The STRIDENT Study

  • Project Lead
    Professor Michael Kamm

Project Details

Stricture Definition and Treatment (the STRIDENT Study)

Most patients with Crohn’s disease at some stage develop complications of the disease and require an operation. The most common complication is bowel narrowing.

The STRIDENT studies aim to heal the bowel using intense treatment, or stretch narrowing more effectively, to prevent the need for an operation.

​The STRIDENT (Stricture Definition and Treatment) studies focus on treating Crohn’s disease complications more effectively. They examine how intense drug treatment can heal the bowel, preventing the need for surgery.  They also research more effective ways to safely stretch the bowel, relieving obstruction.​

​These are the first studies of this type in the world to address this particular Crohn’s disease complication.

Researchers

Professor Michael Kamm – Group Leader

Dr. Amy Hamilton – Clinical Scientist

Dr. Bronte Holt – Gastroenterologist

Ms. Alyson Ross – Research Nurse

Dr. Julien Schulberg – Gastroenterologist and PhD Fellow

Dr. Emily Wright – Gastroenterologist

Collaborators

AbbVie

Professor Mark Morrison – The University of Queensland Diamantina Institute

Dr Greg Moore – Monash University

Funding

NHMRC

AbbVie

The Spotlight Foundation

Research Publications

Schulberg, J.D., et al., Magnetic resonance enterography for predicting the clinical course of Crohn's disease strictures. J Gastroenterol Hepatol, 2019

Research Group

Kamm Gut Research Group


School Research Themes



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Medicine and Radiology

Node

St Vincent's Hospital

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