Characterising the functional role of VEZT in endometriosis
VEZT is the first protein coding gene that can be directly linked to increased susceptibility for endometriosis. At a population level, SNPs associated with an increased risk for endometriosis are also associated with increased VEZT expression in the endometrium.
The true significance of such inherited risk-associated variations in DNA can only be realized when they are linked to the altered regulation and function of specific genes and pathways modifying endometriosis risk. As such, we are now turning our attention to identifying the pathways regulated by VEZT and the functional role of VEZT in endometriosis.
Prof Peter Rogers –Research Director at the Women’s
Dr Sarah Holdsworth-Carson - Research Fellow
Dr Jacqueline Donoghue - Research Fellow
Dr Megan Cock – Project Officer
Leonie Cann – Research Assistant
Molly Churchill – Research Assistant
This research has been funded by the National Health and Medical Research Council (NHMRC)
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