Musculoskeletal

Musculoskeletal diseases are identified as the second greatest cause of disability throughout the world and include conditions such as osteoporosis, sarcopenia and arthritis. Researchers are part of cross-functional and collaborative teams to study conditions related to disorders of the bone, muscle and joint for improvement in disease prevention and evidence-based care.

Groups / Projects Research Lead Dept / Centre
@AgeMelbourne Professor Andrea B Maier
Medicine and Radiology
A computer-aided decision system for gait analysis Project Leader Dr Morgan Sangeux Paediatrics
Advanced Limb Reconstruction Head of Department of Surgery,
St. Vincent's Hospital,
Professor Peter Choong

Surgery
An ultrasensitive assay to detect aggrecan degradation products in patient fluids Project Leader Professor Amanda Fosang Paediatrics
Arthritis Research Group Laboratory Head Professor Amanda Fosang
Paediatrics
BioFabrication of the osteo-chondral interface using multimodal 3D bioprinting Professor Peter Choong Surgery
Bioink development for cartilage tissue engineering Dr Cathal O'Connell Surgery
Biological mechanisms underpinning the social gradient of health Principal Fellow A/Prof Sharon Brennan-Olsen
Medicine and Radiology
Bone and Mineral Research Group Group Leader Professor John D Wark
Medicine and Radiology
Bone strength in young healthy females, older patients with low-trauma fracture and older healthy adults: peripheral quantitative computed tomography based finite element analysis Group Leader Prof. John D Wark Medicine and Radiology
Cognitive Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Community engagement and policy discourse: Musculoskeletal disease Principal Fellow A/Prof Sharon Brennan-Olsen
Medicine and Radiology
Controlled mechanical stimulation for cartilage regeneration modelling with 3D bioprinting techniques Dr Carmine Onofrillo Surgery
Dendritic cell cutaneous egression in Mycobacterium ulcerans infection Associate Professor John Hayman Clinical Pathology
Design of tensile strength tests for very soft materials Dr Cathal O'Connell Surgery
Determining the role of GM-CSF in osteoarthritis Associate Professor Andrew Cook Medicine and Radiology
Development of a Minimally Invasive Chronic Neural Interface Group Leaders Dr Nicholas Opie and Dr Thomas Oxley Medicine and Radiology
Development of Marrow Fat Quantification as a Predictor of Poor Outcomes in Osteosarcopenia Professor Gustavo Duque Medicine and Radiology
Development of mechanical testing protocols for very soft tissues Dr Cathal O'Connell Surgery
Diagnostic accuracy of a screening tool to identify patients at risk of sarcopenia Dr Esmee Reijnierse Medicine and Radiology
Diffusion properties in hydrogel materials Dr Cathal O'Connell Surgery
Dynamic microfluidic in vitro differentiation of stem cells for cartilage regeneration in surgical 3D bioprinting Dr Carmine Onofrillo Surgery
Elucidating molecular signalling pathways controlled by anti-inflammatory steroids Dr Adrian Achuthan Medicine and Radiology
Evaluating the impact of obesity on knee load over time in those who have undergone optimal surgical re-alignment after total knee replacement Professor Peter Choong Surgery
Generation of an ex vivo regeneration model for 3D bioprinting applications Dr Carmine Onofrillo Surgery
Healthy Ageing Program Group Leader Professor Cassandra Szoeke
Medicine and Radiology
How are autophagic processes involved in bone mineralisation? Prof Natalie Sims Medicine and Radiology
Hugh Williamson Gait Laboratory/Orthopaedic Department Research Group Leader Professor Kerr Graham
Paediatrics
Identifying novel cartilage proteins with new functions Project Leader Professor Amanda Fosang Paediatrics
Imaging Group Leader Professor Cassandra Szoeke Medicine and Radiology
In Vivo Tibiofemoral Biomechanics in Healthy Adults During Functional Activity Dr Hans Gray Surgery
Investigating the neural mechanisms of androgen action in the regulation of the musculoskeletal system. Project Lead Associate Professor Rachel Davey Medicine and Radiology
Is muscle surgery or bone surgery better for young children with cerebral palsy who have hip displacement? The Cerebral Palsy Hip Interventions Project (CP-HIP) Project Leader Dr Kate Willoughby Paediatrics
Lifestyle and Prevention Group Leader Professor Cassandra Szoeke Medicine and Radiology
Mental Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Mice resistant to collagen degradation teach us about skeletal development and arthritis Project Leader Professor Amanda Fosang Paediatrics
Mindfulness, cognitive processes and coping in chronic illness: insights from a study of joint replacement surgery Professor Peter Choong Surgery
Molecular signalling pathways controlling gene expression during chronic disease progression Dr Adrian Achuthan Medicine and Radiology
Multimedia (MyStay) Intervention for managing patient experience (MIME) following total hip replacement surgery: a cluster randomised trial. Ms Jo McDonall Surgery
Multimorbidity in Ageing Group Leader Professor Cassandra Szoeke Medicine and Radiology
Musculoskeletal and Bone Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Neural modelling of epileptic dynamics Dr Andre Peterson Medicine and Radiology
Nutritional needs of hospitalized older patients admitted to geriatric rehabilitation wards Dr Esmee Reijnierse Medicine and Radiology
Outcomes of Hip Interventions for Children with Cerebral Palsy – An International, Multi-Centre Prospective, Comparative Cohort Study Project Leader Dr Kate Willoughby Paediatrics
Postoperative Quality of Recovery Co-director Colin Royse
Surgery
Pre-Clinical Studies Identifying Novel Molecular Regulators of Skeletal Muscle Growth and Atrophy Associate Professor Alan Hayes Medicine and Radiology
Probing the complexity of cartilage using the Atomic Force Microscope Dr Cathal O'Connell Surgery
Quality of Life Group Leader Professor Cassandra Szoeke Medicine and Radiology
Refining the comprehensive geriatric assessment Prof. Andrea Maier Medicine and Radiology
Reproductive Steroids Research Group Professor Mathis Grossmann, MD, PhD, FRACP
Medicine and Radiology
Research at Epworth Professor Richard de Steiger
Rheumatology Group Leader Associate Professor Keith Lim
Medicine and Radiology
Sex based differences in response to total joint replacement for osteoarthritis of the lower limb A/Prof Michelle Dowsey Surgery
Single Event Multilevel Surgery in Bilateral Spastic Cerebral Palsy: A Multi-centre, Long-term, Follow-up Study Project Leader Dr Pam Thomason Paediatrics
Social determinants of musculoskeletal disease across the lifecourse Principal Fellow A/Prof Sharon Brennan-Olsen
Medicine and Radiology
Sternal ultrasound assessment of plate vs. wire fixation Prof Alistair Royse Surgery
Structural biology of proteins involved in bone diseases Dr Brett Bennetts Medicine and Radiology
Surgery Research Surgery
Synovial Knee Arthritis Research (SKAR) Professor John Hamilton Surgery
The actions of the male sex hormone, testosterone, to decrease fat mass. Project Lead Associate Professor Rachel Davey Medicine and Radiology
The Arthroplasty and Bariatric Surgery (ABS) Study: a randomised controlled trial of laparoscopic adjustable gastric banding prior to total knee arthroplasty Professor Peter Choong Surgery
The CGA Study: Development of an evidence based Comprehensive Geriatric Assessment Professor Andrea B Maier Medicine and Radiology
The Gait Outcomes Assessment List (GOAL): Validation of a new measure of gait function for children with cerebral palsy Project Leader Dr Pam Thomason Paediatrics
The MARKA Study: Maximum Acceptable Risk of complication in total Knee Arthroplasty Dr Michelle Dowsey Surgery
The power of human muscle Prof. Andrea Maier Medicine and Radiology
The role of an aggrecan 32mer fragment in developing osteoarthritis Project Leader Professor Amanda Fosang Paediatrics
The role of CCL17 in osteoarthritis Dr Kevin Lee Medicine and Radiology
The SHAPE Study: Nutritional Needs, Physical Function and Sarcopenia in Geriatric Outpatient Project Lead Professor Andrea B Maier Medicine and Radiology
Treatment outcome in older lung cancer patients: does the biological age predict it? Prof. Andrea Maier Medicine and Radiology
Type I interferon regulation of macrophage metabolism and activation Dr Andrew Fleetwood Medicine and Radiology
Understanding the effect of lower limb torsional deformities in typically developing children and adolescents Project Leader Dr Morgan Sangeux Paediatrics
Vascular Health Group Leader Professor Cassandra Szoeke Medicine and Radiology
Vascular remodeling in patients with Mycobacterium ulcerans infection and its effect on wound healing Associate Professor John Hayman Clinical Pathology
Vitamin D deficiency and balance Dr Marjan Tabesh Medicine and Radiology
What controls the development of strong cortical bone? Prof Natalie Sims Medicine and Radiology
Women's Healthy Ageing Project Group Leader Professor Cassandra Szoeke Medicine and Radiology

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