The Stand Up & Go Study: Physical activity and sitting time reduction program for older community members

Project Details

In Australia 1400 new cases of dementia are diagnosed each week with Alzheimer's Disease being the most common cause. Physical Activity (PA) appears to be one of the strongest factors to delay or prevent cognitive decline. Despite this, physical inactivity has been shown to increase with age. Prolonged sitting is now also acknowledged as a public health issue, with strong evidence that increased levels of sedentary behaviour are associated with cardiovascular disease, diabetes, and more recently, poor cognition.

The Stand Up & Go study is combining a PA program with a targeted program to reduce sitting time in vulnerable older adults who experience one or more major risk factors for cognitive decline (insufficiently active and T2DM). The aim of this pilot study is to investigate whether the participants can adhere successfully to such a combined intervention in comparison to a stand-alone PA program. If successful, the combined physical activity and sitting reduction intervention represents a safe, easily accessible, affordable and highly translatable program and the results of a future larger RCT could inform clinical practice guidelines.



  • Associate Prof Kay Cox, University of Western Australia;
  • Dr Elizabeth Cyarto, Jenny Southam, National Ageing Research Institute (NARI)
  • Professor Kaarin Anstey, Centre for Research on Ageing, Health and Wellbeing (CRAHW);
  • Dr Paul Gardiner, University of Queensland;
  • A/Prof Dina LoGuidice and Prof Patricia Desmond, Melbourne Health
  • A/Professor Neale Cohen, Baker IDI Heart and Diabetes Institute;
  • Professor David Dunstan
  • A/Professor Pramit Phal
  • Prof Danny Liew


  • Dementia Collaborative Research Centre (DCRC)

Research Group

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry, Ageing

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre


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