Characterising the functional role of VEZT in endometriosis

Project Details

VEZT is the first protein coding gene that can be directly linked to increased susceptibility for endometriosis. At a population level, SNPs associated with an increased risk for endometriosis are also associated with increased VEZT expression in the endometrium.

The true significance of such inherited risk-associated variations in DNA can only be realized when they are linked to the altered regulation and function of specific genes and pathways modifying endometriosis risk. As such, we are now turning our attention to identifying the pathways regulated by VEZT and the functional role of VEZT in endometriosis.

Researchers

Prof Peter Rogers –Research Director at the Women’s

Dr Sarah Holdsworth-Carson - Research Fellow

Dr Jacqueline Donoghue - Research Fellow

Dr Megan Cock – Project Officer

Leonie Cann – Research Assistant

Molly Churchill – Research Assistant

Funding

This research has been funded by the National Health and Medical Research Council (NHMRC)

Research Opportunities

This research project is available to PhD students, Masters by Research, Honours students, Master of Biomedical Science to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Group

Gynaecology Research Centre - Rogers Group


School Research Themes

Women's Health



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Obstetrics and Gynaecology

Node

Royal Women’s Hospital

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