
Prostate Cancer Research Group Professor Christopher Hovens
Surgery
Rare Disease Oncogenomics Head of Laboratory Dr Richard Tothill
Clinical Pathology
Reducing disparities in mortality and survival for rural Victorians with colorectal cancer Rebecca Bergin General Practice
Regulation of Cancer Development by Transforming Growth Factor-beta Signalling Dr Hong-Jian Zhu
Surgery
Regulation of cancer stem cell self-renewal in colorectal cancer Group Leader, Acting deputy Head of Department Associate Professor Fred Hollande Clinical Pathology
Regulation of invadopodium function and involvement in cancer cell invasion Dr Stanley Stylli Surgery
Regulation of invadopodium function and involvement in cancer cell invasion Dr Stanley Styllianos Stylli
Surgery
Regulators of allogeneic stem cell engraftment, graft versus host disease and graft-versus leukaemia Group Leader Professor David Ritchie Medicine and Radiology
Reproductive Steroids Research Group Group Leader Professor Mathis Grossmann, MD, PhD, FRACP
Medicine and Radiology
Role of calcitonin receptor in stressed cells and diseased tissues: a new paradigm based on expression in the pre-apoptotic cell stress response Group Leader Dr Peter J Wookey Medicine and Radiology
The role of the essential biometal zinc in pathological and physiological processes Professor Graham Baldwin
Dr Oneel Patel
Dr Joseph Ischia
Surgery
Role of p-21-activated kinases in pancreactic cancer Professor Graham Baldwin
Dr Mehrdad Nikfarjam
Surgery
The role of the Renin Angiotensin System in tumour progression and recurrence following tumour resection Professor Christopher Christophi Surgery
Serum biomarkers of brain cancer Dr Andrew Morokoff Surgery
Sexual dysfunction in women who have experienced cancer Dr Jennifer Marino
Dr Michelle Peate
Obstetrics and Gynaecology
Spinal Biology Laboratory Doctor Gerald Quan
Surgery
STEP Care Trial Project Lead Anna Collins Medicine and Radiology
Structural biology of proteins involved in cancer Dr Craig Morton Medicine and Radiology
Studying the Continuum of Cancer Care through Linking Primary Data Research Project Leader Professor Jon Emery General Practice
Supporting earlier cancer diagnosis and efficient referral pathways in general practice General Practice
Supporting fertility presentation decisions in women with breast cancer Dr Michelle Peate
A/Prof Lesley Stafford
Obstetrics and Gynaecology
Surgical Research Group Chair of Paediatric Surgery Professor John M Hutson AO
Paediatrics
Targeting cell death pathways in biliary tract cancers Prof John Mariadason Medicine and Radiology
Targeting stem cells as a new treatment for stomach cancer Dr Trevelyan Menheniott
A/Professor Philip Sutton
Paediatrics
Targeting the angiogenic and osteoclastic pathways in spinal cancer Doctor Gerald Quan
Doctor Gerald Quan
Surgery
Targeting the Lymphatics in colorectal Liver metastasis Professor Christopher Christophi Surgery
Testing the effect of aspirin on colonic organoids from people with Lynch syndrome Dr Eric Jihoon Joo
A/Prof Fred Hollande
Clinical Pathology
The assessment of oral cancer risk using a chair-side tool for salivary aldehyde production Professor Michael McCullough Surgery
The CGA-Oncology Study: Comprehensive geriatric assessment and intervention in older lung cancer patients Project Lead Professor Andrea B Maier Medicine and Radiology
The experience of clinical trials for palliative care patients Prof Jennifer Philip Medicine and Radiology
The Genomic Drivers of High Risk Prostate cancer Professor Christopher Hovens
Doctor Niall Corcoran
Surgery
The health economics of caring for people with advanced cancer Prof Jennifer Philip Medicine and Radiology
The Medical Genome Reference Bank as a population control for germline variants in colorectal and prostate cancer Dr Bernard Pope
A/Prof Daniel Buchanan
Clinical Pathology
The Psychosocial Health and Wellbeing Research (emPoWeR) Unit Research Group Leader Dr Michelle Peate
Obstetrics and Gynaecology
The role of an isoform of calcitonin receptor in glioma stem cells Dr Peter Wookey Medicine and Radiology
The role of EGFR Signaling in Glioblastoma Progression and Resistance to Current Therapies Dr Rodney Luwor
Surgery
The role of FANCM gene in inherited breast cancer Dr Andrew Deans Medicine and Radiology
The role of invadopodia in glioma invasion and response to therapeutics Dr Stanley Stylli Surgery
The role of invadopodia in glioma invasion and response to therapeutics Dr Stanley Styllianos Stylli
Surgery
The role of miRNA in oral mucosal disorders Professor Michael McCullough Surgery
The role of RECQL4 gene in cancer predispositon Dr Andrew Deans Medicine and Radiology
The role of STAT3-mediated Cancer Progression and Resistance to Current Therapies Dr Rodney Luwor
Surgery
Ubiquitination and Fanconi Anemia Dr Andrew Deans Medicine and Radiology
Ultrasound Group Leader Professor Robert N Gibson
Medicine and Radiology
Understanding how A-to-I RNA editing modifies the immunogenicity of endogenous RNA Dr Alistair Chalk Medicine and Radiology
Understanding palliative care as an effective intervention Prof Jennifer Philip Medicine and Radiology
Understanding the aetiology of Serrated Polyposis Syndrome Head of Laboratory Dr Daniel Buchanan Clinical Pathology
Understanding The Immune Environment in Metastatic Melanoma Surgeon, Project Leader Dr David Gyorki Surgery
Understanding the microenvironment of lymphodema Dr Ramin Shayan
Dr Tara Karnezis
Surgery
Understanding the role of CXCR7 in lymphodema following radiation injury Dr Ramin Shayan
Dr Tara Karnezis
Surgery
Undescended testis and inguinal hernia result from defects in the same mechanism Project Leader Professor John M Hutson AO Paediatrics
Unravelling the aetiology of Colonic Polyposis through multi-omic profiling A/Prof Daniel Buchanan
Dr Mark Clendenning
Clinical Pathology
Use of Connexin43 peptides as a treatment for glioma Dr Stanley Stylli Surgery
Use of retinoic acid receptor ligands to increase the numbers of haematopoietic stem and progenitor cells for transplantation purposes Dr Alistair Chalk Medicine and Radiology
Western Health Cancer Research Group Leader Professor Michael Green
Medicine and Radiology
Impact of risk-reducing bilateral salpingo-oophorectomy on non-cancer outcomes in young high-risk women: a multicentre prospective study. Head, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital Professor Martha Hickey Obstetrics and Gynaecology
WORKPLAN#3: NON-SURGICAL ALTERNATIVES

140