Cardiometabolic

The School has a varied and strong research history into cardiometabolic diseases, covering conditions including diabetes, obesity, heart disease and different cardiac pathologies.  We conduct cutting-edge research, translating into practical outcomes through our strong links and embedding within leading hospitals in Melbourne, with many of our leading researchers also being clinical practitioners allowing them to directly apply their research in their clinical practice.

Groups / Projects Research Lead Dept / Centre
Adipocyte Biology, Insulin Resistance and Cardiovascular Disease Group Leader Associate Professor Andrew Wilson Medicine and Radiology
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines Dr Peter Wookey Medicine and Radiology
An antibody that detects a high molecular weight surrogate ligand of calcitonin receptor is detected in malignant glioma cells and cell lines. Dr Peter J Wookley Medicine and Radiology
Arterial grafting for coronary artery revascularisation Co-director Colin Royse
Surgery
Assessment of mitochondrial function in a mouse model of obesity and type 2 diabetes A/Prof Sof Andrikopoulos Medicine and Radiology
Bio-engineering complex next generation human liver organoids Dr Geraldine Mitchell Surgery
Biomarkers of Atherosclerosis Group Leader Associate Professor Andrew Wilson Medicine and Radiology
Biomedical Translational Research Group: Developing Therapies for Cardiovascular Disease Group Leader Professor Darren Kelly
Medicine and Radiology
Cardiovascular and Tumourivascular Laboratory Dr Peter J Wookey
Professor David Hare
Medicine and Radiology
Characterization of GPR35 in models of cardiac and renal disease Dr Andrew Kompa Medicine and Radiology
Chronic Kidney Disease in the Management of people with Type 2 Diabetes in General Practice Project Leader Dr Jo-Anne Manski-Nankervis General Practice
Closed-loop bioelectrical neuromodulation control over bladder function Dr Sophie Payne Medical Bionics Department
Closing the Gap on Aboriginal Cardiovascular Health disparities- Using Big Data to understand the patient health journey Associate Professor Luke Burchill Medicine and Radiology
Cognitive Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Developing novel therapies for the treatment of retinal disease Professor Darren Kelly
Project Lead Dr Amanda Edgley
Medicine and Radiology
Diabetes and Cardio-Metabolic Conditions Research Program Leader Associate Professor John Furler
General Practice
Diabetes and Obesity Associate Professor Elif Ekinci
Professor Joe Proietto
Medicine and Radiology
Diabetes Discovery - prevalence and outcomes in inpatients with diabetes Project Leader Dr Elif Ekinci Medicine and Radiology
Diabetic Retinopathy and Health Informatics Collaboratory Group Leader Dr Laima Brazionis
Medicine and Radiology
Drug development for metabolic diseases A/Prof Jon Oakhill
Effect of uraemic toxins of vascular reactivity Dr Andrew Kompa Medicine and Radiology
Effects of gender-affirming hormone therapy Dr Ada Cheung Ada Cheung Medicine and Radiology
Engineering a tissue flap Dr Geraldine Mitchell Surgery
Evaluation of cardio-metabolic effects of Incretin-based therapies in type 2 diabetes Project Lead Professor Sanjoy Paul Medicine and Radiology
Evaluation of the obesity paradox in diabetes: A longitudinal case-control study of half a million patients Project Lead Professor Sanjoy Paul Medicine and Radiology
Exploring the acute effects of sleeve gastrectomy on mental health Dr Priya Sumithran Medicine and Radiology
Exploring the microbiome and epigenetic links in obesity development Dr Barbara Fam Medicine and Radiology
Factors that determine islet antigen-specific T cell expansion before the onset of Type 1 diabetes Prof Helen Thomas Medicine and Radiology
Gene signatures of the ‘lymphaticome’ Dr Ramin Shayan
Dr Tara Karnezis
Surgery
Genetic Analysis of Impaired beta Cell Function and Loss in Type 2 diabetes A/Prof Sof Andrikopoulos Medicine and Radiology
Hypoglycaemia and its consequences Project Lead Professor Sanjoy Paul Medicine and Radiology
Imaging Group Leader Professor Cassandra Szoeke Medicine and Radiology
Improving the health and well-being of the trans and gender diverse community Dr Ada Cheung Ada Cheung Medicine and Radiology
Inhibiting hypoxia and inflammation-induced damage to improve the outcomes of islet transplantation Dr Michaela Waibel Medicine and Radiology
Inhibition of microglia inflammation by AMPK for obesity treatment Dr Sandra Galic Medicine and Radiology
Investigating a novel mechanism for improving beta-cell function in type 2 diabetes Dr Kim Loh Medicine and Radiology
Investigating cardiovascular disease in Friedreich's ataxia using human induced pluripotent stem cells Dr Shiang (Max) Lim Surgery
Lifestyle and Prevention Group Leader Professor Cassandra Szoeke Medicine and Radiology
Lifestyle Factors and Cognitive Health Professor Cassandra Szoeke Medicine and Radiology
Lipoproteins and Cardiovascular Risk from Mid- to Late-life in Women Senior Research Fellow Alexandra Gorelik Medicine and Radiology
Management of acute decompensated heart failure in inpatients with diabetes Project Leader Dr Elif Ekinci Medicine and Radiology
Mental Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Modelling diabetic-induced cardiomyopathy using human cardiac organoids Dr Shiang (Max) Lim Surgery
Multimorbidity in Ageing Group Leader Professor Cassandra Szoeke Medicine and Radiology
Multimorbidity and glycaemia in people with type 2 diabetes attending Australian general practice: a cross-sectional study utilising data from NPS MedicineInsight Principal Investigator Dr Jo-Anne Manski-Nankervis General Practice
Musculoskeletal and Bone Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
New reagent for detection of program cell death Dr Peter J Wookey Medicine and Radiology
Non-alcoholic fatty liver disease – characterising disease features in order to develop new therapies Dr Amanda Edgley Medicine and Radiology
Novel therapies for the treatment of cardiorenal disease Project Lead Dr Andrew Kompa Medicine and Radiology
Novel therapies for the treatment of cardiorenal syndrome Dr Andrew Kompa Medicine and Radiology
Novel therapies for the treatment of cardiovascular disease Professor Darren Kelly
Project Lead Dr Amanda Edgley
Medicine and Radiology
Pathophysiology of glycaemic and cardiovascular risk factors in diabetes Project Lead Professor Sanjoy Paul Medicine and Radiology
Pharmacological approaches to food craving Dr Priya Sumithran Medicine and Radiology
Point of Care Ultrasound Simulation Education Dr David Canty Surgery
Quality of Life Group Leader Professor Cassandra Szoeke Medicine and Radiology
Refining the comprehensive geriatric assessment Prof. Andrea Maier Medicine and Radiology
Regulation of ghrelin signalling by AMPK Dr Sandra Galic Medicine and Radiology
Simplifying clinical acid-base diagnosis in critical care Professor David Story Medicine and Radiology
Sternal ultrasound assessment of plate vs. wire fixation Prof Alistair Royse Surgery
Structure-based drug design of selective Drp1 inhibitors Dr Jessica Holien Medicine and Radiology
Targeting inflammation and fibrosis for the treatment of retinal disease Dr Roy Kong Medicine and Radiology
The blood pressure drop makes you fall Prof. Andrea Maier Medicine and Radiology
The cellular fuel gauge: Novel mechanisms of metabolic control A/Prof Jon Oakhill Medicine and Radiology
The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer Dr Peter J Wookley Medicine and Radiology
The GP-OSMOTIC trial: Continuous Glucose Monitoring in Type 2 Diabetes Project Leader Associate Professor John Furler General Practice
The treatment of the brain tumour glioblastoma (GBM) Dr Peter J Wookey Medicine and Radiology
Tracking Physical Activity in Young Adults with Heart Disease Associate Professor Luke Burchill Medicine and Radiology
Trans Medical Research Dr Ada Cheung
Medicine and Radiology
Translational Cardiovascular Biology Group Leader Associate Professor Andrew Wilson
Medicine and Radiology
Transoesophageal echoardiography in cardiac surgery Co-director Colin Royse
Surgery
Treating fibrosis and inflammation to prevent end-organ damage in diabetes Dr Roy Kong Medicine and Radiology
Treatment outcome in older lung cancer patients: does the biological age predict it? Prof. Andrea Maier Medicine and Radiology
Type I interferon regulation of macrophage metabolism and activation Dr Andrew Fleetwood Medicine and Radiology
Ultrasound Education Group Co-director Professor Colin Royse
Professor Alistair Royse
Surgery
Understanding antibiotic prescribing and use of guidelines in general practice – the GP National Antimicrobial Prescribing Survey (GP NAPS) pilot study Principal Investigator Dr Jo-Anne Manski-Nankervis General Practice
Understanding how Type 17 immunity and IL-17 cytokines regulate Type 1 diabetes Dr Andrew Sutherland Medicine and Radiology
Understanding the role of Alzheimer’s tau protein in whole body glucose metabolism and type 2 diabetes Dr Evelyn Marin Medicine and Radiology
Using the JAK1/JAK2 Inhibitor Baricitinib to treat new-onset Type 1 diabetes Prof Helen Thomas Medicine and Radiology
Vascular Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
What are antigens/epitopes are recognized in by islet-infiltrating CD8+ T cells in people with type 1 diabetes? A/Prof Stuart Mannering Medicine and Radiology
Women's Healthy Ageing Project Group Leader Professor Cassandra Szoeke Medicine and Radiology

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